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Abstract

BACKGROUND:

A correlation has been observed between obstructive sleep events and sleep quality. The aim of the study was to assess if there is also a correlation between nocturnal hypoxemia and hypercapnia and sleep efficiency and sleep fragmentation in children.

METHODS:

Nocturnal pulse oximetry (S_pO₂) and transcutaneous carbon dioxide (P_tcCO₂) recordings with simultaneous actigraphy were performed in 38 children with nocturnal hypoxemia and hypercapnia during spontaneous breathing (nocturnal hypoventilation [NH] group), 25 children with partially corrected nocturnal hypoventilation (PC-NH group), and 11 subjects with normal nocturnal gas exchange (no-NH group).

RESULTS:

Sleep efficiency and sleep fragmentation on actigraphy correlated with minimal S_pO₂ (r² = 0.21, P = .004, and r² = −0.10, P = .050, respectively) and the percentage of night time with S_pO₂ < 90% (r² = −0.33, P < .001, and r² = 0.13, P = .028, respectively) in the NH group. Sleep efficiency and sleep fragmentation also correlated with pulse rate standard deviation (r² = −0.42, P < .001, and r² = 0.37, P < .001, respectively). No correlation was observed between sleep efficiency and sleep fragmentation and P_tcCO₂. No correlation was observed between sleep efficiency and sleep fragmentation and S_pO₂, P_tcCO₂, and pulse rate in the PC-NH group. Sleep efficiency, sleep fragmentation, and nocturnal S_pO₂, and P_tcCO₂ were all normal and not correlated in the no-NH group.

CONCLUSIONS:

In children with nocturnal hypoventilation, nocturnal hypoxemia but not hypercapnia correlates with sleep efficiency and sleep fragmentation on actigraphy.

Keywords

actigraphy child hypoxemia pulse oximetry sleep efficiency sleep fragmentation

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Nocturnal Hypoxemia,But Not Hypercapnia,Correlates With Sleep Quality in Children

Abstract

BACKGROUND:

METHODS:

RESULTS:

CONCLUSIONS:

Keywords

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References