Joint Meeting The European Society for Clinical Hemorheology and Microcirculation The International Society for Clinical Hemorheology The International Society of Biorheology Krakow,Poland July 2-6,2018

Monday, July 2nd 12.00–18.00 Registration 18.00–19.30 Opening Ceremony 20.00–21.30 Welcome Reception Tuesday, July 3rd 9.00–10.00 ESCHM Plenary Lecture (L1) Chair: Jean-Frédéric Brun Lecture: Philippe Connes Blood rheology: From exercise responses to sickle cell disease pathophysiology 10.00–10.30 Coffee Break 10.30–12.00 Symposia S1–S3/Free Communications O1–O2 S1: VESSELS AND HEMORHEOLOGY Chairs: Kalman Toth and Norbert Nemeth S1-1 Hemorheological parameters and mortality in critically ill patients Beata Csiszar, Kinga Totsimon, Peter Kenyeres, Kalman Toth, Zsolt Marton S1-2 Leukocyte antisedimentation rate (LAR) and pituitary adenylate cyclase-activated polypeptid (PACAP) in polytrauma and burn victims. A preliminary study Csaba Loibl, Csaba Csontos, Livia Szelig, Lajos Bogar, Patricia Kovacs, Andrea Pankaczi, Szilard Rendeki, Martin Rozanovic, Marianna Matancic, Timea Nemeth, Beata Lelesz, Jozsef Nemeth, Attila Miseta, Dora Reglodi, Andrea Tamas S1-3 Do AB0 and Rh blood groups influence hemorheological parameters in vascular patients? Katalin Koltai, Dóra Endrei, Gábor Késmárky, Katalin Biró, Zsolt Márton Pécs, Gergely Fehér, Dávid Kovács, Imre Boncz, Antal Tibold, Kálmán Tóth S1-4 Applications of finite element analysis in clinical hemorheology Peter Varga, Sz. Javor, G. Jancso, A. Gedei, P Maroti, G. Balazs University of Debrecen Hungary S1-5 Effects of ischemia-reperfusion and various surgical preconditioning maneuvers on micro-rheological and microcirculatory parameters Norbert Nemeth, Gabor Varga, Balazs Szabo, Csaba Korei, Bela Turchanyi, Katalin Peto S1-6 Renal ischemia-reperfusion-induced micro-rheological and microcirculatory alterations and their influenceability by remote organ ischemic preconditioning Gabor Varga, Kitti Nagy, Noemi Pal, Gabor Nadubinszky, Balazs Szabo, Bence Tanczos, Viktoria Somogyi, Adam Deak, Katalin Peto, Norbert Nemeth S2: PLATELET ADHESION Chairs: Shinya Goto and Terumitsu Hasebe S2-1 Biologically validated model of platelet adhesion under blood flow conditions Shinya Goto S2-2 Glycoprotein distribution of surface-induced platelet activation on medical materials by electron microscopy technology Masamitsu Nakayama, Terumitsu Hasebe, Shunto Maegawa, Kenta Bito, Tomohiro Matsumoto, Tetsuya Suzuki S2-3 Hemorheological effects of mechanical stress on whole blood of patients with prosthetic heart valve failure Toru Maruyama, Chiharu Yoshida, Kei Irie, Shohei Moriyama, Taku Yokoyama, Mitsuhiro Fukata, Takeshi Arita, Keita Odashiro, Koichi Akashi S2-4 Platelet adhesion studies of implantable long-term use Fontan pump biomaterials Bryan Good, Clare McHugh, Keefe Manning, William Weiss, Chris Siedlecki S2-5: Development of hemocompatible materials for blood contacting devices by physical and chemical surface modification Terumitsu Hasebe, Masamitsu Nakayama, Shunto Maegawa, Kenta Bito, Tomihiro Matsumoto, Tetsuya Suzuki S3: ADVANCES IN HEMORHEOLOGICAL MEASUREMENTS-1 Chairs: Sehyun Shin and Sung Yang S3-1 Holotomography techniques for imaging 3D label-free imaging of cells and tissues Yong Keun Park S3-2 A microfluidic device for simultaneous measurement of blood viscosity, hematocrit, and deformability Byung Jun Kim, Sung Yang S3-3 Deformability measurement of continuous soft particles by lattice Boltzmann method and its applications to rheological flow characteristics Joon-Sang Lee S3-4 A microfluidic platelet assaying device for function test and antiplatelet response test Sehyun Shin O1: CELLULAR RHEOLOGY AND BIOPHYSICS Chair: Peter Butler O1-1 Albumin solder covalently bound to a biodegradable polymer membrane: New approach to improve binding strength in laser tissue soldering Andrea Nies, Bernhard Hiebl O1-2 Circumferential alignment of smooth muscle cells in micro-tube environment Yang Jin, Linhong Deng O1-3 Subhaemolytic mechanical trauma increases RBC aggregation by altering cell electrochemistry Antony McNamee, Geoff Tansley, Michael Simmonds O1-4 Subhaemolytic mechanical damage alters erythrocyte behavior in subsequent low-shear flows Antony McNamee, Geoff Tansley, Michael Simmonds O1-5 Ultrafast imaging of cell elasticity with optical microelastography Guy Cloutier, Grasland-Mongrain, Ali Zorgani, Shoma Nakagawa, Simon Bernard, Lia Gomes Paim, Greg FitzHarris, Stefan Catheline O1-6 The effects of substrate stiffness on HUVEC adhesion with THP-1 cells and molecules associated with adhesion Yan Wenhua Zhang Tian, Zhang Kang, Qiu Juhui, Wang Guixue O2: CLINICAL HEMORHEOLOGY Chair: Jean-Frédéric Brun O2-1 Pilot clinical study of quantitative ultrasound spectroscopy measurements of erythrocyte aggregation within superficial veins of 50 volunteers Guy Cloutier, Boris Chayer, Louise Allard, Julian Garcia-Duitama O2-2 Rapid clinical assessment of the sublingual microcirculation – Visual scoring using microVAS in comparison to standard semi-automated analysis Joel Sardinha, Christian Lehmann O2-3 L-cysteine improves blood fluidity that has been impaired by acetaldehyde Ippo Otoyama, Tatsushi Kimura, Hironobu Hamada, Kiyokazu Sekikawa, Michinori Kamikawa, Teruki Kajiwara, Fumiya Aizawa, Yoshinobu Sato, Haruchi Namba O2-4 Hemorheological studies in a group of patients with Waldenström’s macroglobulinemia Anna Marcinkowska-Gapińska, Piotr Kowal, Włodzimierz