In this research work, a new multilayer fuzzy inference system is proposed for diagnosis of renal cancer. This proposed automated diagnosis of renal cancer using multilayer Mamdani fuzzy inference system can help to classify the different stages of renal cancer such as no cancer, stage 1, stage 2, stage 3 or stage 4 cancer. This expert system has four input variables at layer 1 and similarly seven input variables at layer 2. At layer 1, the input variables are smoking, dialysis, occupational exposure and genetic or hereditary that recognize the output conditions of renal or kidney to be normal or to have renal cancer. The further input variables for layer 2 are haematuria (blood in urine), red blood cell count, flank pain, tumor size, Von Hippel-Lindau gene, high blood pressure and trichloroethylene exposure that reveal the output condition of kidney such as stage 1 cancer, stage 2 cancer, stage 3 cancer or stage 4 cancer. The novelty in this research work is development of multilayer fuzzy inference system that deals with fuzzy values, uncertain and ambiguous data to detect the stage of renal cancer by using two layers. This paper presents an analysis of results accurately using the proposed expert system to model the renal cancer process with medical expert advice. The confidence indicator for this proposed expert system is 95%.
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