Various acute phase reactants are produced in response to inflammatory stimuli, one of them is C-reactive protein. Serum levels of C-Reactive protein are useful to monitor and diagnose inflammatory process associated with disease as it being one of the valuable biomarkers in various clinical conditions, increase in level of C-Reactive protein is found in subjects with periodontal disease, which in turn can act as useful biomarker to diagnose cardiovascular disease, adverse pregnancy outcome as they being associated with periodontal disease. This manuscript is brief overview of C-Reactive protein and its relation with periodontal disease and systemic health.
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