For cosmetic surgeons, facial augmentation with hyaluronic acid (HA) fillers is a standard and safe technique. We report the case of an unusual allergic reaction to a nasolabial fold augmentation with Restylane-L (a popular HA filler) and review the literature.
Get full access to this article
View all access options for this article.
References
1.
NewmanJ. Review of soft tissue augmentation in the face. Clin Cosmet Investig Dermatol. 2009; 28:141–150.
2.
McCrackenMSKhanJAWulcAE. Hyaluronic acid gel (Restylane) filler for facial rhytids: Lessons learned from American Society of Ophthalmic Plastic and Reconstructive Surgery member treatment of 286 patients. Ophthal Plast Reconstr Surg. 2006; 22:188–191.
3.
RohrichRJGhavamiACrosbyMA. The role of hyaluronic acid fillers (Restylane) in facial cosmetic surgery: Review and technical considerations. Plast Reconstr Surg. 2007;120:41–54.
4.
NarinsRSBrandtFLeydenJLorencZPRubinMSmithS. A randomized, double-blind, multicenter comparison of the efficacy and tolerability of Restylane versus Zyplast for the correction of nasolabial folds. Dermatol Surg. 2003;29:588–595.
FriedmanPMMafongEAKauvarANGeronemusR. Safety data of injectable nonanimal stabilized hyaluronic acid gel for soft tissue augmentation. Dermatol Surg. 2002;28:491–494.
7.
O'ReillyPMalhotraR. Delayed hypersensitivity reaction to Restylane® SubQ. Orbit. 2011;30:54–57.
BellmanB. Immediate and delayed hypersensitivity reactions to Restylane. Aesthet Surg J. 2005;25:489–491.
10.
ShahARWiseJBConstantinidesM. Facial fillers and implants. In: LalwaniAK, ed. CURRENT Diagnosis & Treatment in Otolaryngology—Head & Neck Surgery. 3rd ed.New York, NY: McGraw-Hill; 2012. Available at: http://www.accessmedicine.com/content.aspx?aID=55774468. Accessed October 10, 2012.
11.
SoparkarCNPatrinelyJRSkibellBCTowerRN. Hyaluronidase and Restylane. Arch Facial Plast Surg. 2007;9:299–300.
12.
AlsaadSFabiSGGoldmanMP. Granulomatous reaction to hyaluronic acid: A case series and review of the literature. Dermatol Surg. 2012;38:271–276.
