Intensive lifestyle intervention has little effect on cardiovascular complications in people with type 2 diabetes

1Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346:393–403.

2 Tuomilehto J Lindström J Eriksson JG Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001; 344:1343–50.

3 Dixon JB Lambert GW. The obesity paradox – a reality that requires explanation and clinical interpretation. Atherosclerosis 2013; 226:47–8.

4 Carnethon MR DeChavez PJ Briggs ML Association of weight status with mortality in adults with incident diabetes. JAMA 2012; 308:581–90.