Please read the guidelines in full before submitting your manuscript.
Manuscripts not conforming to these guidelines may be returned.
This Journal is a member of the Committee on Publication Ethics.
The Journal recommends that authors follow the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals formulated by the International Committee of Medical Journal Editors (ICMJE).
Sage is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the author responsibilities section on the Sage Journal Author Gateway.
We also encourage you to familiarize yourself with our Editorial Policies and our Publication Ethics Policies.
Sage Publishing disseminates high-quality research and engaged scholarship globally, and we are committed to diversity and inclusion in publishing. We encourage submissions and peer review from a diverse range of authors and reviewers from across all countries and backgrounds. Read our diversity, equity, and inclusion pledge.
There are no fees payable to submit or publish in this journal. Open access options are available – see below.
Please read the guidelines below then submit your manuscript here.
Access: Subscription
Accepts preprints? Yes
Identity transparency: Single anonymized
Please note that this journal is online-only and does not offer print copies.
There are no fees payable to submit or publish in this journal.
Optional open access publishing is available for a fee via the Sage Choice program, and Open Access agreements, where authors can publish open access either discounted or free of charge depending on the agreement with Sage. Find out if your institution is participating by visiting Open Access Agreements at Sage. Open Access agreement eligibility is determined by the corresponding author’s affiliation matching an agreement at acceptance. For more information on Open Access publishing options at Sage please visit Sage Open Access.
For information on funding body compliance, and depositing your article in repositories, please visit Sage’s Author Archiving and Re-Use Guidelines and Publishing Policies.
Your article must be within the scope of the journal and be of sufficient quality. If not, it will not be reviewed. Please read the journal’s Aims and Scope to see if your article is appropriate.
The manuscript must be your original work, you must have the rights to the work, and you must have obtained and be able to supply all necessary permissions for the reproduction of any copyright works not owned by you, including figures, illustrations, tables, lengthy quotations, or other material previously published elsewhere.
Original Research
Original Research submissions should not exceed 5,000 words and six figures or tables (not including abstract, keywords, key messages summary, references, or supplemental material). Articles must be fully documented reports of original research, but should be as concise as possible without compromising the data. Articles should be organized as follows: Title Page (including title, author names and affiliations, corresponding author, acknowledgements, running head and abbreviations), Structured Abstract (350 words max), Key Messages, Introduction, Methods, Materials & Methods, Results, Discussion, Conflict of Interest, Acknowledgments, References, Tables, Figure Legends, and Supplemental Material.
Please include the key messages of your article after your abstract using the following headings. This section should be no more than 3-5 sentences and should be distinct from the abstract; be succinct, specific, and accurate.
This will be published as a summary box after the abstract in the final published article.
Brief Report
These reports should be of scientific excellence in clinical or translational research, but not sufficient to warrant publication as Original Research. Examples of appropriate Brief Reports may include: (1) studies that report limited but provocative observations OR (2) relevant negative studies that can provide new information on important topics.
The text of a Brief Report is limited to 2,000 words. Brief Reports should include an unstructured abstract of no more than 350 words and no more than two display items.
Systematic Review
This article type includes all research reviews that systematically synthesize evidence (e.g., systematic reviews, meta-analysis, scoping reviews, mixed methods reviews, etc). Please include the research type in your title to make the nature of your study clear.
Follow Original Research article requirements.
Review
Narrative review articles are expected to be comprehensive, scholarly, and balanced, presenting an expert curation of the medical literature on the topic of interest. Originality is critical in order to contribute to the medical literature, and the perspective should be fresh and the synthesis unique. Authors of reviews should realize that the Journal is multidisciplinary and that reviews for such a journal require appropriate interpretive material. Clarity of presentation is a major criterion for acceptance.
Generally, reviews are limited to an unstructured 350-word abstract, 4,000-word text, excluding references, and five figures. Authors are encouraged to consult the Editor before submitting a review for consideration.
Research Tools and Issues
Research Tools and Issues are scholarly works and educational reviews focusing on areas of broad interest to the research community, including topics relevant to the conduct of clinical research, mentoring, and career development.