Liebert O2-5 Adora2b receptor activation mediates flap protection from ischemia/reperfusion injury Pinar Ulker, Ozlenen Ozkan, Matteo Amoroso, Mutay Aslan, Filiz Ozcan, Ibrahim Bassorgun, Omer Ozkan O2-6 Purinergic regulation of erythrocyte enzyme activity Pinar Ulker, Nur Özen, Günel Abdullayeva, Sadi Köksoy, Nazmi Yaraş, Filiz Basrali 13.00–14.00 Poiseuille Gold Medal Award (L2) Ceremony and Lecture Laudatio: Herbert H Lipowsky Lecture: Axel R Pries Microvascular hemodynamics: System properties 14.15–15.45 Symposia S4-S7/Free Communications O3 S4: GLYCOCALYX – ITS STRUCTURE AND FUNCTION Chairs: John Tarbell and Hans Vink S4-1 Multilayer structures of the endothelial glycocalyx: barrier functions versus red cell hemodynamics FitzRoy Curry S4-2 Endothelial Surface Glycocalyx (ESG) components and ultra-structures revealed by Stochastic Optical Reconstruction Microscopy (STORM) Jie Fan, Yi Sun, Yifan Xia, John Tarbell, Bingmei Fu S4-3 In vivo studies of the enzymatic degradation and structure of the endothelial glycocalyx Herbert Lipowsky S4-4 The endothelial glycocalyx and control of microvascular flow and perfused capillary density Hans Vink S5: NOVEL MECHANISMS REGULATING BLOOD CELL RHEOLOGY Chairs: Brian Cooke and Tamas Alexy S5-1 Interaction of mesenchymal stem cells with platelets: Aid to targeting to tissue or thrombotic risk? Lozan Sheriff, Asma Alanazi, Lewis Ward, Julie Rayes, Mohammed Alassiri, Steve Watson, Gerard Nash S5-2 Malaria and babesiosis: Same rheopathobiology but different molecular mechanisms Brian Cooke S5-3 Form and function: erythrocyte responses to supra-physiological shears and circulatory support Michael Simmonds S5-4 Blood rheology, arterial stiffness, and clinical complications in diabetic patients with and without sickle-cell trait Sarah Skinner, Mor Diaw, Maïmouna Ndour Mbaye, Brigitte Ranque, Philomène Lopez, Malick Ndour, Fatou Gueye, Demba Diedhiou, Djiby Sow, Saliou Diop, Abdoulaye Samb, Vincent Pialoux, Philippe Connes S5-5 The importance of hemorheology in the design of continuous flow left ventricular assist devices Tamas Alexy S6: ADVANCES IN HEMORHEOLOGICAL MEASUREMENTS-2 Chairs: Sehyun Shin and Sung Yang S6–1 Optical study of red blood cells interactions in vitro mediated by different plasma components Alexander Priezzhev, Alexey Semenov, Andrei Lugovtsov, Kisung Lee, Christian Wagner S6-2 Effect of integrin glycoproteins inhibition on specific adsorption of cells adhesion macromolecules on red blood cell membrane: A microrheologic study Alexey Semenov, Andrei Lugovtsov, Kisung Lee, Alexei Myravyev, Sehyu Shin, Evgeny Shirshin, Alexander Priezzhev S6-3 Electrochemical impedance spectroscopy of blood for blood aggregation, sedimentation, and hematocrit Alexander Zhbanov, Sung Yang S6-4 Comparison of critical shear stress in RheoScan and adhesion force between RBCs measured in optical tweezer Sehyun Shin, Hoyoon Lee, Kisung Lee, Alexander Priezzhev S7: HEMORHEOLOGY AND BLOOD COAGULATION Chairs: Ursula Windberger and Resia Pretorius S7-1 Stress sweep tests on whole blood clots Ursula Windberger S7-2 The novel discovery of amyloid formation in fibrin(open) and how it affects hemorheology and blood coagulation Etheresia Pretorius S7-3 Multiscale mechanics of fibrin networks Cristina Martinez-Torres S7-4 Study of blood clotting mechanism by rheological and electrorheological methods Nadia Antonova, Ivan Ivanov S7-5 Influence of polymeric nanoparticles on the kinetics of coagulation of conserved blood Nadya Todorova, Nadia Antonova S7-6 What are conditions defining blood clot properties in some disorders Eugene Roitman, Alla Shabalina, Marine Tanashyan, Irina Kolesnikova O3: ENDOTHELIAL FUNCTION AND SHEAR STRESS Chairs: Markos Klonizakis and Guixue Wang O3-1 Arrangement and morphology of endothelial cells under the mechanical microenvironment changes after vascular stent implantation Tieying Yin, Yuzhen Ren, Ruolin Du, Yuhua Huang, Yazhou Wang, Guixue Wang O3-2 Blood Flow Regulates Zebrafish CVP Angiogenesis by Inducing ERK5 Signaling Guixue Wang O3-3 The role of Id1 in oscillatory shear stress-mediated endothelial lipid uptake Kang Zhang, Yidan Chen, Guixue Wang O3-4 Effect of DNA methyltransferase 1 in oscillatory shear stress-induced atherosclerotic vulnerable plaque formation Lu Huang, Desha Luo, Yuanhang Zhou, Kang Zhang, Juhui Qiu, Guixue Wang O3-5 The influence of hemodynamic changes on proliferation and adhesion of endothelial progenitor cells Jinxuan Wang, Li Xiao, Daming Sun, Yiming Zheng, Tieying Yin, Guixue Wang O3-6 Short term effects of the Mediterranean Diet in human microvascular function – comparison between older and younger healthy, sedentary adults Yingshan Liu, Marianne Milner, Markos Klonizakis 16.15–17.45 Symposia S8-S12 S8: GLYCOCALYX – ITS DIVERSITY Chair: Herbert Lipowsky S8-1 Surface glycocalyx mediates tumor cell metastasis Henry Qazi, Heriberto Moran, Limary Cancel, Mariya Mayer, Lance Munn, John Tarbell S8-2 Visualization of heparan sulfate proteoglycans in the glycocalyx and the perivascular space of 3-dimensional perfusable microvascular networks in microfluidic devices Sebastian Beyer, Anna Blocki, Roger D. Kamm S8-3 Integrin-mediated adhesion is lipid bilayer and glycocalyx dependent Seoyoung Son, Joseph Moroney, Peter Butler S8-4 Coupled dynamics of blood flow and endothelial glycocalyx: A large-scale molecular dynamics study Xi Zhuo Jiang, Kai H. Luo, Yiannis Ventikos S9: MOLECULAR AND MECHANICAL MARKERS OF VARIOUS PATHOLOGIES Chair: Małgorzata Lekka S9-1 Early stage of essential hypertension monitoring Kvetoslava Burda, Magdalena Kaczmarska, Maria Fornal, Franz Messerli, Jozef Korecki, Tomasz Grodzicki S9-2 Label-free methods in diagnostics and prognostics of malignant melanoma Tomasz Kobiela S9-3 Advanced vibrational imaging techniques to aid clinical research Tomasz P. Wrobel, Paulina Koziol, Natalia Piergies, Ewa Pieta, Czeslawa Paluszkiewicz, Maria Fornal, Tomasz Grodzicki, Wojciech Kwiatek S9-4 Effect of dietary carotenoids on erythrocytes from diabetic patients: A spectroscopic study Joanna Fiedor, Mateusz Przetocki, Grzegorz Gajos, Józef Korecki, Kvetoslav Burda S10: MiDAS MICROCIRCULATION MEETING (3M) Chairs: Christian Lehmann and Vladimir Cerny S10-1 Dynamic Contrast Enhanced Ultrasound (CEUS) of tissue transplants Ernst Michael Jung, Sebastian Geis, Andreas Kehrer, Philipp Edmund Lamby, Lukas Prantl S10-2 Assessment of glycocalyx Vladimir Cerny S10-3 Automated vs. visual video analyses – where is the future? Christian Lehmann S10-4 Is sodium a link between endothelial glycocalyx and microcirculation? David Astapenko, Vladimir Cerny S11: BEYOND RED CELL STIFFNESS Chairs: Jean-Frédéric Brun and Carlota Saldanha S11-1 RBC deformability: An exquisite homeostasis Jean-Frédéric Brun, Emmanuelle Varlet-Marie S11-2 Eryptosis or the death of a rigidified erythrocyte Etheresia Pretorius S11-3 Erythrocyte deformability under nitric oxide Influence Carlota Saldanha, Ana Silva-Herdade S11-4 The sickle cell: Far more than a rigid erythrocyte Philippe Connes, Elie Nader, Nicolas Guillot, Romain Fort, Berenike Möckesch, Nathalie Lemonne, Sophie Antoine-Jonville, Céline Renoux, Philippe Joly, Vincent Pialoux, Marie-Dominique Hardy-Dessources, Marc Romana S11-5 Signaling pathways in regulation of RBC microrheological properties by catecholamines Irina Tikhomirova, Alexei Myravyov, Elena Petrochenko S11-6 Complete dynamics of erythrocytes in shear flow: The story behind the term of deformability Simon Mendez, Luca Lanotte, Johannes Mauer, Franck Nicoud, Gerhard Gompper, Dmitry Fedosov, Manouk Abkarian S12: MACRO AND MICRO HEMORHEOLOGY IN VITRO AND IN VIVO Chairs: Michael Simmonds and Jon Detterich S12-1 The “tipping point” of mechanical stress on erythrocyte biology Michael Simmonds S12-2 Testing the sensitivity of red cell fragmentation and deformability measurements for shear-mediated mechanical damage Özlem Yalcin, Ali Cenk Aksu, Elif Ugurel, Selcuk Surucu S12-3 Discussion about high shear stress induced erythrocyte’s damage and lysis – Interpretation of hemolysis in cardiovascular devices based on our visualized erythrocytes’ behaviors Nobuo Watanabe, Takahiro Shimada, Nao Ikeda, Kousuke Igarashi S12-4 Mechanical sensitivity of blood in sickle patients on chronic blood transfusion – understanding erythrocyte exposure to chronic physiologic shear vs. chronic supra-physiologic but sub-hemolytic shear stress Jon Detterich, Silvie Siriany, Derek Ponce, Michael Simmonds S12-5 Drag-reducing polymer effects on macro- and microcirculation Marina Kameneva Wednesday, July 4 9.00–10.00 ISB Plenary Lecture (L3) Chair: Peter Butler Lecture: Frank J.Gijsen Biomechanics and atherosclerotic plaques progression 10.30–12.00 Symposia S13-S15/Free Communications O4-O5 S13: MICROCIRCULATION OF INNER ORGANS Chairs: Ernst Michael Jung and Pamela Zengel S13-1 Critical analysis of CEUS examinations of the liver in an interdisciplinary ultrasound department Franz Josef Putz, Anna Erlmeier, Niklas Verloh, Bernhard Banas, Christian Stroszczynski, Ernst Michael Jung S13-2 VTIQ and VTQ in combination with B-mode and color Doppler ultrasound improve classification of salivary gland tumors, especially for inexperienced physician Pamela Zengel, Florian Notter, Dirk Andre Clevert S13-3 CEUS perfusion imaging after ablation treatment in patients with prostate cancer: First results Isabel Wiesinger, Lukas Beyer, Philipp Wiggermann, Christian Stroszczynski, Ernst Michael Jung S13-4 Contrast-enhanced ultrasound (CEUS) and gallbladder diseases – a retrospective monocenter analysis of imaging findings with histopathological correlation G. Negrão de Figueiredo, K. Mueller-Peltzer, P. Zengel, E. Gresser, J. Rübenthaler, D.A. Clevert, München S13-6 New horizons for kidney imaging: Dynamic microvascularization in contrast-enhanced ultrasound (CEUS) Franz Josef Putz, Anna Erlmeier, Miriam Banas, Bernhard Banas, Ernst Michael Jung S14: CELL MECHANICS AND CELL MECHANOBIOLOGY - 1 Chairs: Taiji Adachi and Yukiko Matsunaga S14-1 Effect of physical environment on cell migration using microchannel device Toshiro Ohashi, Mazlee Bin Mazalan, Ma Ming, Jennifer H. Shin S14-2 Protein kinase C𝛼 translocation in endothelial cells in response to mechanical stimulus Susumu Kudo, Toshihiro Sera, Masataka Arai S14-3 Hydrostatic pressure-induced DNA breaks in chondrocytes and its relationship with chromatin architecture Koichiro Maki, Katsuko Furukawa, Takashi Ushida S14-4 In situ, fluorescence lifetime-based measurements of cell membrane micromechanics Seoyoung Son, Hari Muddana, Changjin Huang, Sulin Zhang, Peter Butler S15: HEMODYNAMIC FUNCTIONALITY OF RED BLOOD CELLS IN BLOOD MICROCIRCULATION: EXPERIMENTS AND MODELING Chairs: Saul Yedgar and Ming Dao S15-1 Biomechanics of red cell diseases Ming Dao S15-2 Microvascular blood flow peculiarities in cancer Irina Tikhomirova, Yulia Malysheva, Nikolay Kislov, Mihail Ryabov S15-3 Shape and dynamics of red blood