The differential enhancement pattern of contrast enhanced ultrasound and magnetic resonance imaging characteristics in hepatic angiomyolipoma: 7 case reports
Restricted accessResearch articleFirst published online February 23, 2019
The differential enhancement pattern of contrast enhanced ultrasound and magnetic resonance imaging characteristics in hepatic angiomyolipoma: 7 case reports
To compare the enhancement pattern of hepatic angiomyolipoma (HAML) on contrast enhanced ultrasound (CEUS) and magnetic resonance (MR).
METHODS:
The data of seven patients (females; age 28–52 years; mean, 42 years) with histologically proven HAMLs were retrospectively reviewed. All patients underwent CEUS and MR examination. The images were analyzed by two experienced doctors who blinded to the clinical and pathological information of cases.
RESULTS:
The mean diameter of the nodule was 5.7 cm (range: 3.2–10 cm). Histopathologic results revealed 4 nodules to be myomatous type and 3 nodules to be mixed type. All nodules showed hyperenhanced during arterial phase on both CEUS and MRI. During portal and delayed phase, washout was more showed on MRI (5/7, 71.4%) than on CEUS (2/7, 28.6%).
CONCLUSIONS:
There is discrepancy of enhancement pattern between CEUS and MRI. The quick wash-in and sustained hyperenhancement on CEUS may be helpful for the diagnosis of HAML.
IshakK.G., Mesenchymal tumors of the liver. In: OkudaK., PetersR.L., eds., Hepatocellular Carcinoma. New York: John Wiley and Sons, 1976, pp. 247–307.
2.
LiuW., MengZ., LiuH., LiW., WuQ., ZhangX., ChangyongE., Hepatic epithelioid angiomyolipoma is a rare and potentially severe but treatable tumor: A report of three cases and review of the literature, Oncol Lett11 (2016), 3669–3675.
3.
ZengJ.P., DongJ.H., ZhangW.Z., WangJ., PangX.P., Hepatic angiomyolipoma: A clinical experience in diagnosis and treatment, Dig Dis Sci55 (2010), 3235–3240.
4.
TakayasuK., ShimaY., MuramatsuY., MoriyamaN., YamadaT., MakuuchiM., HirohashiS., Imaging characteristics of large lipoma and angiomyolipoma of the liver. Case reports, Cancer59 (1987), 916–921.
5.
BartolottaT.V., RunzaG., MinerviniM. and Midiri, Hepatic angiomyolipoma: Contrast-enhanced pulse inversion US in a case, Radiol Med105 (2003), 514–518.
6.
TanY., XieX., LinY., HuangT., HuangG., Hepatic epithelioid angiomyolipoma: Clinical features and imaging findings of contrast-enhanced ultrasound and CT, Clin Radiol72 (2017), 339.e1–339.e6.
7.
LeeS.J., KimS.Y., KimK.W., KimJ.H., KimH.J., LeeM.G., YuE.S., Hepatic angiomyolipoma versus hepatocellular carcinoma in the noncirrhotic liver on gadoxetic acid-enhanced MRI: A diagnostic challenge, AJR Am J Roentgenol207 (2016), 562–570.
8.
WangC.P., LiH.Y., WangH., GuoX.D., LiuC.C., LiuS.H., GaoX.D., QuJ.H., LiuZ., ChangX.J., LuY.Y., ZengZ., LouM., YangY.P., Hepatic angiomyolipoma mimicking hepatocellular carcinoma: Magnetic resonance imaging and clinical pathological characteristics in 9 cases, Medicine (Baltimore)93 (2014), e194.
9.
LiR., TangC.L., CaiP., MaK.S., ZhangX.H., DingS.Y., ZhangY., GuoD.Y., YanX.C., Comparison of CT and contrast-enhanced ultrasound findings in hepatic angiomyolipoma with pathological correlations, Abdom Radio (NY)41 (2016), 248–225.
10.
ClaudonM., DietrichC.F., ChoiB.I., CosgroveD.O., KudoM., NolsøeC.P., PiscagliaF., WilsonS.R., BarrR.G., ChammasM.C., ChaubalN.G., ChenM.H., ClevertD.A., CorreasJ.M., DingH., ForsbergF., FowlkesJ.B., GibsonR.N., GoldbergB.B., LassauN., LeenE.L., MattreyR.F., MoriyasuF., SolbiatiL., WeskottH.P. and XuH.X., World Federation for Ultrasound in Medicine; European Federation of Societies for Ultrasound, Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver-Update 2010: A WFUMB-EFSUMB Initiative in Cooperation with Representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS, Ultrasound Med Biol39 (2013), 187–210.
11.
KamimuraK., NomotoM., AoyagiY., Hepatic angiomyolipoma: Diagnostic findings and management international journal of hepatology, Int J Hepatol (2012), 410781.
12.
YangX., LiA., WuM., Hepatic angiomyolipoma: Clinical, imaging and pathological features in 178 cases, Med Oncol30 (2013), 416.
13.
TsuiW.M., ColombariR., PortmannB.C., BonettiF., ThungS.N., FerrellL.D., NakanumaY., SnoverD.C., Bioulac-SageP., DhillonA.P., Hepatic angiomyolipoma: A clinicopathologic study of 30 cases and delineation of unusual morphologic variants, Am J Surg Pathol23 (1999), 34–48.
LiR., TangC.L., ZhangY., MaK.S., ZhangX.H., GuoD.Y., TanX.C., Diagnosis of hepatic angiomyolipoma by combination of baseline and contrast-enhanced ultrasound—a prospective study in non-cirrhotic patients, PLoS One10 (2015), e0132290.
16.
JiJ.S., LuC.Y., WangZ.F., XuM., SongJ.J., Epithelioid angiomyolipoma of the liver: CT and MRI features, Abdom Imaging38 (2013), 309–314.
17.
KimR., LeeJ.M., JooI., LeeD.H., WooS., HanJ.K., ChoiB.I., Differentiation of lipid poor angiomyolipoma from hepatocellular carcinoma on gadoxetic acid-enhanced liver MR imaging, Abdom Imaging40 (2015), 531–541.
18.
YueW.W., WangS., XuH.X., SunL.P., GuoL.H., BoX.W., LiX.L., ZhaoC.K., WangD., LiuB.J., Parametric imaging with contrast-enhanced ultrasound for differentiating hepatocellular carcinoma from metastatic liver cancer, Clin Hemorheol Microcirc64 (2016), 177–188.
19.
SchellhaasB., WaldnerM.J., GörtzR.S., VitaliF., KielischC., PfeiferL., StrobelD., JankaR., NeurathM.F., WildnerD., Diagnostic accuracy and interobserver variability of Dynamic Vascular Pattern (DVP) in primary liver malignancies - A simple semiquantitative tool for the analysis of contrast enhancement patterns, Clin Hemorheol Microcirc66 (2017), 317–331.
20.
KuramotoK., BeppuT., NamimotoT., ., Hepatic angiomyolipoma with special attention to radiologic imaging, Surg Case Rep1 (2015), 38.
