The ISIS pulsed neutron and muon source at the Rutherford Appleton Laboratory in Oxfordshire is one of the world-leading centers for research in physical and life sciences. It is owned and operated by the Science and Technology Facilities Council. The popularity of neutron scattering experiments is rapidly growing due to the immense progress achieved in neutron scattering instrumentation and sample environment. Here we are going to review some trends in operation and development of sample environments used in neutron scattering and muon spectroscopy experiments at ISIS. We are also going to discuss ongoing sample environment related research and development projects.
I.F.Bailey, A review of sample environment in neutron scattering, Z. Kristallogr.218 (2003), 84.
3.
C.L.Bull, N.P.Funnell, M.G.Tucker, S.Hull, D.J.Francis and W.G.Marshall, PEARL: The high pressure neutron powder diffractometer at ISIS, High Pressure Research36(4) (2016), 493–511.
4.
B.E.Evans, R.B.E.Down, J.Keeping, O.Kirichek and Z.A.Bowden, Cryogen-free low temperature sample environment for neutron scattering based on pulse tube refrigeration, Meas. Sci. Technol.19 (2008), 034018. doi:10.1088/0957-0233/19/3/034018.
5.
B.J.Fuller, N.Lane and E.E.Benson, Life in the Frozen State, CRC Press, USA, 2004, p. 672.
6.
R.Haynes, A.M.Paradowska, M.A.H.Chowdhury, C.M.Goodway, R.Done, O.Kirichek and E.C.Oliver, An inert-gas furnace for neutron scattering measurements of internal stresses in engineering materials, Meas. Sci. Technol.23 (2012), 047002.
7.
M.K.Jacobsen, C.J.Ridley, A.Bocian, O.Kirichek, P.Manuel, D.Khalyavin, M.Azuma, J.P.Attfield and K.V.Kamenev, High-pressure cell for neutron diffraction with in situ pressure control at cryogenic temperatures, Rev. Sci. Instrum.85 (2014), 043904. doi:10.1063/1.4870061.
8.
M.G.Kibble, A.J.Ramirez-Cuesta, C.M.Goodway, B.E.Evans and O.Kirichek, Hydrogen gas sample environment for TOSCA, J. Phys.: Conf. Ser.554 (2014), 012006.
9.
O.Kirichek and P.Imperia, The 8th International Workshop on Sample Environment, Neutron News26 (2015), 2.
10.
O.Kirichek, A.K.Soper, B.Dzyuba, S.Callear and B.J.Fuller, Strong isotope effects on melting dynamics and ice crystallisation processes in cryo vitrification solutions, PLoS ONE10(3) (2015), e0120611.
11.
O.Kirichek, A.K.Soper, B.Dzyuba and W.V.Holt, Segregated water observed in a putative fish embryo cryopreservative, R. Soc. Open Sci.3 (2016), 150655. doi:10.1098/rsos.150655.
12.
O.Kirichek, J.D.Timms, J.F.Kelleher, R.B.E.Down, C.D.Offer, S.Kabra and S.Y.Zhang, Sample environment for neutron scattering measurements of internal stresses in engineering materials in the temperature range of 6 K to 300 K, Rev. Sci. Instrum.88 (2017), 025103. doi:10.1063/1.4974815.
13.
S.Klotz, Techniques in High Pressure Neutron Scattering, CRC Press, USA, 2012.
14.
M.P.M.Marques, A.L.M.Batista de Carvalho, V.Garcia Sakai, L.Hatterd and L.A.E.Batista de Carvalho, Intracellular water – an overlooked drug target? Cisplatin impact in cancer cells probed by neutrons, Phys. Chem. Chem. Phys.19 (2017), 2702. doi:10.1039/C6CP05198G.
15.
I.Massie, C.Selden, H.Hodgson, B.J.Fuller, S.Gibbons and G.J.Morris, Cryopreservation of large volumes of cells for regenerative medicine: Active control of the freezing process, Tissue Engineering: Part C20 (2014), 693. doi:10.1089/ten.tec.2013.0571.
16.
K.Murata and H.Tanaka, General nature of liquid-liquid transition in aqueous organic solutions, Nature Communications4 (2013), 2844.
17.
E.C.Oliver, B.E.Evans, M.A.H.Chowdhury, R.A.Major, O.Kirichek and Z.A.Bowden, Novel testing chamber for neutron scattering measurements of internal stresses in engineering materials at cryogenic temperatures, Meas. Sci. Technol.19 (2008), 034019. doi:10.1088/0957-0233/19/3/034019.
18.
C.J.Ridley, P.Manuel, D.Khalyavin, O.Kirichek and K.V.Kamenev, A novel compact three-dimensional laser-sintered collimator for neutron scattering, Rev. Sci. Instrum.86 (2015), 095114. doi:10.1063/1.4931695.
19.
J.R.Santisteban, M.R.Daymond, J.A.James and L.Edwards, ENGIN-X: A third-generation neutron strain scanner, J. Appl. Cryst.39 (2006), 812. doi:10.1107/S0021889806042245.
20.
Y.Tsuchiya, H.Suzuki, T.Umeno, S.Machiya and K.Osamura, Development of a cryogenic load frame for a neutron diffractometer, Meas. Sci. Technol.21 (2010), 025904. doi:10.1088/0957-0233/21/2/025904.