cells in microvessels Johannes Mauer, Felix Reichel, Jochen Guck, Gerhard Gompper, Dmitry Fedosov S15-4 Hemodynamic functionality of transfused red blood cells in the microcirculation of blood recipients Gregory Barshtein, Axel Pries, Neta Goldschmidt, Orly Zelig, Dan Arbell, Saul Yedgar S15-5 Red blood cell aggregate flow characteristics in bifurcating microchannels Efstathios Kaliviotis, Joseph Sherwood, Stavroula Balabani O4: RED BLOOD CELL DEFORMABILITY Chairs: Edgar O’Rear and Philippe Connes O4-1 Beta-estradiol and ethinylestradiol enhance RBC deformability dependent on their blood concentration Paulo Farber, Teresa Freitas, Carlota Saldanha, Ana Silva-Herdade O4-2 Dual mechanical characterization of red blood cells: Role of surface area, internal viscosity and membrane rigidity Céline Renoux, Magali Faivre, Amel Bessaa, Philippe Joly, Philippe Connes O4-3 Proteomic analysis of the role of adenylyl cyclase-cAMP pathway in red blood cell mechanical response Özlem Yalcin, Elif Ugurel O4-4 The oxygen scan: continuous measurement of red blood cell deformability with oxygen gradient ektacytometry to monitor disease severity and treatment effect in sickle cell disease Minke Rab, Brigitte van Oirschot, Tesy Merkx, Annet van Wesel, Sisto Hendriks, Jan de Zoeten, Osheiza Abdulmalik, Martin Safo, Birgitta Versluijs, Roger Schutgens, Gerard Pasterkamp, Eduard van Beers, Richard van Wijk O4-5 Nitric oxide regulates human erythrocyte deformability through adjusting band phosphorylation status in hypoxia Yajin Zhao, Xiang Wang O4-6 Hypoxia: The best stimulator that increases shear-induced response of red blood cells Elif Ugurel, Ali Cenk Aksu, Senol Piskin, Özlem Yalcin O5: FLOW VISUALIZATION AND MODELING Chairs: Sung Yang and Efstathios Kaliviotis O5-1 Velocity and erythrocyte aggregation characteristics for surface tension-driven flow of blood in rectangular microfluidic channels Dimitris Pasias, Efstathios Kaliviotis O5-2 A new approach of blood viscosity: Hemodynamic viscosity Tilly Alexandre O5-3 Evaluation and comparison of haemodynamic parameters of vascular end-to side anastomoses Balazs Gasz, Peter Varga, Peter Maroti, Gabor Jancso O5-4 Similarities in erythrocyte senescence and microfluidic high shear environment Damage James Buerck, Dimitrios Papavassiliou, Trevor Snyder, David Schmidtke, Edgar O’Rear O5-5 Investigation of bright collapsing ring by Lattice Boltzmann method Young Woo Kim, Chan Soo Min, Joon Sang Lee 13.00–14.00 ISCH Medal Award (L4) Ceremony and Lecture Laudatio: Kalman Toth Lecture: Brian M. Cooke The rheopathobiology of malaria and babesiosis 14.15–15.45 Symposia S16–S18/Free Communications O6 S16: SPECIAL SYMPOSIUM TO CELEBRATE THE CENTENNIAL OF DISTINGUISHED PROFESSOR YUAN-CHENG B. FUNG (1) Chairs: Linhong Deng and Li Yang S16-1 Morphogenesis and mechanobiology of airway smooth muscle cells on 3D tubular micropatterns as mechanism of bronchial airway development Linhong Deng, Yang Jin, Mingzhi Luo, Lei Liu, Jingjing Li S16-2 Glycosylation is a strong molecular determinant of MUC5AC rheology in airway mucus at both single protein and bulk solution levels Lei Liu, Mingzhi Luo, Yan Pan, Jingjing Li, Linhong S16-3 Dynamics of neutrophil transmigration mediated by beta-2 integrin via P- and E-selectins Yan Zhang, Mian Long S16-5 Influence of different rhythms sound wave to serotonin concentration in rats hippocampus Yang Ren, Zhidan Deng S17: RHEOLOGY AND MICROCIRCULATION Chairs: Lucas Prantl and Gerhard Pindur S17-1 Longitudinal analysis of thrombin generation biomarkers in venous thromboembolism Gerhard Pindur, Aida Beye, Bernhard Stephan, Harald Helling S17-2 Comparison of PIRADS 3 lesions with histopathological findings after MRI-ultrasound fusion targeted biopsy of the prostate in a real-world setting Boris Schlenker, Maria Apfelbeck, Christian G. Stief, Dirk-Andre Clevert S17-3 Does acoustic radiation force Elastography help to improve the diagnostic value of ultrasound in the preoperative characterization of tumors of the parotid gland? Pamela Zengel, Florian Notter, Dirk Andre Clevert S17-4 Technologies for adipose stem cell isolation L. Prantl, V. Brebant, S. Klein, A. Anker, C Strauss, O. Felthaus S17-5 Blood rheology in breast and gynecologic cancer patients at primary diagnosis and stage of cancer progression O. Schelkunov, P. Tsikouras, R. Csorba, W. Rath, G-F. von Tempelhoff S17-6 First experiences with a clinical work-flow integrated CAM Assay in Patients with oral squamous cell carcinoma P. Kauffmann, M. Troeltzsch, P. Brockmeyer, H. Bohnenberger, P. Stroebel, M. Manzke, R. Cordesmeyer, H. Schliephake, L. Prantl, T. Aung S18: NANOSTRUCTURES IN DISEASE AND HEALTH Chairs: Květoslava Burda and Marek Cyrklaff S18-1 Malaria parasites, host-erythrocytes and blood circulation Marek Cyrklaff S18-2 Polyhedrocytes in type 2 diabetes Grzegorz Gajos, Aleksander Siniarski, Joanna Natorska, Michał Ząbczyk, Jakub Siudut, Aneta Undas S18-3 Differentiation between various melanomas based on biophysical characterization of their properties Justyna Bobrowska, Joanna Pabijan, Kamil Awsiuk, Jakub Rysz, Andrzej Budkowski, Małgorzata Lekka S18-4 Endothelial nanomechanics in vascular diseases – an ex vivo AFM nanoindentation study Marta Targosz-Korecka, Magdalena Jaglarz, Katarzyna Małek-Ziętek, Stefan Chłopicki, Marek Szymoński O6: RED BLOOD CELL AGGREGATION Chairs: Dong-Guk Paeng and Norbert Nemeth O6-1 Alterations in RBC aggregation during incubation in glucose solution