Analysis of the passage of single blood cells in a single pore filtration system

Abstract

The sensitivity of the Single Erythrocyte Rigidometer (SER) has been improved and a new software program allows us the detailed analysis of subsequent passages. The flow of a single RBC can be differentiated into entry, transit, and exit phase. Application of stress models on RBC filtration resulted in pronounced effects of the entrance into the pore. Filtration of white blood cells increased the driving pressure gradient by a factor of more than 30 compared to RBC filtration.