Abstract
Background:
An advance in medical technology and increase of old patients with chronic respiratory failure are increasing the prevalence on noninvasive ventilation. This study was done to evaluate the clinic characteristics, outcomes, and prognostic factors of adult patients requiring noninvasive ventilation in a regional hospital.
Methods:
Retrospective chart review was performed on ICU adult patients, who received noninvasive ventilation at Taiwan middle medical center hospital with approximately 200 beds from April, 2017 to March, 2018. We analyzed the characteristics between the weaning success and the weaning failure group. Data were expressed as the number or median. This study was approved by the ethic committee of Canghua Christian Hospital.
Results:
The median age of patients was 60.91 years and 67% were male. The cause of noninvasive ventilation were acute respiratory failure 59.4%, acute exacerbation of chronic respiratory failure 20.6%, and neuromuscular disease 7.3%. Mortality was 10.3% and the patients requiring home BiPAP at discharge were 5.7%. The overall weaning rate from noninvasive ventilation was 73.8% . The weaning success group had a higher heart failure 48.5% and a lower total duration of noninvasive ventilation, median 7.8 days vs 3.2 days, compare to weaning failure group. Total duration on noninvasive ventilation above 5 days, chronic lung disease,and heart failure were independently associated with successful noninvasive ventilation weaning.
Conclusions:
Chronic lung disease, heart failure and duration of noninvasive ventilation appeared to be significantly associated with successful weaning from noninvasive ventilation.
Get full access to this article
View all access options for this article.