This study surveys the development of Alzheimer’s disease (AD) in the research literature, the scientific community, and the journals containing AD papers over a 35-year period. Research papers on AD published from 1983 to 2017 in journals indexed in the Web of Science were analyzed in seven five-year periods. The number of AD papers increased from 1,095 in 1983–1987 to 50,532 by 2013–2017 and in the same time period, the number of participating countries went from 27 to 152. The US was the most prolific country throughout, followed by several European countries, Canada, Australia, and Japan. Asian countries have emerged and by 2013–2017, China surpassed all but the US in productivity. Countries in Latin America and Africa have also contributed to AD research. Additionally, several new non-governmental institutions (e.g., ADNI, ADI) have emerged and now play a key role in the fight against AD. Likewise the AD scientific publishing universe evolved in various aspects: an increase in number of journals containing AD papers (227 journals in 1983–1987 to 3,257 in 2013–2017); appearance of several AD-focused journals, e.g., Alzheimer’s & Dementia, Journal of Alzheimer’s Disease; and the development of special issues dedicated to AD. Our paper complements the numerous extant papers on theoretical and clinical aspects of AD and provides a description of the research landscape of the countries and journals contributing papers related to AD.
Alzheimer’s Association (2018) 2018 Alzheimer’s disease facts and figures. Alzheimers Dement14, 367–429.
2.
PistollatoF, OhayonEL, LamA, LangleyGR, NovakTJ, PamiesD, PerryG, TrushinaE, WilliamsRS, RoherAE, HartungT, HarnadS, BarnardN, MorrisMC, LaiMC, MerkleyR, ChandrasekeraPC (2016) Alzheimer disease research in the 21st century: Past and current failures, new perspectives and funding priorities. Oncotarget7, 38999–39016.
3.
JuckerM, BeyreutherK, HaassC, NitschRM, ChristenY (2006) Alzheimer: 100 years and beyond. Springer-Verlag, Berlin Heidelberg.
SorensenAA (2009) Alzheimer’s disease research: Scientific productivity and impact of the top 100 investigators in the field. J Alzheimers Dis16, 451–465.
8.
SorensenAA, SearyA, RiopelleK (2010) Alzheimer’s disease research: A COIN study using co-authorship network analytics. Procedia Soc Behav Sci2, 6582–6586.
9.
ChenH, WanY, JiangS, ChengY (2014) Alzheimer’s disease research in the future: Bibliometric analysis of cholinesterase inhibitors from 1993 to 2012. Scientometrics98, 1865–1877.
10.
SongM, Eun HeoG, LeeD (2015) Identifying the landscape of Alzheimer’s disease research with network and content analysis. Scientometrics102, 905–927.
11.
LeeD, KimWC, CharidimouA, SongM (2015) A bird’s-eye view of Alzheimer’s disease research: Reflecting different perspectives of indexers, authors, or citers in mapping the field. J Alzheimers Dis45, 1207–1222.
12.
Serrano-PozoA, AldridgeGM, ZhangQ (2017) Four decades of research in Alzheimer’s Disease (1975-2014): A bibliometric and scientometric analysis. J Alzheimers Dis59, 763–783.
13.
DongR, WangH, YeJ, WangM, BiY (2019) Publication trends for Alzheimer’s disease worldwide and in China: A 30-year bibliometric analysis. Front Hum Neurosci13, 259.
14.
AksnesDW, LangfeldtL, WoutersP (2019) Citations, citation indicators, and research quality: An overview of concepts and theories. SAGE Open9, https://doi.org/10.1177/2158244019829575.
15.
GarfieldE (1965) Can citation indexing be automated? In Statistical Association Methods for Mechanized Documentation: Symposium Proceedings, Stevens ME, Guiliano VE, Heilprin LB, eds. National Bureau of Standards, Washington, DC, pp. 189–192.
16.
TerryRD (1963) The fine structure of neurofibrillary tangles in Alzheimer’s disease. J Neuropathol Exp Neurol22, 629–642.
17.
KiddM (1964) Alzheimer’s disease –An electron microscopical study. Brain87, 307–320.
18.
