Placental site trophoblastic tumor (PSTT) is a rare variant of gestational trophoblastic tumor (GTN), accounting for 1–2% of all GTNs. Primary testicular PSTTs are extremely rare. Thirty percent of patients with PSTT show multiple lung and brain metastases at the time of diagnosis. We present the first case of a synchronous single pulmonary trophoblastic placental tumor metastasis together with a teratoma and a mixed germinal tumor of the testis, treated with minimally invasive lung metastasectomy.
WentP.T.DirnhoferS.StallmachT.TavernaC.SingerG.Placental site trophoblastic tumor of the mediastinum. Hum Pathol.2005; 36(5): 581–584.
2.
ColeM.E.BroaddusR.ThakerP.LandenC.FreedmanR.S.Placental-site trophoblastic tumors: a case of resistant pulmonary metastasis. Nat Clin Pract Oncol.2008; 5(3): 171–175.
3.
MoranC.A.SusterS.Primary germ cell tumors of the mediastinum: I. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging. Cancer.1997; 80(4): 681–690.
4.
KurmanR.J.ScullyR.E.NorrisH.J.Trophoblastic pseudotumor of the uterus: an exaggerated form of “syncytial endometritis” simulating a malignant tumor. Cancer.1976; 38(3): 1214–1226.
5.
SuurmeijerA.J.GietemaJ.A.HoekstraH.J.Placental site trophoblastic tumor in a late recurrence of a nonseminomatous germ cell tumor of the testis. Am J Surg Pathol.2004; 28(6): 830–833.
6.
ColeM.E.BroaddusR.ThakerP.LandenC.FreedmanR.S.Placental-site trophoblastic tumors: a case of resistant pulmonary metastasis. Nat Clin Pract Oncol.2008; 5(3): 171–175.