Manuscripts should not exceed 4,000 words, excluding title page, abstract, references, and supplemental material
Experimental Biology Symposia
The AFMR sponsors one or more symposia each year within the context of the Experimental Biology meeting. These symposia are translational in focus and are designed to highlight important recent basic science developments that are being brought to the bedside. It is anticipated that each presenter within each symposium will submit a manuscript to Journal of Investigative Medicine that summarizes the work described in their symposium talk.
Each manuscript should be self-contained, as the publication may not be coordinated with the publication of other manuscripts from the same symposium. The presenters are encouraged to present sufficient background and detail to permit a full appreciation of the importance and implications of their work. It is anticipated that most Experimental Biology Symposium manuscripts will be 2,000-6,000 words in length. The liberal use of figures and diagrams is encouraged.
Please include the key messages of your article after your abstract using the following headings. This section should be no more than 3-5 sentences and should be distinct from the abstract; be succinct, specific and accurate.
This will be published as a summary box after the abstract in the final published article.
Letters to the Editor
Letters to the Editor commenting on published articles may be submitted. These comments should be directed at confirming the results (from a different approach), extending the original report, or refuting results or the authors' interpretation. Maximum length is 1000 words; maximum number of references is 15. The Editor reserves the right to decide on publication of letters, shorten them, remove objectionable comments, and make other changes in accord with the style of the journal.
The Sage Author Gateway has some general advice on how to get published, plus links to further resources
The journal conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first participant enrollment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.
Your manuscript must follow the relevant EQUATOR Network reporting guidelines, depending on the type of study. The EQUATOR wizard can help identify the appropriate guideline. You will need to upload the appropriate checklist with your submission.
Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives.
If your research involves animals, you will be asked to confirm that you have carefully read and adhered to the ARRIVE guidelines.
The preferred format for your manuscript is Word. You do not need to follow a template, but please ensure your heading levels are clear, and the sections clearly defined.
Your article title, keywords, and abstract all contribute to its position in search engine results, directly affecting the number of people who see your work. For details of what you can do to influence this, visit How to help readers find your article online.
Your manuscript’s title should be concise, descriptive, unambiguous, accurate, and reflect the precise contents of the manuscript. A descriptive title that includes the topic of the manuscript makes an article more findable in the major indexing services.
Please include an abstract of to 350 words between the title and main body of your manuscript that concisely states the purpose of the research, major findings, and conclusions. For Original Research submissions, a structured abstract is required using the following headings: Background, Purpose, Study Type, Population, Assessment Technique(s) or Outcome(s), Statistical Tests, Results, and Data Conclusion. If your research includes clinical trials, the trial registry name and URL, and registration number must be included at the end of the abstract. Submissions that do not meet this requirement will not be considered.
Please include a minimum of 4-5 keywords, listed after the abstract. Keywords should be as specific as possible to the research topic.
For guidance on the preparation of illustrations, pictures, and graphs in electronic format, please read Sage’s artwork guidelines.
Figures supplied in color will appear in color online.
Please ensure that you have obtained any necessary permission from copyright holders for reproducing any illustrations, tables, figures, or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please see the Frequently Asked Questions page on the Sage Journal Author Gateway.
Please include a section with the heading ‘Statements and Declarations’ at the end of your submitted article, after the Acknowledgements section [and Author Contributions section if applicable] including each of the sub-headings listed below. If a declaration is not applicable to your submission, you must still include the heading and state ‘Not applicable’ underneath. Please note that you may be asked to justify why a declaration was not applicable to your submission by the Editorial Office.
Please include your ethics approval statements under this heading, even if you have already included ethics approval information in your methods section. If ethical approval was not required, you need to explicitly state this. You can find information on what to say in your ethical statements as well as example statements on our Publication ethics and research integrity policies page.
All papers reporting studies involving human participants, human data or human tissue must state that the relevant Ethics Committee or Institutional Review Board approved the study, or waived the requirement for approval, providing the full name and institution of the review committee in addition to the approval number. If applicable, please also include this information in the Methods section of your manuscript.
