Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study

[Journal of Alzheimer’s Disease, 67(1) (2019), 197–210, DOI 10.3233/JAD-180479] https://content.iospress.com/articles/journal-of-alzheimers-disease/jad180479

On page 202 there was a numerical error in Table 1. The number of participants with FTD at two-year follow-up was shown as “8”, whereas the correct number was “28”. The correct Table 1 is placed below, with the corrected number in bold text.

Table 1

Descriptive data at baseline, one- and two-year follow-up. Means (standard deviations) are given for all continuous variables. p-Values were calculated by estimating the linear mixed model and reported for change from baseline to one-year and from baseline to two-year follow-up (latter not denoted if identical) for YOD combined

Assessment	Baseline				One year				Two years				P-values
	N	AD	N	FTD	N	AD	N	FTD	N	AD	N	FTD
Participants, n		50		38		44		25		41		28
Age	50	63.3 (4.0)	38	62.7 (5.8)	44	–	25	–	41	–	28	–
Male, n (%)		25 (50)		23 (61)		21 (48)		14 (56)		18 (44)		15 (54)
Education	45	13.3 (3.0)	34	12.8 (3.7)		–		–		–		–
MMSE	45	20.6 (5.4)	36	22.9 (7.5)	32	18.6 (5.5)	18	23.1 (6.4)	29	15.5 (7.1)	15	22.5 (7.9)	0.003/<.001
CDR	50	4.9 (3.5)	38	4.9 (3.4)	42	6.7 (4.7)	21	7.5 (5.0)	39	9.2 (5.2)	21	7.8 (5.4)	<0.001
Awareness, n (%)	48		37		37		16		32		20		0.035/<0.001
Intact		36 (75)		15 (40)		21 (57)		6 (38)		12 (38)		7 (35)
Impaired		12 (25)		22 (60)		16 (43)		10 (62)		20 (62)		13 (65)
CSDD	50	6.4 (5.1)	33	7.9 (6.2)	43	7.7 (6.3)	21	8.2 (5.4)	38	7.0 (5.2)	20	8.9 (4.6)	0.163/0.461
NPI-Q	50	5.4 (5.6)	32	9.3 (6.8)	43	6.0 (5.4)	20	7.8 (5.4)	38	7.1 (5.8)	28	9.5 (6.3)	0.884/0.250
ADL	48	21.3 (8.5)	32	21.3 (6.6)	42	25.8 (9.5)	16	27.3 (12.3)	39	26.2 (9.1)	23	24.0 (10.6)	0.001/0.005
Medication	49	2.7 (2.3)	37	3.0 (2.4)	37	2.9 (2.3)	15	3.0 (2.5)	40	3.1 (1.9)	23	3.4 (3.1)	0.728/0.244
Met needsa	47	4.0 (2.4)	32	4.2 (2.5)	37	3.1 (1.9)	12	4.7 (2.7)	22	4.5 (2.5)	8	2.9 (1.2)	0.087/0.828
Unmet needsa	47	0.2 (0.6)	32	0.6 (1.3)	37	0.2 (0.6)	12	0.4 (0.9)	22	0.5 (1.5)	8	1.5 (2.1)	0.752/0.112
QOL–AD	50	37.4 (6.0)	38	34.8 (7.1)	41	36.7 (5.2)	20	33.7 (4.8)	37	35.4 (6.3)	27	32.9 (6.6)	0.137/0.003

AD, Alzheimer’s disease; FTD, frontotemporal dementia; MMSE, Mini Mental State Examination; CDR, Clinical Dementia Rating scale; CSDD, Cornell Scale for Depression in Dementia; NPI, Neuropsychiatric Inventory Questionnaire; ADL, The Physical Self-Maintenance Scale and Lawton Activities of Daily Living scale total score; QOL–AD, Quality of Life – Alzheimer’s Disease scale. aSelf-reported needs assessed for participants living at home.