The Effect of Intrapulmonary Percussive Ventilation Therapy on Intracranial Pressure in Neurocritical Patients

Abstract

Background:

To measure the effect of intrapulmonary percussive ventilation therapy (IPV) on intracranial pressure (ICP) in patients with neurological injuries and diseases.

Methods:

A retrospective study was conducted on patients (n=25) with ICP monitoring device who received IPV therapies (n=426) by respiratory therapists in Neurocritical Care Unit at University of Utah Health. Hourly values of ICP, mean arterial pressure (MAP), SpO₂ recorded by RNs in the MAR were collected to measure the effect before and after the IPV therapy. Results were expressed as the difference between pre and post values and were averaged per patient.

Results:

25 patients were included, median age 52 (21-68) years. The average ICP changed from 9 to 8, MAP, 90 to 89, yielding no change in cerebral perfusion pressure (CPP) from 81 to 81 (CPP=MAP-ICP). The average SpO₂ remained at 97%. P-Value was 0.017 on ICP with significance level at p < 0.05.

Conclusions:

The IPV therapy decreased the average ICP by 1. There was no significant effect on CPP or SpO₂.

Disclosures:

None.