26:T4c5,

Elastography is an emerging imaging modality that allows noninvasive imaging of tissue stiffness changes and stiffness values associated with pathology or as a result of therapy. However, many currently-used systems for elastography rely on a fixed geometry transducer and compressor system for imaging. This configuration is disadvantageous for imaging difficult-to-reach regions that are currently accessible with conventional ultrasound. In this paper, we describe a handheld, portable stepper motor controlled system for elastography. This system may reduce motion and jitter errors that are prevalent in completely ‘freehand elastography’ that employs hand-induced compressions using the transducer. The latter also requires collection of large amounts of data and use of strain estimation algorithms that may not be sensitive to phase changes or use additional preprocessing to minimize decorrelation effects. The stepper motor controlled handheld system provides controlled compressions and synchronized data acquisition. Our technique yields elastograms of a low-contrast phantom that have contrast levels and contrast-to-noise ratios that are comparable to those obtained with a fixed geometry system.

27:T47c,

A computational model has been developed to observe the effects of several instrumental parameters and systematic error sources on ultrasonic volumetric flow measurements in vessels using an error compensation method proposed previously by the authors. The effects of two essential instrumental parameters, the gate length and pulse duration, on two intermediate flow results and an optimal correction factor as a function of the beam width-to-vessel diameter ratio (BWR) have been studied under steady flow conditions. The corrected flow results under typical combinations of those parameters show that by proper selection of a correction factor, the proposed method can compensate for those systematic errors. If the estimated BWR is within ±0.1 of the actual BWR value, the systematic error can be limited to within 6.5%. The study also shows that the compensation method can effectively reduce the errors caused by other systematic error sources such as the system sensitivity and high-pass filter function, as well as misalignment of the ultrasound beam from the center of the vessel.

28:T5b3,