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Articles (57)

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1-10 of 57 results for Adaptive seamless design

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Select article: Adaptive Seamless Phase II/III Designs—Background,Operational Aspects,and Examples

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Other

First published 2006-12

Adaptive Seamless Phase II/III Designs—Background,Operational Aspects,and Examples

Jeff Maca, Suman Bhattacharya, Vladimir Dragalin [...]

Therapeutic Innovation & Regulatory Science

Select article: An adaptive seamless Phase 2-3 design with multiple endpoints

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Research article

First published 2021-4

An adaptive seamless Phase 2-3 design with multiple endpoints

Man Jin, Pingye Zhang

Statistical Methods in Medical Research

Select article: Comparison of adaptive seamless Phase 2/3 designs for dose selection in clinical trials with multiple endpoints

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Research article

First published 2025-8

Comparison of adaptive seamless Phase 2/3 designs for dose selection in clinical trials with multiple endpoints

Man Jin

Clinical Trials

Select article: BARD: A seamless two-stage dose optimization design integrating backfill and adaptive randomization

Open access

Research article

First published 2025-8

BARD: A seamless two-stage dose optimization design integrating backfill and adaptive randomization

Yixuan Zhao, Rachael Liu, Jianchang Lin [...]

Clinical Trials

Select article: Adaptive Seamless Design for Establishing Pharmacokinetic and Efficacy Equivalence in Developing Biosimilars

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Research article

First published 2017-11

Adaptive Seamless Design for Establishing Pharmacokinetic and Efficacy Equivalence in Developing Biosimilars

Ryuji Uozumi, Chikuma Hamada

Therapeutic Innovation & Regulatory Science

Select article: A seamless Phase IIB/III adaptive outcome trial: Design rationale and implementation challenges

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Research article

First published 2015-2

A seamless Phase IIB/III adaptive outcome trial: Design rationale and implementation challenges

Y H Joshua Chen, Richard Gesser, Alain Luxembourg

Clinical Trials

Select article: An automation-based adaptive seamless design for dose selection and confirmation with improved power and efficiency

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Research article

First published 2021-4

An automation-based adaptive seamless design for dose selection and confirmation with improved power and efficiency

Lu Cui, Tianyu Zhan, Lanju Zhang [...]

Statistical Methods in Medical Research

Select article: Operational Challenges and Solutions with Implementation of an Adaptive Seamless Phase 2/3 Study

Free access

Meeting report

First published 2012-11

Operational Challenges and Solutions with Implementation of an Adaptive Seamless Phase 2/3 Study

Kimberly Spencer, Kelly Colvin, Brad Braunecker [...]

Journal of Diabetes Science and Technology

Select article: An Adaptive,Dose-Finding,Seamless Phase 2/3 Study of a Long-Acting Glucagon-like Peptide-1 Analog (Dulaglutide): Trial Design and Baseline Characteristics

Free access

Meeting report

First published 2012-11

An Adaptive,Dose-Finding,Seamless Phase 2/3 Study of a Long-Acting Glucagon-like Peptide-1 Analog (Dulaglutide): Trial Design and Baseline Characteristics

Mary Jane Geiger, Zachary Skrivanek, Brenda Gaydos [...]

Journal of Diabetes Science and Technology

Select article: Application of Adaptive Design Methodology in Development of a Long-Acting Glucagon-like Peptide-1 Analog (Dulaglutide): Statistical Design and Simulations

Free access

Meeting report

First published 2012-11

Application of Adaptive Design Methodology in Development of a Long-Acting Glucagon-like Peptide-1 Analog (Dulaglutide): Statistical Design and Simulations

Zachary Skrivanek, Scott Berry, Don Berry [...]

Journal of Diabetes Science and Technology

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