Alicja Szołna-Chodór, Paulina Grychtal, Bronisław Grzegorzewski O6-2 Numerical study of red blood cell aggregation kinetics under sinusoidal pulsatile flow Cheong-Ah Lee, Soohong Min, Minho Lee, Dong-Guk Paeng O6-3 Structure and stability of red blood cell aggregates in model flows Thomas Podgorski, François Yaya, Gwennou Coupier, Daniel Flormann, Christian Wagner O6-4 Covalent immobilization of biomolecules on stent materials through mussel adhesive protein coating to promote cell adhesion Yi Wang, Hualin Lan, Tieying Yin, Yazhou Wang, Guixue Wang O6-5 The changes of vascular mechanical properties of porcine coronary artery after stent implantation Yinping Zhao, Lili Tan, Xiaojuan Zhang, Juhui Qiu, Guixue Wang Thursday, July 5th 9.00–10.00 ISCH Plenary Lecture (L5) Chair: Gerard Nash Lecture: Sehyun Shin Microfluidic platelet function assays 10.30–12.00 Symposia S19-S23 S19: INTERACTION OF BLOOD CELLS/TISSUE ENGINEERING Chairs: Friedrich Jung and Anna Blocki S19-1 Long-term prognosis of coronary microvascular dysfunction Remzi Anadol, Tommaso Gori S19-2 AD-MSCs change their morphology and secretion profile as a response to changes in substrates’ elastic properties in combination with inflammatory stimuli M. Papagrigorakes, N. Chirico, A. Blocki, A. Neffe, F. Jung, N. Ma, A. Lendlein S19-3 Thrombogenicity testing of polymers: Round-robin study to assess inter-center variability Steffen Braune, Claudia Sperling, Manfred F. Maitz, Ulrich Steinseifer, Johanna Clauser, Bernhard Hiebl, Stefanie Krajewski, Hans P. Wendel, Friedrich Jung S19-4 The controversial origin of pericytes – implications for cell-based therapies Anna Blocki, Sebastian Beyer, Friedrich Jung, Michael Raghunath S19-5 A facile way to achieve biomimetic laminin networks on substrates Thanga Bhuvanesh, Rainhard Machatschek, Burkhard Schulz, Yan Nie, Nan Ma, Andreas Lendlein S19-6 Medical compression stockings reduce hypertension of nailfold capillaries at the toe of patients with chronic venous insufficiency Michael Jünger, Anja Oelert, Manuela Kittel, Hermann Haase, Martin Hahn S20: FLOW VISUALIZATION OF CARDIOVASCULAR DEVICES Chairs: Keefe Manning and Ajit Yoganathan S20-1 Visualization of cardiac flows: In vitro, in vivo, and in silico studies Immanuel David Madukauwa-David, Vrishank Raghav, Prem A. Midha, Vahid Sadri, Phillip Trusty, Zhenglun Wei, Ajit Yoganathan S20-3 Leveraging fluid dynamic measurements to improve cardiac device design Keefe Manning S20-4 Hemodynamics assessment of new transcatheter bi-caval valves in the interventional treatment of tricuspid regurgitation Munirah Binte Ismail, Foad Kabinejadian, Yen Ngoc Nguyen, Hwa Liang Leo S21: MACRO AND MICRORHEOLOGICAL BLOOD CHARACTERISTICS UNDER PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS Chairs: Nadia Antonova and Eugene V. Roitman S21-1 Analysis of the cutaneous blood flow responses and microvascular tone regulation in patients with type 2 diabetes mellitus. Relationship to rheological properties of blood Nadia Antonova, Vasilka Paskova, Irena Velcheva, Nino Chaushev, Sergey Podtaev, Kirill Tsiberkin S21-2 Relationship between rheological properties of blood and leukocyte adhesion under flow conditions in patients with type 2 diabetes mellitus Anika Aleksandrova, Nadia Antonova, Alexei Muravyov, Ekaterina Uzikova S21-3 Hemorheological disturbances as the thrombosis-developing factor Eugene Roitman, Alla Shabalina, Marine Tanashyan, Irina Kolesnikova S21-5 Local carotid stiffness in patients with cerebral small vessel disease. Relation to blood viscosity Irena Velcheva, Nadia Antonova, Tsocho Kmetski, Galina Tsonevska, Anika Alexandrova S22: THE GLYCOCALYX – ITS ROLE IN DISEASE Chairs: John Tarbell and Hans Vink S22-1 Role of the glycocalyx in atheroprotective vs. atheropermissive endothelium function Eno Ebong, Ian Harding, Solomon Mensah, Ming Cheng, Ronodeep Mitra S22-2 Loss of the retinal endothelial glycocalyx in diabetes Norman R. Harris, Wendy Leskova, Haley Peace, Patsy R. Carter, Randa Eshaq S22-3 Endothelial glycocalyx restoration by growth factors in diabetic kidney disease Karen Onions, Sara Desideri, Nicola Buckner, Monica Gamez, Gavin Welsh, Andrew Salmon, Simon Satchell, Rebecca Foster S22-4 Modification of renal macrophage signalling via MCP-1 inhibition reduces albuminuria in diabetic nephropathy Bernard van den Berg, Margien Boels, Angela Koudijs,Cristina Avramut, Wendy Sol, Annemarie van Oeveren-Rietdijk, Hetty de Boer, Cees van Kooten, Dirk Eulberg, Johan Van der Vlag, Daphne IJpelaar, Ton Rabelink S23: SPECIAL SYMPOSIUM TO CELEBRATE THE CENTENNIAL OF DISTINGUISHED PROFESSOR YUAN-CHENG B. FUNG (2) Chairs: Linhong Deng and Li Yang S23-1 Investigation on energy characteristic of red blood cell deformability: A quantitative analysis of extending and retracting curves based on Atomic Force Microscopy Dong Chen, Xiang Wang S23-3 Nitric oxide regulates human erythrocyte deformability through regulating band 3 phosphorylation status in hypoxia Yajin Zhao, Xiang Wang S23-4 Development history, progress and future prospects of biorheology and biomechanics in Chongqing University Wang Guixue S23-5 Zebrafish caudal vein formation is flow shear stress dependent Lin Wen 13.00–14.00 Fahraeus Gold Medal Award (L6) Ceremony and Lecture Laudatio: Nadia Antonova Lecture: Carlota Saldanha Multifunctional life of the erythrocyte 14.15–15.45 Symposia S24-S26/Free Communications O7-O8 S24: CLINICAL STUDIES IN HEMORHEOLOGY Chairs: Byoung K. Lee and