Rosa Ma et al. claimed in previous work that the protein TDP-43 represses cryptic exon inclusion in the gene UNC13A. We present here a formalization of that claim, stating that all things of class “TAR DNA binding protein” that are in the context of a thing of class “UNC13A” generally have a relation of type “inhibits” to a thing of class “inclusion of cryptic exon” in the same context.
Rosa Ma et al. [2] state that “Here we show that TDP-43 represses a cryptic exon splicing event in UNC13A.”. We present here a formalization of the main scientific claim from this quote by using a semantic template called the super-pattern [1].
In the context class we use the “UNC13A” (Q18036664) class from Wikipedia. In subject class, we use the ”TAR DNA binding protein” (Q21133247) from Wikidata. In the object class we used the “inclusion of cryptic exon” (VariO_0504) class from OBO ontology.
RDF code
This is our formalization as a nanopublication in TriG format:
