Prosthetic implants, such as knee or hip prostheses, have significantly improved the wellbeing of citizens with articulation problems. However, there are still significant challenges in these procedures, being recurring infections one of the most challenging. In this context, hyperthermia has been studied as an effective alternative to antibiotics for biofilm eradication. Among the different heating alternatives, induction heating arises as the idoneous for this application due to its contactless nature and the metallic alloys used in prosthesis. This paper details the design of a portable induction heating system for implanted prosthesis disinfection.
GbejuadeH.O.LoveringA.M. and WebbJ.C., The role of microbial biofilms in prosthetic joint infections, Acta Orthop86(2) (2015), 147–158, doi:10.3109/17453674.2014.966290, (in eng).
2.
PijlsB.G.SandersI.M.J.G.KuijperE.J. and NelissenR.G.H.H., Synergy between induction heating, antibiotics, and N-acetylcysteine eradicates Staphylococcus aureus from biofilm, International Journal of Hyperthermia37(1) (2020), 130–136, doi:10.1080/02656736.2019.1710269.
3.
StaufferP.R.SneedP.K.HashemiH. and PhillipsT.L., Practical induction heating coil designs for clinical hyperthermia with ferromagnetic implants, IEEE Transactions on Biomedical Engineering41(1) (1994), 17–28, doi:10.1109/10.277267.
4.
KwizeraE.A.StewartS.MahmudM.M. and HeX., Magnetic nanoparticle-mediated heating for biomedical applications, J Heat Transfer144(3) (2022), doi:10.1115/1.4053007, (in eng).
5.
KamedaT.OhkumaK.SanoN.BatbayarN.TerashimaY. and TeradaK., Development of a compact induction-heated autoclave with a dramatically shortened sterilization cycle in orthodontic clinics, Orthodontic Waves73(2) (2014), 55–60, doi:10.1016/j.odw.2014.03.001.
6.
WangQ.VachonJ.PrasadB.PybusC.A.LapinN.ChopraR., Alternating magnetic fields and antibiotics eradicate biofilm on metal in a synergistic fashion, NPJ Biofilms and Microbiomes7(1) (2021), 68, doi:10.1038/s41522-021-00239-y.
7.
PijlsB.G.SandersI.KujiperE.J. and NelissenR., Induction heating for eradicating Staphylococcus epidermidis from biofilm, Bone Joint Res9(4) (2020), 192–199, doi:10.1302/2046-3758.94.Bjr-2019-0274.R1, (in eng).
8.
GreenbergD.TepperJ. and ChopraR., System for application of alternating magnetic fields to reduce infection, Patent Appl. (2022)), [Online]. Available: EP22382889.8 PCT/EP2023/076644.
9.
LucíaO.MaussionP.DedeE. and BurdíoJ.M., Induction heating technology and its applications: Past developments, current technology, and future challenges, IEEE Transactions on Industrial Electronics61(5) (2014), 2509–2520, doi:10.1109/TIE.2013.2281162, (in English).
10.
SarnagoH.LucíaO.MedianoA. and BurdíoJ.M., Analysis and design of high-efficiency resonant inverters for domestic induction heating applications, International Journal of Applied Electromagnetics and Mechanics44(2) (2014), 201–208, doi:10.3233/JAE-141760, (in English).
11.
LucíaÓ.SarnagoH.AceroJ. and BurdíoJ.M., Induction heating appliances: Toward more sustainable and smart home appliances, in: Energy Smart Appliances: Applications, Methodologies, and ChallengesMoreno-MuñozA. and GiacominiN. (eds), Wiley-IEEE Press, USA, 2023.
12.
LucíaO.DomínguezA.SarnagoH. and BurdíoJ.M., Induction Heating, in: Control of Power Electronic Converters and SystemsBlaabjergF. (ed.), 1 edn, Vol. 2, Elsevier, USA, 2018, ch. 21.
13.
Gomez-PoloC.LarumbeS.Perez-LandazabalJ.I. and PastorJ.M., Analysis of heating effects (magnetic hyperthermia) in FeCrSiBCuNb amorphous and nanocrystalline wires, Journal of Applied Physics111(7) (2012), 07A314-07A314-3, doi:10.1063/1.3672850.
14.
SarnagoH.LuciaO. and BurdíoJ.M., High frequency and power density gallium nitride based inverter for magneto fluid hyperthermia, in: IEEE Annual Conference of the Industrial Electronics Society, 2016, pp. 5222–5225. doi:10.1109/IECON.2016.7794026.
15.
SarnagoH.LucíaO.MedianoA. and BurdíoJ.M., Analytical model of the half-bridge series resonant inverter for improved power conversion efficiency and performance, IEEE Transactions on Power Electronics30(8) (2015), 4128–4143, doi:10.1109/TPEL.2014.2359576.
16.
LucíaO.BurdíoJ.M.MillánI.AceroJ. and PuyalD., Load-adaptive control algorithm of half-bridge series resonant inverter for domestic induction heating, IEEE Transactions on Industrial Electronics56(8) (2009), 3106–3116, doi:10.1109/TIE.2009.2022516, (in English).
17.
GuillénP.SarnagoH.LucíaÓ. and BurdíoJ.M., Acoustic noise analysis of multiplexed strategies in multi-output converters for induction cooktops, International Journal of Applied Electromagnetics and Mechanics63(s1) (2020), 59–68, doi:10.3233/JAE-209115.
18.
MichalskiK.A. and NevelsR.D., On the use of the Coulomb gauge in solving source-excited boundary value problems of electromagnetics, IEEE Transactions on Microwave Theory and Techniques36(9) (1988), 1328–1333, doi:10.1109/22.3679.
19.
CorderoE.GómezE.MedelM. and EstebanJ., Desinfección in vitro de componentes metálicos colonizados por biofilms maduros de microorganismos habituales en infección protésica, presented at the Sociedad Española de Cirugía Ortopédica y Traumatología, 2022.