KyuChang Won S24-1 The role of hemorheologic changes in diabetic microvascular complications Jun Sung Moon, Kyu Chang S24-2 RBC abnormalities presented with clinical diagnostic variables in sepsis Choon Hak Lim, Jung Min Youn, Eun Gi Ko S24-3 Decrease myocardial perfusion associated with hemorheologic parameters in patients with type 2 Diabetes Byoung Kwon Lee, Minhee Cho, Sehyun Shin S24-4 Erythrocyte aggregation and deformability as factors determining capillary blood flow in patients with arterial hypertension Andrei Lugovtsov, Alexey Semenov, Yuri Gurfinkel, Petr Ermolinskiy, Anastasiya Maslyanitsina, Nikita Povalyaev, Larisa Dyachuk, Elena Pavlikova, Alexander Priezzhev S25: CLINICAL MICROCIRCULATION Chairs: Dirk Andre Clevert and Isabel Wiesinger S25-1 Postoperative control of vascularized lymph node transfer (VLNT) for the treatment of extremity lymphedema: Ultrasound guided lymph node monitoring using contrast enhanced ultrasound (CEUS) T. Aung, C. Taeger, S. Geis, A. Kehrer, L. Prantl, E.M. Jung S25-2 The Use of Indocyanine green (ICG) imaging technique in the groin lymphocele microsurgical resection M. Ranieri, C.D. Taeger, S. Geis, S. Klein, P. Lamby, D. Schiltz, K. Pfister, L. Prantl, V. Hoesl, T. Aung S25-3 Significance of high-resolution Color-Duplex-Ultrasound (CDU) designing adipocutaneous, fasciocutaneous and chimeric perforator flaps A. Kehrer, S. Geis, C. Taeger, N. Platz Batista da Silva, E.M. Jung, L. Prantl, V. Mandlik S25-4 Influence of systemic vasopressor drugs and fluid administration on microcirculation in free tissue transfer A. M. Anker, L. Prantl, C. Strauss, V. Brébant, S. M. Klein S25-5 ICG-fluorescence-angiography– a new indication in revascularized digits and toes C. Strauss, A. Anker, L. Prantl, N. Heine, C. Wenzel, S. Geis, T. Aung, V. Brébant S25-6 ICG-fluorescence-angiography in revascularized digits – first results of a standardized clinical study C. Strauss, A. Anker, V. Brébant, L. Prantl, D. Schiltz, R. Kemper, S. Geis, T. Aung Regensburg, Germany S26: RED BLOOD CELL NITRIC OXIDE/RHEOLOGY Chairs: Michael Simmonds and Philippe Connes S26-1 Nitric oxide synthase activity at various levels and durations of shear stress Michael Simmonds S26-2 Erythrocyte nitric oxide dependent of acetylcholinesterase receptor Carlota Saldanha, Ana Silva-Herdade S26-3 Hydroxyurea therapy modulates sickle cell anemia red blood cell physiology by acting as a nitric oxide donor: Impact on RBC deformability, oxidative stress and nitric oxide synthase activity Elie Nader, Marijke Grau, Romain Fort, Nicolas Guillot, Cyril Martin, Giovanna Cannas, Solène Poutrel, Arnaud Hot, Alexandra Gauthier, Wilhelm Bloch, Marc Romana, Philippe Connes S26-4 The multifaceted role of nitrite and the epigenetic nitric oxide donor, RRx-001 on erythrocyte deformability Selma Cırrık, Özlem Yalcin O7: DISEASE AND HEMORHEOLOGY Chairs: Gerard Nash and Sajad Ahmadizad O7-1 Do changes in bone marrow pressure contribute to the egress of cells (RBC, reticul.) from bone marrow? Zbigniew Dąbrowski, Anna Marchewka, Aneta Teległów, Maria Fornal O7-2 Platelet-derived extracellular vesicles promote the adhesion of flowing neutrophils to endothelial cells Sahithi Kuravi, Paul Harrison, G.Ed Rainger, Gerard Nash O7-3 Morphological and metabolic abnormalities of erythrocytes as risk factors for Alzheimer’s Disease Francesco Misiti, Marco Girasole, Simone Dinarelli O7-4 Effects of two different high intensity interval training protocols on hemorheological variables in hypertensive patients Sajad Ahmadizad, Mohammad Soltani, Neda Aghaei Bahmanbeglou O7-5 Sedentarity status as a regulator of the optimal hematocrit: Involvement of red cell deformability? Jean-Frederic Brun, Emmanuelle Varlet-Marie, Bénédicte Marion, Céline Roques, Marlène Richou, Eric Raynaud de Mauverger O7-6 The effects of n-6 polyunsaturated free fatty acids dietary intake on hemorheology and endothelium–dependent microvascular function Ines Drenjančević O8: BIORHEOLOGY AND BIOTECHNOLOGY-1 Chair: Guixue Wang O8-1 Fabrication of gradient nanofibrous scaffold for interface tissue engineering Li Yang, Peixing Chen, Yu Zhang O8-2 Tanshinone can inhibit inflammation and angiogenesis in several chondrocytic cells Li Yang, Yu Zhang, Peixing Chen O8-3 The preliminary research of mechanical compress damage on neurons induced by hematoma Wei Wang, Yin Yin, Jun Wang, Tieying Yin, Yazhou Wang, Guixue Wang O8-4 Hemodynamic analysis of cerebral aneurysms: Suggestions for surgical options Shicheng He Friday, July 6th 9.00–10.00 Plenary Lectures in Tribute to Prof. Oguz Baskurt (L7) Chair: Jean-Frédéric Brun Özlem Yalçın Blood rheology as a determinant of blood flow: Physiological and clinical aspects Jon Detterich Red blood cell rheology and nitric oxide production: A scientist on the forefront 10.30–12.00 Symposia S27-S29/Free Communications O9 S27: CELL MECHANICS AND CELL MECHANOBIOLOGY – 2 Chairs: Toshiro Ohashi and Susumu Kudo S27-1 Effect of local tensile stress field on bone matrix and cell alignment: An in vitro study Taiji Adachi, Kei-ichi Ishikawa, Junko Sunaga, and Yoshitaka Kameo S27-2 Blood vessel on a chip - 3D vs. 2D Yukiko Matsunaga S27-3 Mechanotargeting of nanoparticles to atherogenic endothelium Pouria Fattahi, Sulin Zhang, Justin Brown, Yin-Ting Yeh, Peter Butler S27-4 The roles of vessel pulsation and dilation in clearing extracellular waste from the brain Ravi Kedarasetti, Bruce Gluckman, Patrick Drew, Francesco Costanzo S28: RHEOLOGY