KatzmanR (1976) Editorial: The prevalence and malignancy of Alzheimer disease. A major killer. Arch Neurol33, 217–218.
19.
HuguesME, PeelerJ, HogeneshJB, TrojanoswkiJQ (2014) The growth and impact of Alzheimer disease centers as measured by social network analysis. JAMA Neurol71, 412–420.
20.
KhachaturianZS, KhachaturianA (2015) Politics of science: Progress toward prevention of the dementia–Alzheimer’s syndrome. Mol Aspects Med43-44, 3–15.
21.
Anonymous (2012) Alzheimer’s Association Update. Alzheimers Dement7, 250–252.
22.
Alzheimer’s Association, Alzheimer’s Association National Plan Care and Support Milestone Workgroup, BorsonS, BoustaniMA, BuckwalterKC, BurgioLD, ChodoshJ, FortinskyRH, GiffordDR, GwytherLP, KorenMJ, LynnJ, PhillipsC, RohertyM, RonchJ, StahlC, RodgersL, KimH, BaumgartM, GeigerA (2016) Report on milestones for care and support under the U.S. National Plan to Address Alzheimer’s Disease. Alzheimers Dement12, 334–369.
23.
ThiesW (2011) Stopping a thief and killer: Alzheimer’s disease crisis demands greater commitment to research. Alzheimers Dement7, 175–176.
AltimusCM, KellerK, BrannellyP, RossE, LinC-T, RileyEAU, BriggsL, SmithJ, StevensM (2019) Analysis of tauopathy research funding between 2006 and 2016 reveals critical gaps in research priorities. Alzheimers Dement15, 42–54.
CummingsJL, TongG, BallardC (2019) Treatment combinations for Alzheimer’s disease: Current and future pharmacotherapy options. J Alzheimers Dis67, 779–794.
31.
GuptaBM, BalaA (2013) Alzheimer’s disease research in India: A scientometric analysis of publications output during 2002-2011. Res Neurol2013, 204542.
32.
RobertC, WilsonCS, LiptonRB, ArretoCD (2019) Parkinson’s disease: Evolution of the scientific literature from 1983 to 2017 by countries and journals. Parkinsonism Relat Disord61, 10–18.
33.
GlennerGG, WongCW (1984) Alzheimer’s disease and Down’s syndrome: Sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun122, 1131–1135.
34.
Grundke-IqbalI, IqbalK, QuinlanM, TungYC, ZaidiMS, WisniewskiHM (1986) Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. Proc Natl Acad Sci U S A261, 6084–6089.
35.
BrionJP, Flament-DurandJ, DustinP (1986) Alzheimer’s disease and tau proteins. Lancet328, 1098.
AsuniAA, BoutajangoutA, QuartermainD, SigurdssonEM (2007) Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements. J Neurosci27, 9115–9129.
38.
JackCRJr, KnopmanDS, JagustWJ, ShawLM, AisenPS, WeinerMW, PetersenRC, TrojanowskiJQ (2010) Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade. Lancet Neurol9, 119–128.
39.
McKhannGM, KnopmanDS, ChertkowH, HymanBT, JackCRJr, KawasCH, KlunkWE, KoroshetzWJ, ManlyJ, MayeuxR, MohsRC, MorrisJC, RossorMN, ScheltensP, CarrilloMC, ThiesB, WeintraubS, PhelpsCH (2011) The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement7, 263–269.
40.
DuboisB, HampelH, FeldmanHH, ScheltensP, AisenP, AndrieuS, BakardjianH, BenaliH, BlennowK, BroichK, CavedoE, CrutchS, DartiguesJF, DuyckaertsC, EpelbaumS, FrisoniGB, GauthierS, GenthonR, GouwAA, HabertMO, HoltzmanDM, KivipeltoM, ListaS, MolinuevoJL, O’BryantSE, RabinoviciGD, RoweC, SallowayS, SchneiderLS, SperlingR, TeichmannM, CarrilloMC, CummingsJ, JackCRJr, from the Proceedings of the Meeting of the International Working Group (IWG) and the American Alzheimer’s Association on “The Preclinical State of AD”; July 23, 2015; Washington DC, USA (2016) Preclinical Alzheimer’s disease: Definition, natural history, and diagnostic criteria. Alzheimers Dement12, 292–323.
