This paper investigates the global dynamics of Chikungunya virus (CHIKV) infection model with antibody immune response. We incorporate two ways of transmissions CHIKV-to-cell and cell-to-cell. We incorporate three types of discrete time delays into the model. The first time delay is the time between CHIKV entry an uninfected monocyte to become latent infected. The second time delay is the time between CHIKV entry on uninfected monocyte and the production of immature CHIKV. The third time delay represents the CHIKV’s maturation time. Nonnegativity and boundedness properties of the solutions are proven. Further, global stability of the equilibria is established by constructing Lyapunov functions and by applying applying LaSalle’s invariance principle.
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