Abstract
The modification of erythrocyte deformability, observed when one adds pentoxifylline in vitro, are studied using two methods. The filtration method (Hanss hemorheometer) allows, from filtration time measurements, to determine a filtration parameter. The viscometric method (Couette viscometer) allows, from shear-thinning measurements, to evaluate a viscometric parameter. These two parameters, which can characterize, to a certain extent, red blood cell deformability, are compared statistically. Furthermore, using those methods, the effect of pentoxifylline is evaluated on normal cells.
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