Human Papilloma Virus-Type 16 (HPV-16) & Human Herpes Virus-Type 8 (HHV-8) infections were found to be co-existing major cancer-contributing factors. Individualized,safe,effective treatment of hopelessly advanced cancer patients with metastasis by combining 4 methods of effective treatment: 1) Optimal dose of Vitamin D3 using its 10 unique beneficial effects,2) Selective Drug Uptake Enhancement Method,3) Stimulation of newly discovered Thymus gland representation areas on the back of each hand,& 4) Identification & removal of co-existing cancer-contributing factors
Restricted accessResearch articleFirst published online August, 2018
Human Papilloma Virus-Type 16 (HPV-16) & Human Herpes Virus-Type 8 (HHV-8) infections were found to be co-existing major cancer-contributing factors. Individualized,safe,effective treatment of hopelessly advanced cancer patients with metastasis by combining 4 methods of effective treatment: 1) Optimal dose of Vitamin D3 using its 10 unique beneficial effects,2) Selective Drug Uptake Enhancement Method,3) Stimulation of newly discovered Thymus gland representation areas on the back of each hand,& 4) Identification & removal of co-existing cancer-contributing factors
Previous study indicated Human Papilloma Virus-Type 16 (HPV-16) has important role in genesis of ovarian cancer, uterus cancer, & breast cancer. Omura, Y. noticed HPV-16 virus co-exists with single-cell parasite Toxoplasma Gondii (T.G.) infection in most of the cancer tissues he examined. Therefore, he thought some unknown virus must exist in the T.G. In early 2018, he found there is strong Human Herpes Virus-Type 8 (HHV-8) infection in every cell of Toxoplasma Gondii he examined. Thus, we found in every cancer cells there are co-existing cancer-promoting factors of HPV-16 & HHV-8 infection associated with Toxoplasma Gondii. As a common source of these infections in human cancer patients, we found most egg yolk has co-existing HPV-16, HHV-8 & Toxoplasma Gondii, but egg whites are free of these infections & can be eaten safely as protein supply. Many cats and dogs also have these infections. As most important, safe treatment of cancer, we found repeated optimal dose of Vitamin D3 with optimal interval of about 8 hours is ideal because of 10 unique, beneficial effects discovered by him. Individually determined one optimal dose of Vitamin D3 has most effective anti-cancer effects in hopeless, advanced, cancer patients by reducing extremely high Integrin α5β1 of over 1500ng to normal value of 0.002~0.004ng and 8-OH-dG (proportional to DNA mutation which is required for cancer growth) of over 60~80ng to normal value of 0.1~0.25ng for average 8 hours and 6000~9000ng of strong pathogenic infection of HPV-16 & HHV-8 in cancer tissue reduced to safe range of less than 500ng by markedly increased urinary excretion. Concerning beneficial effect of optimal dose of Vitamin D3, all the previous studies failed to use individualized optimal dose. As a result, they could not properly evaluate beneficial effects & side effects and many reports claimed there were no significant beneficial effects including anti-cancer effects. Although optimal dose of Vitamin D3 can eliminate these viral infections very significantly but not less than 500~300ng. Cancer incidence is only significant when these viruses are above 6000ng inside the body. Thus, we can keep potentially serious patients with strong cancer-contributing virus infections at relatively safe low degree of infection of much less than 3000ng. Our ideal treatment for advanced cancer patients is a combination of 1) Individually determined Optimal dose of Vitamin D3 with optimal interval of about 8 hours, 2) Selective Drug Uptake Enhancement Method by manual stimulation organ representation area of pathological organs at hands, 3) Stimulation of Thymus gland representation area of the back of the hand which was discovered by Omura, Y. in 2017, & 4) Identification & removal of multiple co-existing cancer- promoting factors. This combination of 4 new methods of treatment was found to be most effective & safe treatment for not only hopelessly advanced cancer patients but also many other difficult medical problems.
