Abstract
Background:
SARS-CoV-2, a novel coronavirus from the same family as SARS-CoV and Middle East Respiratory Syndrome coronavirus, has overrun worldwide leading the World Health Organization to declare a pandemic. The aim of study was to clarify high-risk factors for COVID-19 with multivariate analysis and establish a predictive model of disease progression to help clinicians better choose a therapeutic strategy. With the latest in technology and research, and further studies into the pathogenesis Evaluate, clinical implications, identification, diagnosis, and treatment of COVID-19 will push society past this pandemic.
Methods:
A comprehensive search of PubMed, MEDLINE, UptoDate, Natural MEDLINE, Embase, and Web of Science electronic databases was made, using the following search terms: COVID-19，COVID-19 SCORE，COVID-19 diagnosis，COVID-19 management, coronavirus, and SARS-CoV-2 as keywords for our search. We included scientific publications from December 1, 2019 to April 30, 2021 which focused on clinical characteristics of and treatments for SARS-CoV-2 were eligible for inclusion. We screened all reference lists of relevant studies in order to identify any missing publications.
Results:
A total of 31 articles. We found that the main symptoms of COVID-19 are fever, cough, fatigue, dyspnea, sore throat, headache, diarrhea, and gastrointestinal issues. Realtime PCR is used as a diagnostic tool using nasal swab, tracheal aspirate or bronchoalveolar lavage samples. Computed tomography findings are important for both diagnosis and follow-up. To date, there is no evidence of any effective treatment for COVID-19.
Conclusions:
Prognosis scores routinely using the COVID score model, this guideline is not to replace clinical professional judgment or expert advice. Even in countries with adequate levels of vaccination, the epidemic could recur if indoor ventilation is not properly addressed. Governments should acknowledge scientific evidence and take steps to develop official regulations and guidelines for indoor space ventilation to reduce the spread of COVID-19.
Symptoms observed in various cohorts of patient
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