Please include any participant consent information under this heading and state whether informed consent to participate was written or verbal. If the requirement for informed consent to participate has been waived by the relevant Ethics Committee or Institutional Review Board (i.e. where it has been deemed that consent would be impossible or impracticable to obtain), please state this. If this is not applicable to your manuscript, please state ‘Not applicable’ in this section. More information and example statements can be found on our Publication ethics and research integrity policies page.
Submissions containing any data from an individual person (including individual details, images or videos) must include a statement confirming that informed consent for publication was provided by the participant(s) or a legally authorized representative. Non-essential identifying details should be omitted. Please do not submit the participant’s actual written informed consent with your article, as this in itself breaches the patient’s confidentiality. The Journal requests that you confirm to us, in writing, that you have obtained written informed consent to publish but the written consent itself should be held by the authors/investigators themselves, for example in a patient’s hospital record. The confirmatory letter may be uploaded with your submission as a separate file in addition to the statement confirming that consent to publish was obtained within the manuscript text. If this is not applicable to your manuscript, please state ‘Not applicable’ in this section.
The journal requires a declaration of conflicting interests from all authors so that a statement can be included in your article. For guidance on conflict of interest statements, see our policy on conflicting interest declarations and the ICMJE recommendations.
If no conflict exists, your statement should read: ‘The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article’.
All articles need to include a funding statement, under a separate heading, even if you did not receive funding. You’ll find guidance and examples on our Funding page.
The Journal is committed to facilitating openness, transparency and reproducibility of research, and has the following research data sharing policy. For more information, including FAQs please visit the Sage Research Data policy pages.
Subject to appropriate ethical and legal considerations, authors are encouraged to:
Number references consecutively in the order they appear in the manuscript. Use superscript numerals to identify references in text, tables, and figure legends. References cited only in tables or figure legends should be numbered last. Use the style set forth in 'Uniform Requirements for Manuscripts Submitted to Biomedical Journals,' (http://www.nlm.nih.gov/bsd/uniform_requirements.html). The titles of journals should be abbreviated according to the style used in the list of Journals Indexed for MEDLINE, as found in PubMed, posted by the US National Library of Medicine.
Every in-text citation must have a corresponding citation in the reference list and vice versa. Corresponding citations must have identical spelling and year.
Authors should update any references to preprints when a peer reviewed version is made available, to cite the published research. Citations to preprints are otherwise discouraged.
If you are including an Acknowledgements section, this will be published at the end of your article. The Acknowledgments section should include all contributors who do not meet the criteria for authorship. Per ICMJE recommendations, it is best practice to obtain consent from non-author contributors who you are acknowledging in your manuscript.
Writing assistance and third party submissions: if you have received any writing or editing assistance from a third-party, for example a specialist communications company, this must be clearly stated in the Acknowledgements section and in the covering letter. Please see the Sage Author Gateway for what information to include in your Acknowledgements section. If your submission is being made on your behalf by someone who is not listed as an author, for example the third-party who provided writing/editing assistance, you must state this in the Acknowledgements and also in your covering letter. Please note that the journal editor reserves the right to not consider submissions made by a third party rather than by the author/s themselves.
This Journal can host additional materials online (e.g. datasets, podcasts, videos, images etc.) alongside the full text of the article. Your supplemental material must be one of our accepted file types. For that list and more information please refer to our guidelines on submitting supplemental files.
Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the journal’s specifications should consider using Sage Author Services. Visit Sage Author Services for further information.
As part of the submission process you will need to confirm that this is your original work, that you have the rights in the work, that this is for first publication in this Journal, that it is not being considered for/has not already been published elsewhere, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you.
Please see our guidelines on prior publication and note that the journal may accept submissions of manuscripts that have been posted on preprint servers.
The journal will consider submissions of manuscripts that have been posted on preprint servers.
Please enter the preprint DOI in the designated field when submitting your manuscript. We advise that you inform the Journal Editorial office about your posted preprint at submission.
Note that you should not post an updated version of your manuscript on a preprint server while it is being peer reviewed.
Submit your manuscript online via Sage Track.
IMPORTANT: Please check whether you already have an account in Sage Track before trying to create a new one. If you have reviewed or authored for the journal in the past year it is likely that you will have had an account created. For further guidance on submitting your manuscript online please visit ScholarOne Online Help.