AND MICROSTRUCTURE OF CELLULAR BLOOD FLOW Chairs: Masako Sugihara-Seki and Ken-ichi Tsubota S28-1 Effect of internal viscosity on suspension rheology of red blood cells Naoki Takeishi, Marco Rosti, Yohsuke Imai, Shigeo Wada, Luca Brandt S28-2 Hemolytic behavior of human red blood cells caused by osmotic pressure difference – Visualization of hemoglobin behavior by use of light absorption characteristics Ryoko Otomo, Akihito Morita, Kiyoshi Bando S28-3 Effects of red blood cells on blood flow in micro vessel network: In vitro experiment and computer simulation Ken-ichi Tsubota, Yuya Kodama, Ryoma Kanai S28-4 Capillary flow imaging with genetically-engineered red blood cells in the living animal brain Yuika Kurihara, Takuma Sugashi, Kazuto Masamoto S28-5 Fluid dynamical study of preferential distributions of blood cell components in microchannel flows Masako Sugihara-Seki, Nozomi Takinouchi, Tenki Onozawa, Junji Seki S29: ROLE OF GASOTRANSMITTERS (NO, CO AND H ₂ S) IN BLOOD CELL FUNCTIONS AND THE MOLECULAR MECHANISMS OF THEIR MICRORHEOLOGY ALTERATIONS Chairs: Carlota Saldanha and Eugene Roitman S29-1 Leukocytes as a link between inflammation and erythrocyte nitric oxide Ana Silva-Herdade, Carlota Saldanha S29-2 Contribution of fibrinogen to erythrocyte scavenger nitric oxide Carlota Saldanha S29-3 Role of nitrogen oxide and hydrogen sulfide as signaling molecules in the change of red blood cell microrheology in patients with type 2 diabetes mellitus Svetlana Bulaeva, Alexei Muravyov, Irina Tikhomirova, Pavel Avdonin S29-4 Change of microrheological characteristics of erythrocytes under the influence of donors of gasotransmitters NO and H S: In vitro study Yulia Malysheva, Alexei Muravyov O9: BIORHEOLOGY AND BIOTECHNOLOGY-2 Chair: Jinxuan Wang O9-1 Proteomic analysis of ApoE-/- mice with disturbed flow model Li Tianhan, Wang Guixue O9-2 Effects of suspension state on the biological behavior of breast cancer cells Yonggang Lv, Xiaomei Zhang, Ying Zhang, Ya Wang O9-3 Preliminary study of endothelial cell tight junction protein in response to different mechanical stimuli Yazhou Wang, Desha Luo, Tieying Yin, Guixue Wang O9-4 PI3K-nos2b signaling is crucial for simulated microgravity-mediated angiogenesis in zebrafish CVP network Daoxi Lei, Guixue Wang O9-5 Ferric iron, lipopolysaccharide and lipoteichoic acids can induce anomalous fibrin amyloid formation: An assessment with novel Amytracker ^TM stains and thioflavin T Martin Page, Douglas Kell, Etheresia Pretorius 13.00–14.30 Symposia S30-S32 S30: FROM RHEOLOGY TO MICROCIRCULATION: NEW INSIGHTS Chairs: Gregorio Caimi and Antonio Colantuoni S30-1 Red blood cell rheology under different pathological conditions Patrizia Caprari, Carlotta Bozzi, Sara Massimi, Loretta Diana S30-2 Role of hemorheological alterations in skin ulcers Rosalia Lo Presti, Patrizia Caprari, Gregorio Caimi S30-3 Hemorheology in kidney disease Francesco Fontana S30-4 Rat pial microvascular changes during brain hypoperfusion and reperfusion injury: Role of antioxidant substances Martina Di Maro, Martina Chiurazzi, Dominga Lapi, Teresa Mastantuono, Laura Battiloro, Gilda Nasti, Antonio Colantuoni S30-5 Bridging the gap from basic microcirculation to the clinical world Romeo Martini, Antonio Colantuoni S31: CARDIOVASCULAR BIOMECHANICS FROM CELLS TO ORGANS Chairs: Noriyuki Kataoka and Ryoko Otomo S31-1 Biorheology of bile Minh Nguyen Ngoc, Hiromichi Obara, Kenji Shimokasa, Junfang Zhu S31-2 Electrical impedance spectroscopic technique for cancerous cell sensing by considering the extracellular fluid around cells Daisuke Kawashima, Songshi Li, Michiko Sugawara, Hiromichi Obara, Masahiro Takei S31-3 Matrix metalloprotease production of vascular endothelial cells under extremely high wall shear stress condition Naoya Sakamoto, Yuki Oyama, Yuta Horie, Masanori Nakamura, Naoyuki Kimura S31-4 Observation of microscopic elastic structure in arterial tissue by use of a scanning haptic microscope (SHM) Takeshi Moriwaki, Sadao Omata, Yasuhide Nakayama S31-5 Ultrafast imaging of cell elasticity with optical microelastography Guy Cloutier, Grasland-Mongrain, Ali Zorgani, Shoma Nakagawa, Simon Bernard, Lia Gomes Paim, Greg FitzHarris, Stefan Catheline S32: COMPUTATIONAL MODELS OF THROMBOSIS C Chairs: Keefe Manning and Shawn Shadden S32-1 The contact activation system in device-related thrombosis modeling Rodrigo Méndez Rojano, Simon Mendez, Franck Nicoud S32-2 Development of a device-induced computational thrombosis model Keefe Manning S32-3 Reduced-order computational modeling of thrombogenic potential in large arteries Kirk Hansen, Shawn Shadden POSTERS (P1-P36) P1 Effects of hypertrophy and strength weight training on resting levels and responses of hemorheological parameters to a single session of exercise Fatholah Havil, Afshar Jafaria, Sajad Ahmadizad, Saeed Nikoukheslat P2 Modulation of erythrocyte mechanical function by calcium-calmodulin-protein kinase C Ali Cenk AKSU, Yasemin AKSU, Dilan ATAR, Zeynep Busra Kısakurek, Elif Ugurel, Özlem Yalcin P3 Clinical relevance of hemodynamic viscosity measurement in vascular study Tilly Alexandre P4 Analysis of seismocardiographic signals by the discrete Chebyshev transform Mikhail Basarab, Natalya Konnova P5 Fetal growth retardation and oxygen delivery hemorheological predictors in hypertensive vs normotensive pregnant women Jean-Frédéric Brun, Emmanuelle Varlet-Marie, Pierre Boulot, Bénédicte Marion, Céline Roques, Eric Raynaud de Mauverger