Zheng Ming C, Sandercock P, Hong Chao P Indications for early aspirin use in acute ischemic stroke: a combined analysis of 40,000 randomized patients from the Chinese Acute Stroke Trial and the International Stroke Trial. Stroke 2000; 31:1240–9. http://dx.doi.org/10.1161/01.STR.31.6.1240
2.
MiddletonSMcElduffPWardJ Implementation of evidencebased treatment protocols to manage fever, hyperglycaemia, and swallowing dysfunction in acute stroke (QASC): a cluster randomised controlled trial. Lancet 2011; 378;1699–706. http://dx.doi.org/10.1016/S0140-6736(11)61485-2
3.
HackeWDonnanGFieschiC Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004; 363:768–74. http://dx.doi.org/10.1016/S0140-6736(04)15692-4
4.
HackeWKasteMBluhmkiE Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008; 359:1317–29. http://dx.doi.org/10.1056/NEJMoa0804656
5.
SaverJL.Number needed to treat estimates incorporating effects over the entire range of clinical outcomes: novel derivation method and application to thrombolytic therapy for acute stroke. Arch Neurol 2004; 61:1066–70. http://dx.doi.org/10.1001/archneur.61.7.1066
6.
WahlgrenNAhmedNDavalosA Thrombolysis with alteplase for acute ischaemic stroke in the Safe implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet 2007; 369:275–82. Erratum in: Lancet 2007; 369:826. http://dx.doi.org/10.1016/S0140-6736(07)60149-4
7.
MishraNKDienerHCLydenPD Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA). Stroke 2010; 41:2840–8. http://dx.doi.org/10.1161/STROKEAHA.110.586206
8.
RhaJHSaverJL.The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 2007; 38:967–73. http://dx.doi.org/10.1161/01.STR.0000258112.14918.24
9.
ParsonsMSprattNBivardA A randomized trial of tenecteplase versus alteplase for acute ischemic stroke. New Engl J Med 2012; 366:1099–107. http://dx.doi.org/10.1056/NEJMoa1109842
10.
FurlanAHigashidaRWechslerL Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA 1999; 282:2003–11. http://dx.doi.org/10.1001/jama.282.21.2003
11.
SaverJLJahanRLevyE Primary results of the SOLITAIRE™ With the Intention for Thrombectomy (SWIFT) multicenter, randomized clinical trial. Dallas: American Heart Association; 2012.
12.
SmithWSSungGSaverJ Mechanical thrombectomy for acute ischemic stroke final results of the Multi MERCI trial. Stroke 2008; 39:1205–12. http://dx.doi.org/10.1161/STROKEAHA.107.497115
13.
MlynashMLansbergMGDe SilvaDA Refining the definition of the malignant profile: insights from the DEFUSE-EPITHET pooled data set. Stroke 2011; 42:1270–5. http://dx.doi.org/10.1161/STROKEAHA.110.601609
14.
LanierWL.Cerebral metabolic rate and hypothermia: their relationship with ischemic neurologic injury. J Neurosurg Anesthesiol 1995; 7:216–21. http://dx.doi.org/10.1097/00008506-199507000-00021
15.
van der Worp HB, Sena ES, Donnan GA Hypothermia in animal models of acute ischaemic stroke: a systematic review and metaanalysis. Brain 2007; 130:3063–74. http://dx.doi.org/10.1093/brain/awm083
16.
MendelowADGregsonBAFernandesHMEarly surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet2005; 365:387–97.
17.
MayerSABrunNCBegtrupK Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. New Engl J Med 2008; 358:2127–37. http://dx.doi.org/10.1056/NEJMoa0707534
18.
HanleyDFLaneKAwadI MISTIE Phase II results: safety, efficacy and surgical performance. Dallas: American Heart Association; 2012.