Inflammation and Microbial Translocation in Treatment-Controlled HIV Patients

Bastard J.P. , Soulié C. , Fellahi S. Circulating interleukin-6 levels correlate with residual HIV viraemia and markers of immune dysfunction in treatment-controlled HIV-infected patients. Antivir Ther 2012; 17: 915–919.

Reus S. , Portilla J. , Sánchez-Payá J. Low-level HIV viremia is associated with microbial translocation and inflammation. J Acquir Immune Defic Syndr 2013; 62: 129–134.

Pyne M.T. , Brown K.L. , Hillyard D.R. Evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test and identification of rare polymorphisms potentially affecting assay performance. J Clin Microbiol 2010; 48: 2852–2858.

Such J. , Francés R. , Muñoz C. Detection and identification of bacterial DNA in patients with cirrhosis and culture-negative, nonneutrocytic ascites. Hepatology 2002; 36: 135–141.

Francés R. , González-Navajas J.M. , Zapater P. Translocation of bacterial DNA from gram-positive microorganism is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis. Clin Exp Immunol 2007; 150: 230–237.

Doyle T. , Smith C. , Vitiello P. Plasma HIV-1 RNA detection below 50 copies/ml and risk of virologic rebound in patients receiving highly active antiretroviral therapy. Clin Infect Dis 2012; 54: 724–732.

Henrich T.J. , Wood B.R. , Kuritzkes D.R. Increased risk of virologic rebound in patients on antiviral therapy with a detectable HIV load <48 copies/ml. PLoS ONE 2012; 7: e50065.

Doyle T. , Geretti A.M. Low-level viraemia on HAART: significance and management. Curr Opin Infect Dis 2012; 25: 17–25.