41.
JackCRJr, BennettDA, BlennowK, CarrilloMC, DunnB, HaeberleinSB, HoltzmanDM, JagustW, JessenF, KarlawishJ, LiuE, MolinuevoJL, MontineT, PhelpsC, RankinKP, RoweCC, ScheltensP, SiemersE, SnyderHM, SperlingR (2018) Contributors, NIA-AA Research Framework: Towards a biological definition of Alzheimer’s disease. Alzheimers Dement14, 535–562.
ZhouX, ChenY, MokKY, ZaoQ, ChenK, ChenY, HardyJ, LiY, FuAKY, GuoQ, YpNY, and for the Alzheimer’s Disease Neuroimaging Initiative (2018) Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis. Proc Natl Acad Sci U S A115, 1697–1708.
51.
ShaoJ, ShenH (2011) The outflow of academic papers from China: Why is it happening and can it be stemmed?. Learn Publ24, 95–97.
52.
LiY (2016) “Publish SCI papers or no degree”: Practices of Chinese doctoral supervisors in response to the publication pressure on science students. Asian Pacific J Educ36, 545–558.
53.
QuanW, ChenB, ShuF (2017) Publish or impoverish: An investigation of the monetary reward system of science in China (1999-2016). Aslib J Inform Manag69, 1–18.
54.
XuG, ZhangZ, LvQ, LiY, YeR, XiongY, JiangY, LiuX (2014) NSFC health research funding and burden of disease in China. PLoS One9, e111458.
55.
PooMM, DuJL, YpNY, XiongZQ, XuB, TanT (2016) China Brain Project: Neuroscience, brain diseases, and brain-inspired computing. Neuron92, 591–596.
56.
XiaJ, WrigthJ, AdamsCE (2008) Five large Chinese biomedical bibliographic databases: Accessibility and coverage. Health Inf Lib J25, 55–61.
57.
CohenJF, KorevaarDA, WangJF, SpijkerR, BossuytPM (2015) Should we search Chinese biomedical databases when performing systematic reviews?. Syst Rev4, 23.
58.
LeydesdorffL, WagnerCS, BornmannL (2014) The European Union, China, and the United States in the top-1% and top-10% layers of most-frequently cited publications: Competition and collaborations. J Informetrics8, 606–617.
59.
WuYT, AliGC, GuerchetM, PrinaAM, ChanKY, PrinceM, BrayneC (2018) Prevalence of dementia in mainland China, Hong Kong and Taiwan: An updated systematic review and meta-analysis. Int J Epidemiol47, 709–719.
60.
FengL, LiJ, YuJT, ZhangC, YangB, VellasB, LiC (2018) Prevention of Alzheimer’s disease in Chinese populations: Status, challenges, and directions. J Prev Alzheimers Dis5, 90–94.
61.
Abi-RachedJM (2012) From brain to neuro: The Brain Research Association and the making of British neuroscience, 1965-1996. J Hist Neurosci21, 189–213.
62.
WilsonD (2017) Calculable people? Standardising assessment guidelines for Alzheimer’s disease in 1980s Britain. Med Hist61, 500–524.
FrancisPT, CostelloH, HayesGM (2018) Brains for dementia research: Evolution in a longitudinal brain donation cohort to maximize current and future value. J Alzheimers Dis66, 1635–1644.
ElliottC, RojoAI, RibeE, BroadstockM, XiaW, MorinP, SemenovM, BaillieG, CuadradoA, Al-ShawiR, BallardCG, SimonsP, KillickR (2018) A role for APP in Wnt signalling links synapse loss with β-amyloid production. Transl Psychiatr8, 179.
68.
GoedertM, GhettiB (2007) Alois Alzheimer: His life and times. Brain Pathol17, 57–62.