Manuscripts should only be submitted with the consent of all contributing authors. The individual responsible for submitting the manuscript should carefully check that all those whose work contributed to the manuscript are listed as authors.
Ensure you upload all relevant manuscript files, including any additional supplemental files (including reporting guidelines where relevant).
Please view our authorship policies, which includes information on criteria for authorship, who should be the corresponding author and more.
Please note that AI chatbots, for example ChatGPT, should not be listed as authors. For more information see the policy on Use of ChatGPT and generative AI tools.
The following summary describes the peer review process for this journal:
Identity transparency: Single-anonymized
Reviewer interacts with: Editor
Review information published: None
Your manuscript will undergo an initial evaluation. If it does not conform to the requirements laid out in these guidelines, it will be returned to you for amendments prior to peer review. Manuscripts may be desk rejected without peer review at this point if they are out of scope for the journal or otherwise unsuitable.
After passing the initial evaluation, your manuscript will then be peer reviewed. You can log in at any time to check the status of your manuscript. We will notify you when a decision has been reached.
The journal operates a conventional single-anonymized reviewing policy in which the reviewer’s name is always concealed from the submitting author. Two independent reviews are required for a manuscript to reach a Revise or Accept decision.
To ensure the integrity of the peer review process we assign reviewers and cannot accept author recommendations.
All manuscripts are reviewed as rapidly as possible, while maintaining rigor. Reviewers make comments to the author and recommendations to the Editor who then makes the final decision on all manuscripts, including those appearing in a special issue or special collection. The Editor or members of the Editorial Board may occasionally submit their own manuscripts for possible publication in the Journal. In these cases, the peer review process will be managed by alternative members of the Board and the submitting Editor/Board member will have no involvement in the decision-making process.
As a COPE member we engage with multiple forms of post-publication discussion in line with wider guidance from Sage: Commentaries, Critiques and Responses.
You can view our complaints and appeals policy here.
Read Sage's complete peer review policy.
The journal and Sage take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. Please read Sage's complete policy on plagiarism and the actions we may take.
Before publication, we require the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. Sage’s Journal Contributor’s Publishing Agreement is an exclusive license agreement which means that the author retains copyright in the work but grants Sage the sole and exclusive right and license to publish for the full legal term of copyright. Exceptions may exist where an assignment of copyright is required or preferred by a proprietor other than Sage. In this case copyright in the work will be assigned from the author to the society. For more information please visit the Sage Journal Author Gateway.
If your manuscript was posted on a preprint server prior to acceptance, you must include a link in your preprint to the final published version of your published article.
Your Sage Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will be made available to the corresponding author via our editing portal, Sage Edit, or by email, and should be returned promptly to avoid delaying publication. Authors are reminded to check their proofs carefully to confirm that all author information, including names, affiliations, sequence, and contact details are correct, and that Funding and Conflict of Interest statements, if any, are accurate. This is the final opportunity to make changes to your manuscript. Further corrections will not be possible after publication. Changes to the author list are not permitted at this stage.
OnlineFirst publication: This enables us to publish final articles online immediately, without waiting for assignment to a future issue of the Journal. This usually significantly reduces publication lead time. Visit the Sage Journals help page for more details, including how to cite OnlineFirst articles.
Access to your published article: We provide you with online access to your published article. The online access link is provided to the corresponding author for sharing with their co-authors.
Publication is not the end of the process. Between us, we can ensure that your article is found, read, downloaded and cited as widely as possible. Many of the most effective tactics are those you can do quickly and easily to your network of contacts and peers. Visit the Promote Your Article page on the Sage Journal Author Gateway for numerous resources to help you promote your work.
The Sage Journal Author Gateway has some general advice on how to get published, plus links to further resources. Sage Author Services also offers authors a variety of ways to improve and enhance your article including English language editing, plagiarism detection, and video abstract and infographic preparation.
If you have any questions about publishing with Sage, please visit the Sage Journals Solutions Portal.
You can view our complaints and appeals procedure.
You can direct any questions to the journal’s editorial office: