Successful treatment of prosthetic joint infections often requires multiple surgical interventions and prolonged antibiotic therapy. However, in some specific situations surgical intervention can not be the treatment of choice. We refer to situations where there is no pain or impairment of the general conditions, involving patients, usually elderly, refusing surgery. In these cases we consider the conservative approach as an option.
PavoniGL, GiannellaM, FalconeM, Conservative medical therapy of prosthetic joint infections: retrospective analysis of an 8-year experience.Clin Microbiol Infect2004; 10:831–7.
2.
SchoifetSD, MorreyBF.Treatment of infection after total knee arthroplasty by debridement with retention of the components.J Bone Joint Surg Br1990; 72: 1383–90.
DrancourtM, SteinA, ArgensonJN, RoironR, GroulierP, RaoultD.Oral treatment of Staphylococcus spp.infected orthopaedic implants with fusidic acid or ofloxacin in combination with rifampicin. J Antimicrob Chemother1997; 39: 235–40.
7.
SteinA, BatailleJF, DrancourtM, Ambulatory treatment of multidrug-resistant Staphylococcus-infected orthopedic implants with high-dose oral cotrimoxazole.Antimicrob Agents Chemother1998; 42: 3086–91.
8.
ZimmerliW, OchsnerPE.Management of infection associated with prosthetic joints.Infection2003; 31: 99–108.
9.
ZimmerliW, WidmerAF, BlatterM, FreiR, OchsnerPE.Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial.Foreign-Body Infection (FBI) Study Group. JAMA1998; 279: 1537–41.
10.
BrandtCM, SistrunkWW, DuffyMC, Staphylococcus aureus prosthetic joint infection treated with debridement and prosthesis retention.Clin Infect Dis1997; 24: 914–9.