JessenF, SpottkeA, BoeckerH, BrosseronF, BuergerK, CatakC, FliessbachK, FrankeC, FuentesM, HenekaMT, JanowitzD, KilimannI, LaskeC, MenneF, NestorP, PetersO, PrillerJ, ProssV, RamirezA, SchneiderA, SpeckO, SpruthEJ, TeipelS, VukovichR, WesterteicherC, WiltfangJ, WolfsgruberS, WagnerM, DüzelE (2018) Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE). Alzheimers Res Ther10, 15.
74.
BonavitaV (2011) The Italian neurological schools of the twentieth century. Funct Neurol26, 77–85.
75.
FedericoA (2011) Italian neurology: Past, present, and future. Funct Neurol26, 73–76.
76.
AgostiniM, FasolatoC (2016) When, where and how? Focus on neuronal calcium dysfunctions in Alzheimer’s disease. Cell Calcium60, 289–298.
77.
RicciarelliR, E. FedeleE (2017) The amyloid cascade hypothesis in Alzheimer’s disease: It’s time to change our mind. Curr Neuropharmacol15, 926–935.
78.
MecocciP, BoccardiV, CecchettiR, BastianiP, ScamosciM, RuggieroC, BaroniM (2018) A long journey into aging, brain aging and Alzheimer’s disease following the oxidative stress tracks. J Alzheimers Dis62, 1319–1335.
79.
FrisoniGB (2010) Alzheimer’s Disease Neuroimaging Initiative in Europe. Alzheimers Dement6, 280–285.
The Research Project on the Construction and Use of a Model for an International Public-Private Partnership (PPP) in Dementia Research. http://japanhpn.org/en/dementia2-1-2/, accessed on June 2019.
88.
TakahashiK, YamanakaS (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell126, 663–676.
TongG, IzquierdoP, RaashidRA (2017) Human induced pluripotent stem cells and the modelling of Alzheimer’s disease: The human brain outside the dish. Open Neurol J11, 27–38.
91.
KametaniF, HasegawaM (2018) Reconsideration of amyloid hypothesis and tau hypothesis in Alzheimer’s disease. Front Neurosci12, 25.
SadoM, NinomiyaA, ShikimotoR, IkedaB, BabaT, YoshimuraK, MimuraM (2018) The estimated cost of dementia in Japan, the most aged society in the world. PLoS One13, e0206508.
95.
OkanoH, MiyawakiA, KasaiK (2015) Brain/MINDS: Brain-mapping project in Japan. Phil Trans R Soc B370, 20140310.
FischerKE, AustadSN (2011) The development of small primate models for aging research. ILAR J52, 78–88.
98.
de StrooperB, SaftigP, CraessaertsK, VandersticheleV, GuhdeG, AnnaertW, Von FiguraK, Van LeuvenF (1998) Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature391, 387–390.
Haeffner-CavaillonN, DevosP, LedouxS, MénardJ (2015) The Third French Alzheimer Plan: Analysis of the influence of a national public health initiative on scientific research productivity and impact. Alzheimers Res Ther7, 60.
103.
MastersCL, SimmsG, WeinmanNA, MulthaupG, Mc DonaldBL, K. BeyreutherK (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci U S A82, 4245–4249.
104.
St George-HyslopPH, TanziRE, PolinskyRJ, HainesJL, NeeL, WatkinsPC, MyersRH, FeldmanRG, PollenD, DrachmanD, et al. (1987) The genetic defect causing familial Alzheimer’s disease maps on chromosome 21. Science235, 885–890.
105.
TanziRE, GusellaJF, WatkinsPC, BrunsGA, St George-HyslopP, Van KeurenML, PattersonD, PaganS, KurnitDM, NeveRL (1987) Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science235, 880–884.
106.
GrahamJE, RockwoodK, BeattieBL, EastwoodR, GauthierS, TuokkoH, McDowellI (1997) Prevalence and severity of cognitive impairment with and without dementia in an elderly population. Lancet349, 1793–1796.
107.
SherifT, RiouxP, RousseauME, KassisN, BeckN, AdalatR, DasS, GlatardT, EvansAC (2014) CBRAIN: A web-based, distributed computing platform for collaborative neuroimaging research. Front Neuroinform8, 54.