OmuraY.“Effects of acupuncture on micro-circulatory system and blood chemistry, and their clinical application.”at the invitation of the Ministry of Health and the President of the Chinese Medical Association of the People's Republic of China with all the expenses paid by the Chinese government for the First Acupuncture Symposia held in Peking during June1–5, 1979, 8 page article published in the Proceedings of the National Symposia of Acupuncture, Moxibustion, and Acupuncture Anesthesia, Beijing, People's Republic of China, 1979.
2.
OmuraY.“Electro-acupuncture: Its electro-physiological basis and criteria for safety and effectiveness, and measurement of threshold potentials for 'tingling', muscle contraction, and pain.”at the invitation of the Ministry of Health and the President of the Chinese Medical Association of the People's Republic of China with all the expenses paid by the Chinese government for the First Acupuncture Symposia held in Peking during June1–5, 1979, 8 page article published in the Proceedings of the National Symposia of Acupuncture, Moxibustion, and Acupuncture Anesthesia, Beijing, People's Republic of China, 1979.
3.
OmuraY.“Simple non-invasive methods of evaluating brain circulation, and the hypotensive and serum lipid lowering effects of acupuncture”, pp. 449-459, Prophylactic Approach to Hypertensive Diseases: Perspectives in Cardiovascular Research: Volume 4, (Book sponsored by NIH) ed. by YamoriY., LovenbergW., & FreisE.D., Raven Press Books Ltd., N.Y.C., U.S.A., 1979.
4.
OmuraY.NisterukC.Losco BroM., DreschnackP. “Minute Notches and Slurring Appearing in the QRS Complexes of ECG's of Humans and Animals (Following Experimentally Induced Minute Myocardial Abnormalities).” pp.154–160, Progress in Electrocardiology, ed. by P.W. Macfarlane, Pitman Medical Press, London, 1979 and G.K. Hall & Co., Boston, Mass., U.S.A., 1981.
5.
OmuraY.Editorial: “Hypertension–Part I: “Lower Extremity Hypertension Syndrome” and Electro-Acupuncture.” in Acupuncture and Electro-Therapeutics Research, The International Journal, Vol. 5, pp. 215–249, 1980.
6.
OmuraY.NisterukC.J.Losco BroM., HellerS.I., HorowitzS. “Minute notches and slurrings in QRS complexes of ECG's of intrinsic myocardial origins as early diagnostic signs of myocardial diseases and their relationship to lower extremity hypertension syndrome (LEHS).” presented at the 7th International Congress on Electro-cardiology in Lisbon, Portugal, June15–19, 1980 published in Proceedings of the 7th International Congress on Electro-cardiology, in Lisbon, Portugal, 1980.
7.
OmuraY.Editorial: “Simple custom-made disposable surface electrode system for non-invasive “electro-acupuncture” or TNS and its clinical applications including treatment of cephalic hypertension and hypotension syndromes as well as temporo- mandibular joint problems, tinnitus, shoulder and lower back pain, etc.” Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 6: pp. 109–134, 1981.
8.
OmuraY.HellerS.I.NisterukC.J.Losco BroM., CookA.W., MeyerE. “Cephalic Hypertension or Lower Extremity Hypertension Found in Individuals with Normal or Low Brachial Arterial Blood Pressure With or Without Anti-Hypertensive Treatment.” p. 848 in Abstracts of the Eighth International Congress of Pharmacology, Tokyo, Japan, July 19-24, 1981.
9.
OmuraY.Editorial: “Effects of an electrical field and its polarity on an abnormal part of the body or organ representation point associated with a diseased internal organ, and its influence on the “Bi-Digital O-Ring Test” (simple, non-invasive dysfunction localization method) & drug compatibility test – Part 1.” Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 7: pp. 209–246, 1982.
10.
