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Anencephaly is a congenital defect in which the neural tube fails to fully close during the fourth week of embryonic development (Obeidi, Russell, Higgins, & O'Donoghue, 2010). The Medical Task Force on Anencephaly (1990) defined it as a condition with the following four characteristics: (a) A large portion of the skull is absent, (b) the scalp is absent over the skull defect, (c) the exposed tissue is hemorrhagic and fibrotic, and (d) the cerebral hemispheres are indistinguishable. Approximately one in every 4,647 births is affected by anencephaly, with an estimated 847 anencephalic infants born each year (Centers for Disease Control and Prevention, 2020). It is estimated that around 65% of anencephalic fetuses will die in utero, whereas those that survive to birth typically die within a few hours or days of life (Medical Task Force on Anencephaly, 1990). Anencephalic infants who do survive beyond birth often exhibit irregular breathing, requiring the use of mechanical ventilation to be kept alive. For decades, anencephalic infants have been the topic of a highly controversial and heated debate with regard to their status and potential as organ donors. Currently, anencephalic infants are not used as organ donors because they do not meet the criteria for brain death. To some, this seems like the elimination of a vital pool of organ donors, whereas others view this as preservation of the sanctity and dignity of human life. This highly disputed issue of anencephaly and how it relates to both brain death and organ donation is the topic of this discussion.

Historical and modern-day use of maggots for debridement is described. Included are benefits of maggot therapy based on the evidence. This article also includes method for procurement.

This study aimed to examine the studies on children with stoma/ostomy in the field of nursing in terms of nursing science.
This was a qualitative research based on a document analysis of the studies, and it was designed as a systematic review. It was carried out in accordance with the Centre for Reviews and Dissemination guide. The databases of EBSCOhost, PubMed, Science Direct, Google Scholar, and Web of Science were searched between January 2010 and October 2020, and the studies on ostomy in pediatric patients were examined. The search was conducted by using the English keywords including “ostomy/stoma, children, nursing care.” Inclusion and exclusion criteria to select studies were determined based on the PICOS method (P = populations, I = interventions, C = comparison, O = outcomes, and S = study type). Data were extracted by two researchers independently. All studies were examined in full text, and it was decided which studies to include in the systematic review.
In this study, 9,857 studies were found by entering the keywords in the first search. Among these, 87 studies were selected when their titles, abstracts, and keywords were examined. By the inclusion criteria, 20 studies from the EBSCOhost, PubMed, Scopus, Google Scholar, and Science Direct databases were included in the study.
It was observed that the most common studies were the ones that were investigating the problems experienced by the children with an ostomy and their parents and its effects on them. It has been suggested that this systematic review will form a base for the experimental or randomized controlled studies that are needed in the field of ostomy and make a contribution to the literature.


Needle procedures can be very painful for children and generate stress and anxiety. Virtual reality (VR) has been used to enhance a child's distraction for pain control during these procedures. This study aims to identify the advantages and limitations of VR used for pain control in procedures using needles in pediatrics.
Studies were limited to children aged 4–18 years undergoing a procedure involving needles and the use of VR with goggles, headset, or helmet. A comprehensive search strategy using CINAHL Complete, MedicLatina, Medline Complete, B-on, LILACS, and SciELO databases was undertaken to find relevant studies published from January 2015 to April 2020. The retained studies included experimental and quasi-experimental, randomized controlled trials and nonrandomized controlled trials as well as prospective and retrospective studies.
The search yielded 80 articles. Of these, six articles met the inclusion criteria. Advantages found with the use of VR were (a) decrease of pain; (b) improvement of communication; (c) increased probability of success in performing the procedures; (d) reduction of anxiety, stress, distress, and fear; (e) easier handling of equipment; (f) almost complete isolation of external noise; and (g) low cost, lightness, and ease of transportation. Disadvantages reported were goggles' size and annoyance from repeated play and the occasional side effect of nausea.
VR is considered an interactive digital therapeutic toy used with positive effects in clinical practice. As children become calmer, VR can also reduce nursing stress and improve communication between children and nurses.
The aim of this study was to test Katharine Kolcaba's theory of comfort by evaluating the effectiveness of integrative comfort care interventions on discomfort experienced by children (aged 5–10 years) during the postoperative period. An experimental approach, pretest-and-posttest control group design, was used for evaluating the effectiveness of integrative comfort care interventions on discomfort experienced by children. Sample was composed of 200 children, selected using purposive sampling technique with random assignment to experimental and control groups. Kolcaba's Comfort Theory was used to assess the child's condition and then plan and deliver integrative comfort care interventions. The steps that followed for data collection, planning, and implementing effective care were based on the presuppositions of the theory. The tools used for data collection were demographics, a Comfort Behaviors Checklist, and the Comfort Daisies tool. Comfort care interventions were delivered through nursing process approach. These interventions were addressed across physical, psychological, social, spiritual, and environmental aspects. After the application of theory, the analysis revealed improvement in the comfort level of the subjects. Mann–Whitney
