Osteoblastoma is a rare benign primary bone tumor, which occurs in any part of the skeleton. Extraskeletal osteoblastoma is rather rare. We presented an extremely rare case of extraskeletal osteoblastoma located in the breast. The tumor recurred 7 months later after resection and transformed to aggressive osteoblastoma. The histopathological features, ultrasonic manifestations and ultrasonic differential diagnoses of the primary and recurrent tumors were discussed. The recommended treatment of the tumor is surgical excision. Due to its tendency of recurrence and potential malignant transformation, adequate resection and careful follow up is essential.
TrübenbachJ., NägeleT., BauerT. and ErnemannU., Preoperative embolization of cervical spine osteoblastomas: Report of three cases, Am J Neuroradiol27 (2006), 1910–1912.
2.
LlaugerJ., PalmerJ., AmoresS., BaguéS. and CaminsA., Primary tumors of the sacrum: Diagnostic imaging, Am J Roentgenol174 (2000), 417–424.
3.
MirraJ.M., GoldR. and MarcoveR.C., Bone tumours, Diagnosis and Treatment. Philadelphia: JB Lippincott, 1980, 108–122.
4.
GreenspanA., Benign bone-forming lesions: Osteoma, osteoid osteoma, and osteoblastoma. Clinical, imaging, pathologic, and differential considerations, Skeletal Radiol22 (1993), 485–500.
5.
KunzeE., EnderleA., RadigK. and Schneider-StockR., Aggressive osteoblastoma with focal malignant transformation and development of pulmonary metastases. A case report with a review of literature, Gen Diagn Pathol141 (1996), 377–392.
6.
AgarwalaR., GrahamR.J. and PanellaJ.S., CT and MRI of aggressive osteoblastoma of thyroid cartilage, J Comput Assist Tomogr20 (1996), 116–118.
7.
LedeboerQ.C., KerrebijnJ.D., GovaereF. and den BakkerM.A., Osteoblastoma of the larynx: A case report, Int J Surg Pathol13 (2005) 365–367.
8.
DeyrupA.T., MonsonD.K. and DorfmanH.D., Aggressive (epithelioid) osteoblastoma arising in soft tissue, Int J Surg Pathol16 (2008), 308–310.
9.
GhosalN., FurtadoS.V., GuptaK. and HegdeA.S., Fibro-osseous lesion of the pineal region resembling osteoblastoma: A case report, Neuropathology31 (2011), 158–161.
10.
NjimL., DhouibiA., TouilN., LahmarI., HadhriR., MoussaA. and ZakhamaA., Benign osteoblastoma in an unusual mastoid location, Eur Ann Otorhinolaryngol Head Neck127 (2010), 183–185.
11.
WoźniakA.W., NowaczykM.T., OsmolaK. and GolusinskiW., Malignant transformation of an osteoblastoma of the mandible: Case report and review of the literature, Eur Arch Otorhinolaryngol Jun267 (2010), 845–849.
12.
CervoniL., InnocenziG., RagusoM., SalvatiM. and CarusoR., Osteoblastoma of the calvaria: Report of two cases diagnosed with MRI and clinical review, Neurosurg Rev20 (1997), 51–54.
13.
Della RoccaC. and HuvosA.G., Osteoblastoma: Varied histological presentations with a benign clinical course. An analysis of 55 cases, Am J Surg Pathol20 (1996), 841–850.
14.
Figarella-BrangerD., Perez-CastilloM., GarbeL., GrisoliF., GambarelliD. and HassounJ., Malignant transformation of an osteoblastoma of the skull: An exceptional occurrence, J Neurosurg75 (1991), 138–142.
15.
OliveiraC.R., MendoncB.B., CamargoO.P., PintoE.M., NascimentoS.A., Latorre MdoR. and ZerbiniM.C., Classical osteoblastoma, atypical osteoblastoma, and osteosarcoma: A comparative study based on clinical, histological, and biological parameters, Clinics (Sao Paulo)62 (2007), 167–174.
