Terlipressin as rescue therapy for amine-resistant shock in premature infants: A report on two cases

Abstract

Terlipressin, a synthetic analogue of vasopressin, has been employed successfully against amine-resistant septic shock in both adults and children, including an 8-day-old infant. There have been no previous reports of its administration to premature infants. We report here on its compassionate use to treat two premature neonates with hypotensive shock that resisted volume replacement and amine therapy.