Studies on hemorheological behaviours and blood ceil electrophoreses for cerebral vascular diseases

Abstract

A Study of cerebro-vascular diseases was carried out by testing hematocrit (X1), whole blood relative viscosity against saline (X2), whole blood reduced viscosity (X3) which was defined as (X2–1)/X1, plasma viscosity against saline (X4), erythrocyte electrophoretic time in their own plasma (X5), erythrocyte sedimentation rate (ESR, X6), ESR equation coefficient (X7), fibrinogen(X8), platelet electrophoretic time in their own plasma(X9), ADP inducing platelets and erythrocytes to produce slow percentages in electrophoretic behaviors (X10 and X11) for ischemic strokes (IS), hemorrhagic strokes (HS) and other relative disorders. The pathogenesis of IS was partially connected to the abnormality in hemorheology according to the increases of X1–X11 in the acute phase, and decreases of X1–X5 and X8 during the following periods since onset till 1–2 weeks, 3–6 months and 1–2 Years. Hemodilution was suggested in acute phase for IS patients and a injective preparation extracted from a Chinese traditional herb named DANGSHENG obtained better results than the low molecular weight dextran. A compound decoct ion of Chinese traditional herbs named PUYANHUAWUTANG, showed better results than routine measures to treat IS sequela. Some aspects of hemorheology differences and identity for IS and HS groups were discussed. The electrophoretic behaviors of erythrocytes and platelets and their ADP inducing slow-down were also discussed.