Rhabdomyolysis in An HIV-Infected Patient with Impaired Renal Function Concomitantly Treated with Rosuvastatin and Lopinavir/Ritonavir

Abstract

The authors describe an HIV-infected patient with moderate renal failure receiving combination antiretroviral therapy. Because of dyslipidaemia he was initially treated with pravastatin but developed rhabdomyolysis after a switch to rosuvastatin. With this case we illustrate that statins as well as antiretroviral therapy are susceptible to clinical relevant drug–drug or drug–disease interactions. Knowledge of these interactions is important to provide patients with the best possible care.