OmuraY.NisterukC.J.Losco BroM., HellerS.I., OmuraA., CookA., Williams G. “Non-invasive early diagnosis of cardiovascular diseases by the combined use of the 'Bi-Digital O-Ring Dysfunction Localization Method' organ representation points & minute notches & slurrings appearing in QRS complexes of wide frequency bandwidth ECG's & 'Selective High Frequency Wide Bandwidth ECG's'.” Proceedings of the 9th International Congress on Electrocardiology, held Tokyo, Japan during June 7–11, 1982.
11.
OmuraY.“Wirkungen der Hand-und Elektroakupunktur auf das Kreislauf-system und die Chemie des Blutes. Einfache fruhdiagnostische Methoden und ihre klinische Anwendung”, [“Effects of Manual and Electro-Acupuncture on the Circulatory System and Blood Chemistries, and New Simple Early Diagnostic Methods and Their Clinical Applications,”] International Congress on Acupuncture in Clinic and Research, held in Mainz, West Germany, Sept 30-Oct. 3,1981, Akupunktur Theorie Und Praxix, Vol. 10: No. 2, pp. 200–211, 1982.
12.
OmuraY.Editorial: “Non-invasive circulatory evaluation and electro-acupuncture & TES treatment of diseases difficult to treat in Western medicine: 1) abnormal brain circulation and blood pressure: Cephalic Hypertension or Cephalic Hypotension Syndromes and their related conditions– headache, insomnia, blindness due to macular degeneration & retinitis pigmentosa, and some psychiatric problems; 2) severe lower extremity circulatory disturbances, with intractable pain, intermittent claudication, ulceration and/or severe diabetic neuropathy.” Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 8: pp. 177–255, 1983.
13.
OmuraY.Electro Acupuntura Y Acupuntura Manual, Bases Biofisicas Y Bioquimicas (187 pg. Spanish book), translated into Spanish by Prof.RodriguezH., of Dept. of Medicine, University of Zulia, Maracaibo, published by Edad S.A., Maracaibo, Venezuela, 1983.
14.
OmuraY.“A new, simple, non-invasive imaging technique of internal organs and various cancer tissues using extended principles of the “Bi-Digital O-Ring Test”without using expensive imaging instruments or exposing the patient to any undesirable radiation – Part 1.“ Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 10: pp. 255–277, 1985.
15.
OmuraY.NisterukC.Losco BroM., HellerS., OmuraA., CookA., SpenceD., WilliamsG., LoubserP. “The fine structures of the P-Wave, P-Q Interval and the QRS- Complex of the ECG, found by the use of selective high frequency wide bandwidth oscilloscopic ECG recordings.” pp.143–147 in Advances in Electrocardiology, ed. by P. D'Alche, Centre de Publications de l'Universite de Caen, France, 1985.
16.
OmuraY.“'Bi-Digital O-Ring Test Molecular Identification and Localization Method' and its application in imaging of internal organs and malignant tumors as well as identification and localization of neurotransmitters and micro-organisms – Part 1.”Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 11: No. 2, pp. 65–100, 1986.
17.
OmuraY.“Electro-magnetic resonance phenomenon as a possible mechanism related to the “Bi-Digital O-Ring Test Molecular Identification and Localization Method.”Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 11: No. 2, pp. 127–145, 1986.
18.
OmuraY.Practice of “Bi-Digital O-Ring Test” (191 printed page book in Japanese), Ido-No-Nippon-Sha, Tokyo & Yokosuka, Japan, 1st Ed.,1986.
19.
OmuraY.“Re-evaluation of the classical acupuncture concept of meridians in oriental medicine by the new method of detecting meridian-like networks connected to internal organs using “Bi-Digital O-Ring Test.”Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 11: pp. 219–231, 1986.
20.
OmuraY.“Interrelationship between the heart and central nervous system: localization of neuro-transmitters and imaging of their associated nuclei, including the raphe nuclei & the locus coeruleus, as well as the imaging of the heart and its representation areas in slices of the human central nervous system using the “Bi-Digital O-Ring Test”imaging method.“ Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 12: pp. 139–170, 1987.
21.
