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Review article

First published 2024-10-18

BACE Inhibitor Clinical Trials for Alzheimer’s Disease

Elyse A. Watkins, Robert Vassar

Journal of Alzheimer’s Disease

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Research article

First published 2013-9-9

AβPP-Selective BACE Inhibitors (ASBI): Novel Class of Therapeutic Agents for Alzheimer's Disease

Olivier Descamps, Patricia Spilman, Qiang Zhang [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2017-2-20

BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer’s Disease Markers in Elderly Healthy Participants

Maarten Timmers, Soraia Barão, Bianca Van Broeck [...]

Journal of Alzheimer’s Disease

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Research article

First published

sAβPP α is a Potent Endogenous Inhibitor of BACE1

Clare Peters-Libeu, Jesus Campagna, Michael Mitsumori [...]

Journal of Alzheimer’s Disease

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Research article

First published 2017-12

BACE Inhibitors and Tau Protein Targeting Drugs in Prevention of Alzheimer’s Disease

Jonathan Orf, Scot Walker

Hospital Pharmacy

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Research article

First published 2014-7

A new insight into computational molecular design: A case study on BACE-1 inhibitors

Nima Razzaghi-Asl, Bahram Hemmateenejad, Ahmad Ebadi [...]

Journal of Computational Methods in Sciences and Engineering

Open access

Research article

First published 2024-02-29

What Threshold of Amyloid Reduction Is Necessary to Meaningfully Improve Cognitive Function in Transgenic Alzheimer’s Disease Mice?

Anita Singh, Matthew Maker, Jayant Prakash [...]

Journal of Alzheimer's Disease Reports

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Research article

First published 2021-01-05

Retinal Optical Coherence Tomography Metrics Are Unchanged in Verubecestat Alzheimer’s Disease Clinical Trial but Correlate with Baseline Regional Brain Atrophy

Robert C. Sergott, Annaswamy Raji, James Kost [...]

Journal of Alzheimer’s Disease

Free access

Research article

First published 2013-3

Development and Characterization of a Novel Membrane Assay for Full-Length BACE-1 at pH 6.0

Arman Saric, Lars zur Brügge, Dirk Müller-Pompalla [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2016-7

BACE-1 is expressed in the blood–brain barrier endothelium and is upregulated in a murine model of Alzheimer’s disease

Kavi Devraj, Slobodan Poznanovic, Christoph Spahn [...]

Journal of Cerebral Blood Flow & Metabolism

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