ParkHK, NaDL, HanSH, KimJY, CheongHK, KimSY, KimSY, HongCH, KimDK, KuBD, MoonSY, LeeJY, ShimYS, YounYC, KimEJ, KimBC, ParkKH, ChaKR, SeoSW, LeeJH (2011) Clinical characteristics of a nationwide hospital-based registry of mild-to-moderate Alzheimer’s disease patients in Korea: A CREDOS (Clinical Research Center for Dementia of South Korea) study. J Korean Med Sci26, 1219–1226.
110.
NakanishiM, NakashimaT (2014) Features of the Japanese national dementia strategy in comparison with international dementia policies: How should a national dementia policy interact with public health- and social-care systems?. Alzheimers Dement10, 468–476.
111.
ByunMS, YiD, LeeJH, ChoeYM, SohnBK, LeeJY, ChoiHJ, BaekH, KimYK, LeeYS, SohnCH, Mook-JungI, ChoiM, LeeYJ, LeeDW, RyuSH, KimSG, KimJW, WooJI, LeeDY, KBASE Research Group (2017) Korean Brain Aging Study for the early diagnosis and prediction of Alzheimer’s disease: Methodology and baseline sample characteristics. Psychiatry Investig14, 851–863.
112.
WinbladB, AmouyelP, AndrieuS, BallardC, BrayneC, BrodatyH, Cedazo-MinguezA, DuboisB, EdvardssonD, FeldmanH, FratiglioniL, FrisoniGB, GauthierS, GeorgesJ, GraffC, IqbalK, JessenF, JohanssonG, JönssonL, KivipeltoM, KnappM, MangialascheF, MelisR, NordbergA, RikkertMO, QiuC, SakmarTP, ScheltensP, SchneiderLS, SperlingR, TjernbergLO, WaldemarG, WimoA, ZetterbergH (2016) Defeating Alzheimer’s disease and other dementias: A priority for European science and society. Lancet Neurol15, 455–532.
113.
VaudanoE, VannieuwenhuyseB, Van Der GeytenS, van der LeiJ, VisserPJ, StrefferJ, RitchieC, McHaleD, LovestoneS, Hofmann-ApitiusM, TruyenL, GoldmanM (2015) Boosting translational research on Alzheimer’s disease in Europe: The Innovative Medicine Initiative AD research platform. Alzheimers Dement11, 1121–1122.
ManesF (2016) The huge burden of dementia in Latin America. Lancet Neurol15, 29.
116.
SnyderHM, Cardenas-AguayoMdC, AlonsoA, BainL, IqbalK, CarrilloMC (2016) Alzheimer’s disease research in Ibero America. Alzheimers Dement12, 749–754.
117.
ParraMA, BaezS, AllegriR, NitriniR, LoperaF, SlachevskyA, CustodioN, LiraD, PiguetO, KumforF, HuepeD, CogramP, BakT, ManesF, IbanezA (2018) Dementia in Latin America. Assessing the present and envisioning the future. Neurology90, 222–231.
118.
BaezS, IbanezA (2016) Dementia in Latin America: An emergent silent tsunami. Front Aging Neurosci8, 253.
119.
AllegriRF (2008) The pioneers of clinical neurology in South America. J Neurol Sci271, 29–33.
120.
de ToledoAASF, NitriniR, de Campos BottinoCM, CaramelliP (2014) Brazilian research on cognitive impairment and dementia from 1999 to 2013. Dement Neuropsychol8, 394–398.
121.
Van NoordenR (2014) The impact gap: South America by the numbers. Nature510, 202–203.
Gutierrez-RobledoLM, ArrietaIC (2015) Dementia in Mexico: The need for a National Alzheimer’s Plan. Gac Med Mex151, 620–625.
124.
GBD2016 (2019) Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol18, 88–106.
125.
FuentesP, AlbalaC (2014) An update on aging and dementia in Chile. Dem Neuropsychol8, 317–322.
126.
HojmanDA, DuarteF, Ruize-TagleJ, BudnichM, DelgadoC, SchlachevskyA (2017) The cost of dementia in an unequal country: The case of Chile. PLoS One12, e0172204.
127.