OmuraY.“Meridian-like networks of internal organs, corresponding to traditional Chinese 12 main meridians and their acupuncture points as detected by the “Bi-Digital O-Ring Test Imaging Method:”Search for the corresponding internal organ of western medicine for each meridian – Part 1.“ Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 12: pp. 53–70, 1987.
22.
OmuraY.“Microbial infection or trauma at cardiovascular representation area of medulla oblongata as some of the possible causes of hypertension or hypotension.”Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 13: pp. 131–145, 1988.
23.
OmuraY.TakeshigeC.ShimotsuuraY.SuzukiM.“Imaging of the stomach and localization of the stomach meridian & its acupuncture points in a human cadaver by the use of the indirect “Bi-Digital O-Ring Test Imaging Technique.”Acupuncture & Electro- Therapeutics Research, The International Journal., Vol. 13: pp. 153–164, 1988.
24.
OmuraY.“Connections found between each meridian (heart, stomach, triple burner, etc.) & organ representation area of corresponding internal organs in each side of the cerebral cortex; release of common neurotransmitters and hormones unique to each meridian and corresponding acupuncture point & internal organ after acupuncture, electrical stimulation, mechanical stimulation (including shiatsu), soft laser stimulation or Qi Gong.”Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 14: pp. 155–186, 1989.
25.
OmuraY.“Simple Non-Invasive Early Detection and Localization of Specific Cancer Tissues of Internal Organs and Differentiation of Cancer Tissue from Surrounding Areas Infected by Cancer Related Riruses, as well as Evaluation of their Micro-Circulatory Condition & Drug Uptake Using the Bi-Digital O-Ring Test”. Acupuncture & Electro- Therapeutics Research:15 (3-4). pgs. 217–233, 1990.
26.
OmuraY.“Storing of Qi Gong energy in various materials and drugs (Qi Gongnization): its clinical application for treatment of pain, circulatory disturbance, bacterial or viral infections, heavy metal deposits, and related intractable medical problems by selectively enhancing circulation and drug uptake.” Acupuncture & Electro-Therapeutics Research, The International Journal. Vol 15: 137–157, 1990.
27.
OmuraY.LoscoM.OmuraA.YamamotoS.IshikawaH.TakeshigeC.ShimotsuuraY.MutekiT.“Chronic or intractable medical problems associated with prolonged exposure to unsuspected harmful environmental electric, magnetic or electro-magnetic fields radiating in the bedroom or workplace and their exacerbation by intake of harmful light and heavy metals from common sources.” Acupuncture & Electro-Therapeutics Research, The International Journal, Vol 16: No. 3 & 4, pp. 143–177, 1991.
28.
OmuraY.Losco BroM., OmuraA.K., TakeshigeC., HisamitsuT., ShimotsuuraY., YamamotoS., IshikawaH., MutekiT., NakajimaH., UrichC. “Common factors contributing to intractable pain and medical problems with insufficient drug uptake in areas to be treated, and their pathogenesis and treatment: Part I. Combined use of medication with acupuncture, (+) Qi Gong energy-stored material, soft laser or electrical stimulation.” Acupuncture & Electro-Therapeutic Research, The International Journal.,Vol 17: No.2, pp. 107–148, 1992.
29.
OmuraY.Losco BroM., OmuraA.K., YamamotoS., IshikawaH., TakeshigeC., WatariN., NakajimaH., MatsubaraT. “Bi-Directional transmission of molecular information by photons or electron beams passing in the close vicinity of specific molecules, and its clinical and basic research applications: 1) Diagnosis of humans or animal patients without any direct contact; 2) light microscopic and electron microscopic localization of neuro-transmitters, heavy metals, Oncogen C-fos (Ab2), etc. of intracellular fine structures of normal and abnormal single cells using light or electron-microscopic indirect Bi-Digital O-Ring Test.” Acupuncture & Electro- Therapeutics Research, The International Journal. Vol 17: No. 1, pp. 29–46, 1992.
30.
OmuraY.“Bi-Digital O-Ring Test for Imaging and Diagnosing of Internal Organs of a Patient: U.S. Cl.128–630“. United States Patent. 1993.
