Research in the area of adult invasive mechanical ventilation is rich and diverse. With more than 3,200 articles on mechanical ventilation published in 2018, isolating the most relevant literature is a challenge. Separated into 5 themes (ie, ventilatory support, hyperoxia, ventilator-associated events, prevention of events, and ventilator liberation), this article will describe the most important papers published on adult invasive mechanical ventilation in 2018.
RotondiAJ, ChelluriL, SirioC, MendelsohnA, SchulzR, BelleS, et al. Patients' recollections of stressful experiences while receiving prolonged mechanical ventilation in an intensive care unit. Crit Care Med, 2002; 30(4):746–752.
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ChahraouiK, LaurentA, BioyA, QuenotJ-P. Psychological experience of patients 3 months after a stay in the intensive care unit: a descriptive and qualitative study. J Crit Care, 2015; 30(3):599–605.
3.
BrowerRG, MatthayMA, MorrisA, SchoenfeldD, ThompsonBT, WheelerA. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med, 2000; 342(18):1301–1308.
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FanE, NeedhamDM, StewartTE. Ventilatory management of acute lung injury and acute respiratory distress syndrome. JAMA, 2005; 294(22):2889–2896.
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PutensenC, TheuerkaufN, ZinserlingJ, WriggeH, PelosiP. Meta-analysis: ventilation strategies and outcomes of the acute respiratory distress syndrome and acute lung injury. Ann Intern Med, 2009; 151(8):566–576.
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NeedhamDM, YangT, DinglasVD, Mendez-TellezPA, ShanholtzC, SevranskyJE, et al. Timing of low tidal volume ventilation and intensive care unit mortality in acute respiratory distress syndrome. A prospective cohort study. Am J Respir Crit Care Med, 2014; 191(2):177–185.
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Writing Group for the PReVENT Investigators. Effect of a low vs intermediate tidal volume strategy on ventilator-free days in intensive care unit patients without ards: a randomized clinical trial. JAMA, 2018; 320(18):1872–1880.
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AmatoMBP, MeadeMO, SlutskyAS, BrochardL, CostaELV, SchoenfeldDA, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med, 2015; 372(8):747–755.
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SchmidtMFS, AmaralACKB, FanE, RubenfeldGD. Driving pressure and hospital mortality in patients without ARDS: a cohort study. Chest, 2018; 153(1):46–54.
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GadreSK, DuggalA, Mireles-CabodevilaE, KrishmanS, WangXF, ZellK, GuzmanJ. Acute respiratory failure requiring mechanical ventilation in severe chronic obstructive pulmonary disease (COPD). Medicine (Baltimore), 2018; 97(17):e0487.
11.
MartinDS, GrocottMPW. Oxygen therapy in critical illness: precise control of arterial oxygenation and permissive hypoxemia. Crit Care Med, 2013; 41(2):423–432.
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AggarwalNR, BrowerRG, HagerDN, ThompsonBT, NetzerG, ShanholtzC, et al. Oxygen exposure resulting in arterial oxygen tensions above the protocol goal was associated with worse clinical outcomes in acute respiratory distress syndrome. Crit Care Med, 2018; 46(4):517–524.
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EgiM, KataokaJ, ItoT, NishidaO, YasudaH, OkamaotoH, et al. Oxygen management in mechanically ventilated patients: a multicenter prospective observational study. J Crit Care, 2018; 46:1–5.
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MagillSS, KlompasM, BalkR, BurnsSM, DeutschmanCS, DiekemaD, et al. Developing a new, national approach to surveillance for ventilator-associated events. Crit Care Med, 2013; 41(11):2467–2475.
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HayashiY, MorisawaK, KlompasM, JonesM, BandesheH, BootsR, et al. Toward improved surveillance: the impact of ventilator-associated complications on length of stay and antibiotic use in patients in intensive care units. Clin Infect Dis Off Publ Infect Dis Soc Am, 2013; 56(4):471–477.
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Klein KlouwenbergPMC, van MourikMSM, OngDSY, HornJ, SchultzMJ, CremerOL, BontenMJM. Electronic implementation of a novel surveillance paradigm for ventilator-associated events. Feasibility and validation. Am J Respir Crit Care Med, 2014; 189(8):947–955.
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KlompasM, AndersonD, TrickW, BabcockH, KerlinMP, LiL, et al. The preventability of ventilator-associated events. The CDC prevention epicenters wake up and breathe collaborative. Am J Respir Crit Care Med, 2014; 191(3):292–301.
18.
BoyerAF, SchoenbergN, BabcockH, McMullenKM, MicekST, KollefMH. A prospective evaluation of ventilator-associated conditions and infection-related ventilator-associated conditions. Chest, 2015; 147(1):68–81.
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KobayashiH, UchinoS, TakinamiM, UezonoS. The impact of ventilator-associated events in critically ill subjects with prolonged mechanical ventilation. Respir Care, 2017; 62(11):1379–1386.
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DanielisM, BenattiS, CelottiP, De MonteA, TrombiniO. Continuous monitoring of endotracheal tube cuff pressure: best practice in intensive care unit. Assist Inferm Ric, 2015; 34(1):15–20.
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LetvinA, KremerP, SilverPC, SamihN, Reed-WattsP, KollefMH. Frequent versus infrequent monitoring of endotracheal tube cuff pressures. Respir Care, 2018; 63(5):495–501.
22.
SottilePD, AlbersD, HigginsC, MckeehanJ, MossMM. The association between ventilator asynchrony, delivered tidal volume, and sedation using a novel automated ventilator asynchrony detection algorithm. Crit Care Med, 2018; 46(2):e151–e157.
23.
de HaroC, López-AguilarJ, MagransR, MontanyaJ, Fernández-GonzaloS, TuronM, et al. Double cycling during mechanical ventilation: frequency, mechanisms, and physiologic implications. Crit Care Med, 2018; 46(9):1385–1392.
24.
SchmidtGA, GirardTD, KressJP, MorrisPE, OuelletteDR, AlhazzaniW, et al. Liberation from mechanical ventilation in critically ill adults: executive summary of an official American College of Chest Physicians/American Thoracic Society clinical practice guideline. Chest, 2017; 151(1):160–165.
25.
KalletRH, ZhuoH, YipV, GomezA, LipnickMS. Spontaneous breathing trials and conservative sedation practices reduce mechanical ventilation duration in subjects with ARDS. Respir Care, 2018; 63(1):1–10.
26.
LiangG, LiuT, ZengY, ShiY, YangW, YangY, KangY. Characteristics of subjects who failed a 120-minute spontaneous breathing trial. Respir Care, 2018; 63(4):388–394.
27.
PerkinsGD, MistryD, GatesS, GoaF, SnelsonC, HartN, et al. Effect of protocolized weaning with early extubation to noninvasive ventilation vs invasive weaning on time to liberation from mechanical ventilation among patients with respiratory failure: the breathe randomized clinical trial. JAMA, 2018; 320(18):1881–1888.
