Abstract
Hemoglobin-Vesicles (HbV; diameter, 250 nm) are artificial O2 carriers encapsulating purified and concentrated human Hb solution in phospholipid vesicles (liposomes), and their safety and efficacy, as a transfusion alternative, have been studied. In this paper, we summarized the characteristics of HbV that have been clarified by the microcirculatory observations.
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