Glynn RJ, Field TS, Rosner B. et al. Evidence for a positive relation between blood pressure and mortality in elderly people. Lancet1995;345:825-9.
2.
Reynolds E., Baron RBHypertension in women and the elderly. Some puzzling and some expected findings of treatment studies. Postgrad Med1996;100:58-70.
3.
BurtVL,Whelton P., Roccella EJ et al. Prevalence of hypertension in the US adult population: results from the third National Health and Nutrition Survey, 1988-1991. Hypertension1995;25:305-13.
4.
Hyman DJ, Pavlik VNCharacteristics of patients with uncontrolled hypertension in the United States . N Engl J Med2001;345:479-86.
5.
National High Blood Pressure Education Program Working Group.National High Blood Pressure Education Program Working Group Report on Hypertension in the Elderly. Hypertension1994;23:275-85.
6.
Insua JT, Sacks HS, Lau TS et al. Drug treatment of hypertension in the elderly: a meta-analysis . Ann Intern Med1994;121:355-62.
7.
European Working Party on High Blood Pressure in the Elderly Group.Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly Trial. Lancet1985;1:1349-54.
8.
SHEP Cooperative Research Group.Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension.JAMA1991 ;265:3255-64.
9.
Dahlof B., Lindholm LH, Hansson L. et al. Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension. Lancet1991;338:1281-5.
10.
MRC Working Party.Medical Research Council of treatment of hypertension in older adults : principal results. BMJ1992 ;304:405-12.
11.
Staessen JA , Fagard R.,Thijs L. et al. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet1997;350: 757-64.
12.
Gueyffier F. , Bulpitt C., Boissel JP et al. Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. INDANA Group . Lancet1999;353:793-6.
13.
Collins R., Peto R., Mac Mahon S. et al. Blood pressure, stroke and coronary heart disease. Part 2, short term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet1990;335:827-38.
14.
Safar METherapeutic trials and large arteries in hypertension. Am Heart J1988;115:702-10.
15.
Society of actuaries. Build and blood pressure study. 1959. Chicago, III: Society of Actuaries ; 1959.
16.
Stamler J., Neaton JD, Wentworth DNBlood pressure (systolic and diastolic) and risk of fatal coronary heart disease . Hypertension1989;13:2-12.
17.
Black HRThe paradigm has shifted to systolic blood pressure. Hypertension1999; 34:386-7.
18.
Darné B., Girerd X., Safar M., Cambien F., Guize L.Pulsatile versus steady component of blood pressure. A cross-sectional and prospective analysis on cardiovascular mortality. Hypertension1989;13:392-400.
19.
Madhavan S. , Ooi WL, Cohen H., Alderman MHRelation of pulse pressure and blood pressure reduction to the incidence of myocardial infarction.Hypertension1994;23:395-401.
20.
Scuteri A., Cacciafesta M., Di Bernardo MG et al. Pulsatile versus steady-state component of blood pressure in elderly females: an independent risk factor for cardiovascular disease?J Hypertens1995;13:185-91.
21.
Witteman JC , Grobbee DE, Valkenburg HA et al. J-shaped relation between change in diastolic pressure and progression of aortic atherosclerosis . Lancet1994;343:504-7.
22.
Benetos A., Safar M., Rudnichi A. et al. Pulse pressure. A predictor of long-term cardiovascular mortality in a french male population.Hypertension1997 ;30:1410-5.
23.
Blacher J., Staessen JA, Girerd X. et al. Pulse pressure not mean pressure determines cardiovascular risk in older hypertensive patients. Arch Intern Med2000;160:1085-9.
24.
Benetos A., Zureik M., Morcet J. et al. A decrease in diastolic blood pressure combined with an increase in systolic blood pressure is associated with high cardiovascular mortality . J Am Coll Cardiol2000;35:673-80.
25.
Franklin SS , Larson MG, Khan SA et al. Does the relation of blood pressure to coronary heart disease risk change with ageing? The Framingham Heart Study . Circulation2001;103:1245-9.
26.
Alderman MH , Cohen H., Madhavan S.Distribution and determinants of cardiovascular events during 20 years of successful antihypertensive treatment . J Hypertens1998;16:761-9.
27.
Nichols WW, O'Rourke MFVascular impedance. McDonald's blood flow in arteries: theoretical, experimental and clinical principles. 4th edn, London,Arnold, 1998.