P6 Leg electrical resistance predicts venous blood viscosity and hematocrit Emmanuelle Varlet-Marie, Laurent Vachoud, Bénédicte Marion, Céline Roques, Marlène Richou, Eric Raynaud de Mauverger, Jean-Frédéric Brun P7 The transient hyperviscosity syndrome of labor and delivery shifts the hemorheological profile toward a lower ability to deliver oxygen to tissues Jean-Frédéric Brun, Pierre Boulot, Emmanuelle Varlet-Marie, Bénédicte Marion, Céline Roques, Eric Raynaud de Mauverger P8 Studies of the chemically induced changes of the mechanical properties of murine RBCs with the use of Atomic Force Microscopy (AFM) Katarzyna Bulat, Jakub Dybas, Aneta Blat, Mateusz Mardyla, Anna Rygula, Stefan Chłopicki, Małgorzata Baranska, Katarzyna M. Marzec P9 Investigation on energy characteristic of red blood cell deformability: A quantitative analysis of extending and retracting curves based on atomic force microscopy Dong Chen, Xiang Wang P10 Measurement of glycocalyx volume: An unreliable biomarker FitzRoy Curry, Charles Michel P12 Resonance Raman spectroscopy in detection and differentiation of various hemoglobin derivatives inside packed human red blood cells Jakub Dybas, Malgorzata Baranska, Stefan Chlopicki, Katarzyna M. Marzec P13 Effects of different rehabilitation models on the elongation index of erythrocytes, study of activity of chosen erythrocyte enzymes, and the level of glutathione in elderly women Katarzyna Filar-Mierzwa, Anna Marchewka, Zbigniew Dąbrowski, Paulina Aleksander-Szymanowicz P14 Effects of whole body vibration training on hemorheological blood indicators in young healthy women Halina Gattner, Justyna Adamiak, Magdalena Kępińska, Anna Piotrowska, Olga Czerwińska-Ledwig, Sylwia Mętel, Wanda Pilch P15 Evaluation of vascular effects of photodynamic therapy in skin microcirculation using different photosensitizers Tatyana Grishacheva, Dinara Faizullina, Nickolay Petrishchev, Irina Mikhailova P16 Analysis of flow and thrombus development within PDMS channels of varying geometry Tice Harkins, Jeremey Myslowski, Keefe Manning P17 Measurement of blood viscosity by measuring flows in microfluidic channel Hyeonji Hong, Eunseop Yeom P18 Repeated whole body cryotherapy treatments does not cause changes in hemorheological parameters in healthy people Magdalena Kępińska, Zbigniew Szyguła, Zbigniew Dąbrowski P20 Cell volume regulation via the calcium-activated potassium channel KCa3.1 contributes to red blood cell compliance under shear Jan Lennart Kuck, Michael J. Simmonds P21 Effects of rowing on rheological properties of blood Mateusz Mardyła, Aneta Teległów, Zbigniew Dąbrowski, Jakub Marchewka, Jacek Głodzik, Bartłomiej Ptaszek P22 Impaired deformability of erythrocytes in hypertensive rats and patients: Investigation by nickel mesh filtration technique Toru Maruyama, Keita Odashiro, Takehiko Fujino, Shiro Mawatari P23 Determinants of sublethal trauma to red blood cells: Effects of shear rate at standardized shear stresses Jacob Turner, Antony McNamee, Jarod Horobin, Lennart Kuck, Kieran Richardson, Michael Simmonds P24 Susceptibility to mechanical damage of density-fractionated red blood cells Antony McNamee, Kieran Richardson, Lennart Kuck, Kai Robertson, Michael Simmonds P25 Clinical evaluation of laser Doppler flowmetry for diagnosis of microcirculatory disorders Christof Mrowietz, R.P. Franke, G. Pindur, R. Sternitzky, F. Jung, U. Wolf P26 Erythrocytes aggregation index correlate with oxidative stress and hydrogen sulfide plasma concentration in diabetes mellitus Agata Pietrzycka, Katarzyna Krzanowska, Przemysław Miarka, Władysław Sułowicz, Marcin Krzanowski P27 Effects of carboxylated multiwall carbon nanotubes on erythrocytes stability and functionality Mateusz Przetocki, Józef Korecki, Grzegorz Gajos, Leszek Stobiński, Krzysztof Matlak, Kvetoslava Burda P28 Influence of different rhythms sound wave to serotonin concentration in rats hippocampus Yang Ren, Zhidan Deng, Xiang Wang P29 Physical properties of erythrocytes improve in hemochromatosis patients with repeated venesection therapy Kieran Richardson, Antony McNamee, Michael Simmonds P30 Experimental characterization of the embolus trapping efficiency of the U.S. FDA generic inferior vena cava filter Joshua Riley, Nicole Price, Brent Craven, Kenneth Aycock, Keefe Manning P31 Effects of pentoxifylline on hemodynamic and hemorheological parameters in SHRs during arterial hypertension development Alexander Shamanaev, Oleg Aliev, Anastasia Sidekhmenova, Anna Anischenko, Mark Plotnikov P32 Effect of cholesterol-rich diet on hematological and hemorheological parameters in rabbits Bence Tanczos, Viktoria Somogyi, Mariann Bombicz, Bela Juhasz, Norbert Nemeth, Adam Deak P33 Changes in biochemical properties of the blood in winter swimmers Aneta Teległów, Jakub Marchewka, Anna Marchewka, Zbigniew Dąbrowski, Bartłomiej Ptaszek, Mateusz Mardyła P34 The paraclinical evolution in diabetic hypertensive patients with increased abdominal circumference Cornel Cezar Tudorica, Ana Maria Vintila, Stefan Dragos Tudorica, Mirela Gherghe P35 Alterations of red blood cell deformability and mechanical stability by heat-treatment on animal blood samples Gabor Varga, Adam Attila Matrai, Balazs Szabo, Viktoria Somogyi, Barbara Barath, Bence Tanczos, Norbert Nemeth P36 Shear-dependency of the predicted ideal hematocrit Emmanuelle Varlet-Marie, Laurent Vachoud, Bénédicte Marion, Céline Roques, Marlène Richou, Eric Raynaud de Mauverger, Jean-Frédéric Brun