MillsA.M., NelsonM., JayaweeraD.Once-daily darunavir/ritonavir vs lopinavir/ritonavir in treatment-naive, HIV-1-infected patients: 96-week analysis.AIDS2009; 23: 1679–1688.
2.
MadrugaJ.V., BergerD., McMurchieM.Efficacy and safety of darunavir-ritonavir compared with that of lopinavir–ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITIAN: a randomised controlled Phase III trial.Lancet2007; 370: 49–58.
3.
ClotetB., BellosN., MolinaJ.M.Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials.Lancet2007; 369: 1169–1178.
4.
BlancheS., BolognaR., CahnP.Pharmacokinetics, safety and efficacy of darunavir/ritonavir in treatment-experienced children and adolescents.AIDS2009; 23: 2005–2013.
5.
PENTA Steering Committee.PENTA 2009 guidelines for the use of antiretroviral therapy in paediatric HIV-1 infection.HIV Med2009; 10: 591–613.
6.
Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children.Guidelines for the use of antiretroviral agents in pediatric HIV infection; pp. 1–219. (Updated 16 August 2010. Accessed 6 December 2010.) Available from http://aidsinfo.nih.gov/ContentFiles/PediatricGuidelines.pdf.
ViolariA., BolognaR., KimutaiR.ARIEL: 24-week safety and efficacy of DRV/r in treatment-experienced 3 to <6 year old patients.18th Conference on Retroviruses and Opportunistic Infection. 27 February–11 March 2011, Boston, MA, USA. Poster 713.
9.
de MeyerS., VangeneugdenT., Van BaelenB.Resistance profile of darunavir: combined 24-week results from the POWER trials.AIDS Res Hum Retroviruses2008; 24: 379–388.
10.
de MeyerS., DierynckI., LathouwersE.Phenotypic and genotypic determinants of resistance to darunavir: analysis of data from treatment experienced patients in POWER 1, 2, 3 and DUET-1 and 2.Antivir Ther2009; 13 Suppl 3: A33.
11.
De La RosaG., PatteryT., PicchioG., LathouwersE., VillacianJ., Van der BorghtK.Changing prevalence of darunavir resistance-associated mutations (DRV RAMs) in clinical samples received for routine resistance testing: 2003-2009.10th International Congress on Drug Therapy in HIV Infection. 7–11 November 2010, Glasgow, UK. Poster P132.
12.
de MeyerS., DescampsD., Van BaelenB.Confirmation of the negative impact of protease mutations I47V, I54M, T74P AND I84V and the positive impact of protease mutation V82A on virological response to darunavir/ ritonavir.Antivir Ther2009; 14 Suppl 1: A147.
13.
JuddA., DoerholtK., TookeyP.A.Morbidity, mortality, and response to treatment by children in the United Kingdom and Ireland with perinatally acquired HIV infection during 1996–2006: planning for teenage and adult care.Clin Infect Dis2007; 45: 918–924.
14.
JohnsonV.A., Brun-VézinetF., ClotetB.Update of the drug resistance mutations in HIV-1: December 2009.Top HIV Med2010; 18: 156–163.
15.
PillayD., GreenH., MatthiasR.Estimating HIV-1 drug resistance in antiretroviral-treated individuals in the United Kingdom.J Infect Dis2005; 192: 967–973.