We report a case of decidualized endometriosis in pregnancy mimicking ovarian malignancy. Decidualized endometriosis was shown on all histological specimens obtained during laparotomy. We are reporting the highest recorded level of the biomarker Ca125 in pregnancy, in a patient with histologically confirmed decidualized endometriosis.
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References
1.
SherardGBIII, HodsonC.A., WilliamsH.J., SemerD.A., HadiH.A., TaitD.L.Adnexal masses and pregnancy: a 12-year experience. Am J Obstet Gynecol.2003; 189(2): 358–362, discussion 362-363.
2.
GrendysE.C.Jr., BarnesW.A.Ovarian cancer in pregnancy. Surg Clin North Am.1995; 75(1): 1–14.
3.
EskenaziB., WarnerM.L.Epidemiology of endometriosis. Obstet Gynecol Clin North Am.1997; 24(2): 235–258.
4.
BarbieriM., SomiglianaE., OnedaS., OssolaM.W., AcaiaB., FedeleL.Decidualized ovarian endometriosis in pregnancy: a challenging diagnostic entity. Hum Reprod.2009; 24(8): 1818–1824.
5.
TazegülA., Seçilmiş KerimoğluO., IncesuF.N., DoğanN.U., YılmazS.A., CelikC.A case presentation: decidualized endometrioma mimicking ovarian cancer during pregnancy. Case Rep Obstet Gynecol.2013; 2013: 728291.
6.
MachidaS., MatsubaraS., OhwadaM.. Decidualization of ovarian endometriosis during pregnancy mimicking malignancy: report of three cases with a literature review. Gynecol Obstet Invest.2008; 66(4): 241–247.
CovensA.L., DodgeJ.E., LacchettiC.; Gynecology Cancer Disease Site Group. Surgical management of a suspicious adnexal mass: a systematic review. Gynecol Oncol.2012; 126(1): 149–156.
9.
TimmermanD., AmeyeL., FischerovaD.. Simple ultrasound rules to distinguish between benign and malignant adnexal masses before surgery: prospective validation by IOTA group. BMJ.2010; 341: c6839.
HofbauerJ.Decidual formation on the peritoneal surface of the gravid uterus. Am J Obstet Gynecol.1929; 17: 603–612.
12.
MoenM.H., MuusK.M.Endometriosis in pregnant and non-pregnant women at tubal sterilization. Hum Reprod.1991; 6(5): 699–702.
13.
IwamotoH., SuzukiM., WatanabeN., MinaiM., HirataS., HoshiK.Case study of a pregnant woman with decidualized ovarian endometriosis whose pre-operative findings suggested malignant transformation. Eur J Gynaecol Oncol.2006; 27(3): 301–303.
14.
FruscellaE., TestaA.C., FerrandinaG.. Sonographic features of decidualized ovarian endometriosis suspicious for malignancy. Ultrasound Obstet Gynecol.2004; 24(5): 578–580.
15.
MarkmanM., PetersenJ., BellandA., BurgK.CA-125 monitoring in ovarian cancer: patient survey responses to the results of the MRC/EORTC CA-125 Surveillance Trial. Oncology.2010; 78(1): 1–2.
16.
MarkmanM.The CA125 antigen level as a prognostic versus a predictive test in epithelial ovarian cancer. Nat Clin Pract Oncol.2007; 4(11): 628–629.
17.
HanS.N., LotgerinkA., GziriM.M.. Physiologic variations of serum tumor markers in gynecological malignancies during pregnancy: a systematic review. BMC Med.2012; 10: 86.
18.
KobayashiF., TakashimaE., SagawaN., MoriT., FujiiS.Maternal serum CA125 levels in early intrauterine and tubal pregnancies. Arch Gynecol Obstet.1993; 252(4): 185–189.
19.
CheckJ.H., HornsteinM.D.Endometriosis causing very high early first trimester serum CA 125 levels. Int J Gynaecol Obstet.1995; 48(2): 217–218.
20.
SpitzerM., KaushalN., BenjaminF.Maternal CA-125 levels in pregnancy and the puerperium. J Reprod Med.1998; 43(4): 387–392.