Macrolide Antibiotics and Calcineurin Inhibitors: Avoiding a Far too Common Drug Interaction in Transplant Patients

Abstract

Get full access to this article

View all access options for this article.

References

Wolter

Wagner

Philipp

Fritschka

. Interaction between FK506 and clarithromycin in a renal transplant patient. Eur J Clin Pharmacol 1994;47 (2):207–8.

Kunicki

Sobieszczaska-Małek

. Pharmacokinetic interaction between tacrolimus and clarithromycin in a heart transplant patient. Ther Drug Monit 2005;27 (1):107–8.

Gómez

Alvarez

Errasti

Acute nephrotoxicity in renal transplant patients treated with clarithromycin. Transplant Proc 1999;31 (6):2250–1.

Olyaei

de Mattos

Bennett

. Immunosuppressant-induced nephropathy. Drug Safety 1999;21 (6):471–88.

Page

2nd Miller

Lindenfeld

. Drug therapy in the heart transplant recipient: part IV: drug-drug interactions. Circulation 2005;111:230–9.

Spicer

Liddle

Chapman

The mechanism of cyclosporine toxicity induced by clarithromycin. Br J Clin Pharmacol 1997;43:194–6.

Lindenfeld

Miller

Shakar

Drug therapy in the heart transplant recipient: part II: immunosuppressive drugs. Circulation 2004;110:3848–65.

Elbarbry

Marfleet

Shoker

. Drug-drug interactions with immunosuppressive agents: review of the in vitro functional assays and role of cytochrome P450 enzymes. Transplantation 2008;85 (9):1222–9.

Strachan

Burton

Pearson

. Is oral azithromycin effective for the treatment of cyclosporine-induced gingival hyperplasia in cardiac transplant recipients? J Clin Pharm Ther 2003;28:329–38.

10.

Ross

Hendry

Dipchand

. 2001 Canadian Cardiovascular Society Consensus Conference on Cardiac Transplantation. Can J Cardiol 2003;19 (6):620–54.