Abstract
Successful knowledge-based economic models rely on synergy between government, industry and academia. This paper reviews the efforts to convert the island of Puerto Rico from a manufacturing to a high-tech manufacturing/research and development economy with information technology and biotechnology as the main development strongholds. The formation of clusters and partnership between government, industry and academia are essential requirements for successful economies. The strategic approach adopted in Puerto Rico is exemplified by the university-industry partnership developed by the University of Puerto Rico's Industrial Biotechnology programme in cooperation with locally established biotechnology industries.
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