31.
OmuraY.“Effect of electrical stimulation, Qi Gong or 60 Hz electrical field on acetylcholine & circulation of exposed parts of the body, as well as on insomnia & short term memory, and evaluation & treatment of alzheimer's disease by the use of the Bi-Digital O-Ring Test.”Program & Abstracts of 1st International Symposium on the Bi-Digital O-Ring Test organized by the Japan Bi-Digital O-Ring Test Assoc. and held at Waseda University, International Conference Center, Tokyo, Japan, pp. 66–67, May 7-9, 1993.
32.
OmuraY.Losco, Bro. M. “Electro-magnetic fields in the home environment (color TV, computer monitor, microwave oven, cellular phone, etc.) as potential contributing factors for the induction of Oncogen C-fos Ab1, Oncogen C-fos Ab2, Integrin α5 α1 and development of cancer, as well as effects of microwave on amino acid composition of food and living human brain.” Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 18, No. 1, pp. 33–73, 1993.
33.
OmuraY.IshidaY.“Search for the Mechanism of Bio-Sensor: When Given Medication is Ineffective what do You Suspect? How do you Identify Whether Drug is Reaching the Pathological Area to be Treated? How do You Judge the Drug-Drug Interaction? Listen to the Originator of the Bi-Digital O-Ring Test, Yoshiaki Omura.”Sawarabi. (Japanese Quarterly Medical Journal Published by Medical Review Publishing Co., Osaka, Japan) No. 18, pp. 30–36, April 1, 1994.
34.
OmuraY.“Transmission of molecular information through electro-magnetic waves with different frequencies and its application to non-invasive diagnosis of patients as well as detection from patient's x-ray film of visible and not visible medical information: part 1.”Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 19, No. 1, pp. 39–63, 1994.
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OmuraY.Practice of “Bi-Digital O-Ring Test”. (195 printed page book in Japanese.) Ido-No-Nippon-Sha, Tokyo & Yokusuko, Japan, 4th printing of 5th Edition, January2005.
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OmuraY.KodamaH.Future Medicine O-Ring Test (341 printed pages in Japanese), Ido-No- Nippon-sha, Tokyo, Japan, 2008 (9th printing). ISBN: 978-4-7529-5044-8.
39.
OmuraY.How to Detect Diseases From the Human Face: Clinical Application of O- Ring Test (223 printed page book in Japanese.) Bunge-Sha, Tokyo, Japan,2012. ISBN: 978–4-286-12835-1.
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OmuraY.JonesK.M., NiharanA., DuvviH., ShimotsuuraY., OhkiM. “More than 97% of Human Papilloma Virus Type 16 (HPV-16) was Found with Chrysotile Asbestos & Relatively Smooth Round Tumor Outline, and Less than 3% was found with HPV - 18 and Tremolite Asbestos & Irregular Sawtooth-like Zigzag Outline in Breast Cancer Tissues in Over 500 Mammograms of Female Patients: Their Implications in Diagnosis, Treatment, and Prevention of Breast Cancer.” Acupuncture & Electro-Therapeutics Research, International Journal of Integrated Medicine;38 (3-4) pp. 211–230, 2013.
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OmuraY.Promotion of Health & Longevity by stimulation of Organ Representation Areas of Hands. (Revised 2nd Edition 207-page book written in Japanese) Makino Publishing Co., Tokyo, Japan March2015.
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OmuraY.“Clinical Implications of the HPV-16 Infection & 7 Beneficial Effects of Optimal Dose of Vitamin D3 in Safe, Effective Cancer Treatment: Non-invasive Rapid Cancer Screening using 'Mouth, Hand & Foot Writing Form' of 40 participants during 150-minute Workshop on The Bi-Digital O-Ring Test, in The 1st Day of European Congress for Integrative Medicine, September 9-11, 2016 in Budapest.” Vol. 41, No. 3/4, pgs. 171–198, 2016.
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