Objective: The resonance frequency (Fr) of twelve meridians was observed by means of sweep frequency of weak constant current, and a method of evaluating Fr was explored. Method: Four-electrode bioimpedance spectroscopy was used in the study. Constant current of 1~100Hz was applied from a phase-locked amplifier through the excitation electrode to the twelve meridians of 30 healthy subjects. Data were collected by the test electrode and the Fr of the twelve meridians was obtained by data fitting in Matlab. Result: Among the twelve meridians, the Fr of the small intestine meridian is the lowest, and the gallbladder meridian is the highest, which are 23.18±0.99Hz and 28.27±1.39 Hz, respectively. The mean resonance frequencies of meridians of the same name on hand and foot are 24.80±1.34Hz and 26.22±1.17Hz, respectively. The Fr of the Shao Yin meridian of the hands and feet is basically equal, the other five pairs of foot meridians are all higher than the hand meridian, and the difference of the Yang meridian of the same name is greater than the Yin meridian of the same name, the Fr of hand Shao Yang meridian, hand Tai Yang meridian and hand Yang Ming meridian were lower than those of foot meridians. The mean value of 6 pairs of yin and yang meridians are 25.59 ± 1.97Hz and 25.42 ± 0.70Hz, respectively. Conclusion: The resonance frequencies of the twelve meridians ranged from 23 to 28Hz approximately.
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