Abstract
In this study, hematocrit, plasma viscosity, fibrinogen, albumin, red cell aggregation and disaggregation threshold were measured on 20 control subjects and on 438 diabetic patients with and without vascular complications, with good and poor metabolic control. The rheological disturbances were characterized by a significant increase of red cell aggregation tendency at low shear rate, of red cell disaggregation thresholds, and by a significant increase of fibrinogen level and decrease of albumin level. The rheological disturbances observed may confirm the role of rheological phenomena in the genesis of diabetic microangiopathy.
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