RussoMJ, GustafsonD, VasquezS, SuraceE, GuinjoanS, AllegriRF, SevleverG, members of the Argentina-Alzheimer’s Disease Neuroimaging Initiative (2014) Creation of the Argentina-Alzheimer’s Disease Neuroimaging Initiative. Alzheimers Dement10, S84–S87.
Sepulveda-FallaD, VillegasA, LoperaF, GlatzelM (2019) The Colombian-German network for neurodegenerative research: UndoAD. Lancet Neurol18, 29.
130.
FullerJT, Cronin-GolombA, GatchelJR, MD, NortonDJ, Guzmán-VélezE, JacobsHIL, HansseuwB, Pardilla-DelgadoE, ArtolaA, BaenaA, BocanegraY, KosikKS, ChenK, TariotPN, JohnsonK, SperlingRA, ReimanEM, LoperaF, QuirozYT (2019) Biological and cognitive markers of presenilin1 E280A autosomal dominant Alzheimer’s disease: A comprehensive review of the Colombian kindred. J Prev Alzheimers Dis6, 112–120.
131.
WPA2015 (2015)World Population Ageing 2015. United Nations, New York.
132.
PoreauB (2016) Progressive and self-limiting neurodegenerative disorders in Africa: A new prominent field of research led by South Africa but without strong health policy. Pan Afr Med J23, 220.
133.
RobertC, WilsonCS, LiptonRB, ArretoCD (2017) Growth of headache research: A 1983-2014 bibliometric study. Cephalalgia37, 1299–1309.
134.
Aleixander-BenaventR, Alonso-ArroyoA, Gonzales de DiosJ, Vidal-InferA, Gonzales-MunosM, SampereAP (2015) Bibliometric profile of the global scientific research on multiple sclerosis (2003-2012). Mult Sclerosis J21, 235–245.
135.
BongaartsJ (2009) Human population growth and the demographic transition. Phil Trans R Soc B364, 2985–2990.
136.
WPA2017 (2017) World Population Ageing 2017. United Nations, New York.
137.
GuerchetM, MaystonR, Lloyd-SherlockP, PrinceM, AboderinI, AkinyemiR, PaddickSM, WimoA, Amoakoh-ColemanM, UwakweR, EzeahP (2017) Alzheimer’s Disease International, Dementia in Sub-Saharan Africa. Challenges and Opportunities. https://www.alz.co.uk/research/dementia-sub-saharan-africa.pdf, accessed on July 2019.
FrisoniGB, HennemanWJP, WeinerMW, ScheltensP, VellasB, ReynishE, HudecovaJ, HampelH, BurgerK, BlennowK, WaldemarG, JohannsenP, WahlundLO, ZitoG, RossiniPM, WinbladB, BarkhofF, and Alzheimer’s Disease Neuroimaging Initiative (2008) The pilot European Alzheimer’s Disease Neuroimaging Initiative (E-ADNI) of the European Alzheimer’s Disease Consortium. Alzheimers Dement4, 255–264.
141.
EliasA, CumminsTL, HoopwoodM, RosenfeldJV, DoreV, LambF, WilliamsR, VillemagneVLL, RoweCC (2017) PTSD and risk of Alzheimer’s disease in Australian Vietnam Veterans: Amyloid and tau PET findings from AIBL-Vets. Alzheimers Dement13, 1094–1095.
Alzheimer’s and Dementia (2010) Contents. Alzheimers Dement6(3), A3–A4.
147.
Alzheimer’s and Dementia (2015) Contents. Alzheimers Dement11(7), A1–A2.
148.
American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders, 4th edition. American Psychiatric Association, Washington DC.
149.
PrinceM, AcostaD, ChiuH, ScazufcaM, VargheseM; 10/66 Dementia Research Group (2003) Dementia diagnosis in developing countries: A cross-cultural validation study. Lancet361, 909–917.
150.
PrinceM, AcostaD, FerriCP, GuerraM, HuangY, Llibre RodriguezJJ, SalasA, Luisa SosaA, WilliamsJD, DeweyME, AcostaI, JotheeswaranAT, LiuZ (2012) Dementia incidence and mortality in middle-income countries, and associations with indicators of cognitive reserve: A 10/66 Dementia Research Group population-based cohort study. Lancet380, 50–58.