Franklin SS , GustinW 4th,Wong ND, Larson MG, Weber MA, Kannel WB, Levy D.Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart Study. Circulation1997;96:308-15.
30.
Franklin SS , Jacobs MJ, Wong ND, L'Italien GJ, Lapuerta P.Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III. Hypertension2001;37:869-74.
31.
Safar ME, London GMThe arterial system in human hypertension, In: Swales JD (Ed). Textbook of hypertension, Blackwell Scientific, London, 1994;85-102.
32.
Safar ME, Blacher J., Mourad JJ, London GMStiffness of carotid artery wall material and blood pressure in humans . Stroke2000;31:782-90.
33.
Küng CF , Lüscher TFDifferent mechanisms of endothelial dysfunction with aging and hypertension in rat aorta. Hypertension1995;25:194-200.
Blacher J., Pannier B., Guerin A., Marchais S., Safar M., London G.Impact of carotid stiffness on cardiovascular and all-cause mortality in end-stage renal failure. Hypertension1998 ;32:570-4.
36.
Blacher J., Asmar R., Djane S., London G., Safar M.Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients.Hypertension1999;33:1111-17.
37.
Meaume S., RudnichiA.,LynchA.,Bussy C., Sebban C., Benetos A., Safar MEAortic pulse wave velocity as a marker of cardiovascular disease in subjects over 70 years old. J Hypertens2001 ;19:871-7.
38.
Meaume S., BenetosA,Henry OF, Rudnichi A., Safar MEAortic pulse wave velocity predicts cardiovascular mortality in subjects >70 years of age. Arterioscler Thromb Vasc Biol2001;21:2046-50.
39.
Blacher J., Guerin A., Pannier B., Marchais S., Safar M., London G.Impact of aortic stiffness on survival in end-stage renal disease . Circulation1999;99:2434-9.
40.
Laurent S., Boutouyrie P., Asmar R. et al.Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension2001;37:1236-41.
41.
Boutouyrie P., Tropeano AI, Asmar R. et al. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study. Hypertension2002 ;39 : 1015.
42.
London G., Blacher J., Pannier B., Guerin A., Marchais S., Safar MEArterial wave reflections and survival in end-stage renal failure . Hypertension2001;38:434-8.
43.
Guerin A., Blacher J., Pannier B., Marchais S., Safar M., London G.Impact of aortic stiffness attenuation on survival of patients in end-stage renal disease. Circulation2001;103:987-92.
44.
Safar ME, London GM, for the Clinical Committee of Arterial Structure and Function.Therapeutic studies and arterial stiffness in hypertension: recommendations of the European Society of Hypertension. J Hypertens2000;18:1527-35.
45.
Safar MEAntihypertensive effects of nitrates in chronic human hypertension . J Appl Cardiol1990;5:69-81.
46.
Taylor MGWave travel in arteries and the design of the cardiovascular system . In: Pulsatile Blood Flow, Attinger EO (Ed). 1964, McGraw Hill: New York. p. 343-7.
47.
Kato H., Suzuki H., Tajima S., Ogata Y., Tominaga T., Sato A., SarutaT.Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells. J Hypertension1991;9:17-22.
48.
Albaladejo P., Bouaziz H., Duriez M., Gohlke P., Levy B., Safar M., Benetos A.Angiotensin converting enzyme inhibition prevents the increase in aortic collagen in rats. Hypertension1994;23:74-82.
49.
BenetosA,Levy BI, Lacolley P., Taillard F., Duriez M., Safar MERole of angiotensin II and bradykinin on aortic collagen following converting-enzyme inhibition in spontaneously hypertensive rats. Arterioscler Thromb Vasc Biol1997;17:3196-201.
50.
Lacolley P. , Safar ME, Lucet B., Ledudal K., Labat C., Benetos A.Prevention of aortic and cardiac fibrosis by spironolactone in old normotensive rats. J Am Coll Cardiol2001;37:662-7.
51.
Blacher J., Amah G., Girerd X. et al. Association between plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension. Am J Hypertens1997;10:1326-34.
Kass DA, Shapiro EP, Kawaguchi M. et al. Improved arterial compliance by a novel advanced glycation end-product crosslink breaker. Circulation2001;104:1464-70.
