Abstract
Objective
To explore the early warning signs of deterioration of patients with COVID-19.
Methods
The data of thirty-six patients who were admitted to Handan Infectious Disease Hospital was collected. The clinical features and laboratory testing were analyzed retrospectively. The initial laboratory testing included blood chemistries, blood routine, D-dimer, coagulation function, etc. The patients were divided into mild/common group and severe/critical group.
Results
The lymphocyte count, monocyte count, hemoglobin, and albumin levels in severe/critical group were lower compared with those in mild/common group, while the fibrinogen was higher. The lymphocyte count and monocyte count were positively correlated with hemoglobin, pre-albumin respectively.
Conclusion
In conclusion, patients with lower initial prealbumin and hemoglobin level were more likely to progress into severe conditions. Decreased prealbumin and hemoglobin, combined with lymphocyte count and monocyte count, could be the early warning signs of deterioration of patients with COVID-19.
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