151.
PrinaAM, MaystonR, WuYT, PrinceM (2019) A review of the 10/66 Dementia Research Group. Soc Psychiatry Psychiatr Epidemiol54, 1–10.
152.
HymanBT, PhelpsCH, BeachTG, BigioEH, CairnsNJ, CarrilloMC, DicksonDW, DuyckaertsC, FroschMP, MasliahE, MirraSS, NelsonPT, SchneiderJA, ThalDR, ThiesB, TrojanowskiJQ, VintersHV, MontineTJ (2012) National Institute on Aging-Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease. Alzheimers Dement8, 1–13.
153.
MontineTJ, PhelpsCH, BeachTG, BigioEH, CairnsNJ, DicksonDW, DuyckaertsC, FroschMP, MasliahE, MirraSS, NelsonPT, SchneiderJA, ThalDR, TrojanowskiJQ, VintersHV, HymanBT; National Institute on Aging; Alzheimer’s Association (2012) National Institute on Aging-Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: A practical approach. Acta Neuropathol123, 1–11.
154.
AlbertMS, DeKoskyST, DicksonD, DuboisB, FeldmanHH, FoxNC, GamstA, HoltzmanDM, JagustWJ, PetersenRC, SnyderPJ, CarrilloMC, ThiesB, PhelpsCH (2011) The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement7, 270–279.
155.
SperlingRA, AisenPS, BeckettLA, BennettDA, CraftS, FaganAM, IwatsuboT, JackCRJr, KayeJ, MontineTJ, ParkDC, ReimanEM, RoweCC, SiemersE, SternY, YaffeK, CarrilloMC, ThiesB, Morrison-BogoradM, WagsterMV, PhelpsCH (2011) Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement7, 280–292.
156.
CappaiR (2016) ‘From past to future’ -deciphering the molecular basis of Alzheimer’s disease through the pages of the Journal of Neurochemistry. J Neurochem139(Suppl 2), 215–223.
157.
NobiliF (2010) Functional biomarkers for Alzheimer’s disease. Open Nucl Med J2, 10–11.
158.
PerryG, CastellaniR (2014) Plaques and tangles: Birthmarks of the aging soul. Biochem Pharmacol88, 423–425.
159.
DeckerM, Muñoz-TorreroD (2016) Special Issue: “Molecules against Alzheimer”. Molecules21, 1736.
160.
BrayneC, MillerB (2017) Dementia and aging populations - A global priority for contextualized research and health policy. PLoS Med14, e1002275.
BjörkBC (2018) Evolution of the scholarly mega-journal, 2006-2017. PeerJ6, e4357.
163.
KurtzkeM, RomeroHR, Welsh-BohmerK (2013) Use of social media for recruitment in Alzheimer’s disease research. Alzheimers Dement9, P470.
164.
JemielniakD, MasukumeG, WilamoswkiM (2019) The most influential medical journals according to Wikipedia: Quantitative analysis. J Med Internet Res21, e11429.
165.
FrancisPT, CostelloH, HayesGM (2018) Brains for dementia research: Evolution in a longitudinal brain donation cohort to maximize current and future value. J Alzheimers Dis66, 1635–1644.
166.
ChawlaDS (2018) Sites warn against ‘predatory’ journals. Blacklists emerge after closure of popular Beall’s list. Nature555, 422–423.
167.
MancaA, MartinezG, CugusiL, DragoneD, DvirZ, DeriuF (2017) The surge of predatory open access in neurosciences and neurology. Neuroscience353, 166–173.
168.
MastenY, AshcraftA (2017) Due diligence in the open-access explosion era: Choosing a reputable journal for publication. FEMS Microbiol Lett363, fnx206.
169.
ShamseerL, MoherD, MaduekweO, TurnerL, BarbourV, BurchR, ClarkJ, GalipeauJ, RobertsJ, SheaBJ (2017) Potential predatory and legitimate biomedical journals: Can you tell the difference? A cross-sectional comparison. BMC Med15, 28.
