Abstract
The present review is dedicated to the problem of specificity of central nervous system (CNS) response to different destabilizing stimuli. It concerns some aspects of hypothalamic neuron involvement in central mechanisms of brain reactions to various stimulants. The effects of stress and antigenic stimulation on the hypothalamus are reviewed. Previously it was known that the brain responds specifically to various patterns of stimuli, which depends on the nature and intensity of the stimulus. Antigens have a special place amongst the stimuli applied to the brain. The effects of antigen depend on their biochemical nature though they also are considered to be stress factors.
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