In a double-blind protocol, ninety healthy volunteer subjects received 30 minutes of constant current sine-wave cranial transcutaneous electrical nerve stimulation (TENS) of 5 Hertz (Hz), 100 Hz, or 2000 Hz frequency (current maintained below.5 mA for safety), placebo TENS, or no treatment. The five groups were compared on pre- to posttreatment changes in blood pressure, heart rate, peripheral temperature, and anxiety. Analysis showed significant reductions in systolic and diastolic blood pressure and heart rate after 100 Hz cranial TENS as compared to the other groups. No other differences achieved significance.
TaylorD.N.LeeC.T.KatimsJ. J., & NgL.K.The effects of cranial TENS on measures of autonomic, somatic and cognitive activity. Acupuncture & Electro-Therapeutics Research.Vol. 14, 29–42, 1989.
2.
TaylorD.N.LeeC.T.KatimsAJ.J., Effects of cranial transcutaneous electrical nerve stimulation in normal subjects at rest and during stress. Acupuncture & Electrotherapeutics Research, Int. J., Vol. 16, 65–74, 1992.
3.
KatimsJ.J., & NgL.K.Transcutaneous electrical nerve stimulation (TNS) frequency dependent increases in rat brain metabolic activity. Acupuncture & Electrotherapeutics Research, Int. J., Vol. 10, 223–224, 1985.
4.
OmuraY.Patho-physiology of acupuncture treatment: Effects of Acupuncture on cardiovascular and nervous systems. Acupuncture & Electro-Therapeutics Research Int, J., Vol. 1, 51–141, 1975.
5.
OmuraY.SmithM.WongF.AppfelF.TaftR.Nyint-MintzT.GeeJ.MehtaC.LefkowitzJ., & MurphyR.Electro-acupuncture for drug addiction withdrawal syndrome, particularly methadone, & individualized acupuncture treatments for the withdrawal syndromes of drug addictions and compulsive habits of excessive eating, drinking alcohol, and smoking. Acupuncture & Electro-Therapeutics Research, Int. J., Vol. 1, 231–233, 1975.
6.
OmuraY.Basic electrical parameters for safe and effective electrotherapeutics (electro-acupuncture, TES, TENMS (or TEMS), TENS and electro-magnetic field stimulation with or without drug field) for pain, neuromuscular skeletal problems, and circulatory disturbances. Acupuncture & Electro-Therapeutics Research. Int. J., Vol. 12, 201–225, 1987.
7.
OmuraY.LoscoBrother M., OmuraA.K., TakeshigeC., HisamitsuT., ShimotsuuraY., YamamotoF., IshikawaH., MutekiT., NakajimaH., & UrichC., Common factors contributing to intractable pain and medical problems with insufficient drug uptake in areas to be treated, and their pathogenesis and treatment: Part I. Combined use of medication with acupuncture, + Qi Gong energy-stored material, soft laser or electrical stimulation. Acupuncture & Electro-Therapeutics Research, Int. J., Vol. 17, 107–148, 1992.
8.
SpielbergerC.D.GorsuchR.L.LusheneAR.E., Manual for the State-Trait Anxiety Inventory. Consulting Psychologists Press, Palo Alto, Ca., 1970.
9.
FergusonG.A.Statistical Analysis in Psychology and Education. McGraw-Hill, New York, 1971.
10.
StubbsD.F.Frequency and the brain. Life Sciences.Vol. 18, 1–14, 1976.
11.
KatimsJ.J.LongD.M.4 Ng, L.K.Y., Transcutaneous electrical nerve stimulation: Frequency and waveform specificity in humans. Applied Neurophysiology. Vol. 49, 86–91, 1986.
12.
DymondA. M.CogerR. W., & SerafetinidesE. A.Intracerebral current levels in man during electrosleep therapy. Biological Psychiatry.Vol. 10, 101–104, 1975.
13.
NgL.K.Y.DouthittT.ThoaT.B., & AlbertC.Modification of morphine-withdrawal syndrome in rats following transauricular electrostimulation: an experimental paradigm for auricular electroacupuncture. Biological Psychiatry.Vol. 10, 575–580, 1975.
14.
PertA.DionneR.NgL.K.Y.BraginE.MoodyT. 4 PertC.B., Alterations in rat central nervous system endorphins following transauricular electroacupuncture. Brain Research.Vol. 224, 83–94, 1981.
15.
SalarG.JobI.MingrinoS.BosioA.4 Trabucci, M., Effect of transcutaneous electrotherapy on CSF B-Endorphin content in patients without pain problems. Pain, Vol. 10, 169–172, 1981.
FieldsW.R.TackeR.B., & SavaraB.S.Pulpal anodal blockade of trigeminal field potentials elicited by tooth stimulation in the cat. Experimental Neurology.Vol. 47, 229–239, 1975.
20.
HokfeltT.LjungdahlA.TereniusL.EldeR. 4 NilssonG., Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: Enkephalin and substance P. Proceedings of the National Academy of Science.Vol. 74, 3081–3085, 1977.
21.
BelluzziJ.D. 4 SteinL., Enkephalin may mediate euphoria and drive-reduction reward. Nature.Vol. 226, 556–558, 1977.
22.
RichardsonD.E. 4 AkilH., Pain reduction by electrical brain stimulation in man. Journal of Neurosurgery.Vol. 47, 184–194, 1977.
