Abstract
Omega-3-fatty acids (n-3-FA) have various positive hemorheological effects in different clinical conditions. Ten male patients (mean age: 50 years) with ischemic heart disease and hyperlipoproteinemia were studied. They were treated by 10 capsules of Ameu (Omega Pharma, Berlin, Germany; 0.5 g salmon oil with 33% of n-3-FA) daily for two months. Besides routine laboratory parameters, hemorheological measurements (whole blood, plasma and serum viscosity) and exercise stress test with noninvasive hemodynamic control at baseline and after two months of treatment were carried out. Significant decrease (p < 0.01) of triglycerides (58%) was found. Cholesterol and plasma viscosity showed only a moderate decrease. Whole blood viscosity, exercise capacity and the measured hemodynamic parameters improved significantly (p < 0.05 or better). Our results show that this preparation can be useful in clinical practice because it has a beneficial effect on plasma lipids and on hemorheological and hemodynamic parameters.
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