The only peer-reviewed publication dedicated to the science and applications of gene editing provides a high-profile forum for cutting-edge international original research papers. It also includes a compelling mixture of frontmatter content— review articles, perspectives, profiles, and commentary spanning not only matters of research but the many social, ethical, and business issues confronting the field. The journal centralizes essential information and analysis on this revolutionary technology in a single location with the aim of solidifying and growing the community of innovative researchers, practitioners, policymakers, and activists who make up the field of gene editing.