End-stage renal disease patients with cirrhosis represent a therapeutic dilemma, with several difficulties associated with hemodialysis as a renal replacement therapy modality. Peritoneal dialysis is a feasible option for these patients, despite the confounders of associated infection risk, malnutrition, ascites management, and mechanical complications. This review covers the existing data on the outcomes and complications associated with the use of peritoneal dialysis in the cirrhotic patient.
ScaglioneS., KliethermesS., CaoG., ShohamD., DurazoR., LukeA.The epidemiology of cirrhosis in the United States: a population-based study.J Clin Gastroenterol2015; 49(8): 690–6.
4.
DavisG.L., RobertsW.L.The healthcare burden imposed by liver disease in aging baby boomers.Curr Gastroenterol Rep2010; 2(1): 1–6.
5.
LozanoR., NaghaviM., ForemanK., LimS., ShibuyaK., AboyansV.Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.Lancet2012; 380(9859): 2095–128.
6.
ChienC.C., WangJ.J., SunY.M., SunD.P., SheuM.J., WengS.F.Long term-survival and predictors for mortality among dialysis patients in an endemic area for chronic liver disease: a national cohort study in Taiwan.BMC Nephrol2012; 13: 43.
7.
HwangS.J., YangW.C., LinM.Y., MauL.W., ChenH.C.Taiwan Society of Nephrology. Impact of the clinical conditions at dialysis initiation on mortality in incident haemodialysis patients: a national cohort study in Taiwan.Nephrol Dial Transplant2010; 25(8): 2616–24.
8.
WilkinsonS.P., WestonM.J., ParsonsV., WilliamsR.Dialysis in the treatment of renal failure in patients with liver disease.Clin Nephrol1977; 8(1): 287–92.
9.
MarcusR.G., MessanaJ., SwartzR.Peritoneal dialysis in end-stage renal disease in patients with preexisting chronic liver disease and ascites.Am J Med1992; 93: 35–40.
10.
BajoM.A., SelgasR., JimenezC., Del PesoG., Fernandez-ReyesM.J., DapenaF.CAPD for treatment of ESRD patients with ascites secondary to liver cirrhosis.Adv Perit Dial1994; 10: 73–6.
11.
MartinP.Y., GinesP., SchrierR.W.Nitric oxide as a mediator of hemodynamic abnormalities and sodium and water retention in cirrhosis.N Engl J Med1998; 339: 533–41.
12.
YokokawaK., MankusR., SaklayenM.G., KohnoM., YasunariK., MinamiM.Increased nitric oxide production in patients with hypotension during dialysis.Ann Intern Med1995; 123(1): 35–7.
13.
DonovanJ.P., ScaferD.F., ShawB.W., SorrellM.F.Cerebral oedema and increased intracranial pressure in chronic liver disease.Lancet1998; 351(9104): 719–21.
14.
WinneyR.J., KeanD.M., BestJ.J., SmithM.A.Changes in brain water with hemodialysis.Lancet1986; 2: 1107–8.
15.
GandhiV.C., LeeheyD.J., StanelyM.M., NemchauskyB.A., DaugirdasJ.T., GreenleeH.B.Peritoneo-venous shunting in patients with cirrhotic ascites and end-stage renal failure.Am J Kidney Dis1985; 6(3): 185–7.
16.
ChaudharyK., KhannaR.Renal replacement therapy in end-stage renal disease patients with chronic liver disease and ascites: role of peritoneal dialysis.Perit Dial Int2008; 28: 113–7.
17.
DeVecchiA.F., ColucciP., SalernoF., ScalamognaA., PonticelliC.Outcome of peritoneal dialysis in cirrhotic patients with chronic renal failure.Am J Kidney Dis2002; 40: 161–8.
18.
ChowK.M., SzetoC.C., WuA.K.L., LeungC.B., KwanB.C., LiP.K.Continuous ambulatory peritoneal dialysis in patients with hepatitis B liver disease.Perit Dial Int2006; 26(2): 213–7.
19.
HuangS.T., ChuangY.W., ChengC.H., WuM.J., ChenC.H., YuT.M.Outcome of peritoneal dialysis in cirrhotic patients with end-stage renal disease—a 24 years’ experience in Taiwan.Clin Nephrol2011; 76(4): 306–13.
20.
ChouC.Y., WangS.M., LiangC.C., ChangC.T., LiuJ.H., WangI.K.Peritoneal dialysis is associated with a better survival in cirrhotic patients with chronic kidney disease.Medicine2016; 95(4): e2465.
21.
LeeS.M., SonY.K., KimS.E., AnW.S.Clinical outcomes of peritoneal dialysis in end-stage renal disease patients with liver cirrhosis: a propensity score matching study.Perit Dial Int2017; 37(3): 314–20.
22.
GuestS.Peritoneal dialysis in patients with cirrhosis and ascites.Adv Perit Dial2010; 26: 82–7.
23.
Von GraevenitzA., AmsterdamD.Microbiological aspects of peritonitis associated with continuous ambulatory peritoneal dialysis.Clin Microbiol Rev1992; 5: 36–48.
RunyonB.A., AASLD. Introduction to the revised American Association for the Study of Liver Disease Practice Guideline, management of adult patients with ascites due to cirrhosis 2012.Hepatology2013; 57(4): 1651–3.
