Abstract
Blood rheology measurements (whole blood viscosity, plasma viscosity, hematocrit and fibrinogen) and fibrinolytic and metabolic tests (plasma fibrinolytic activity, C-peptide, total cholesterol, triglycerides) were performed in 40 obese subjects before and after one year of hypocaloric diet.
Our data show a slight decrease after weight loss of whole blood viscosity at 0.1 sec−1 but not at 1.3 and 94.5 sec−1. Hypocaloric diet did not affect plasma viscosity, plasma fibrinogen or plasma fibrinolytic activity despite a significant lowering of body mass index and C-peptide.
We conclude that in obesity there are metabolic, coagulation, fibrinolytic, and rheological changes that persist after weight loss.
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