Novel 2-iminochromene dimers were prepared in excellent yields (93–99%) and with high to excellent enantioselectivities (89–97% ee) by a simple and efficient method. The precursor 2-[(3-cyano-2H-chromen-2-ylidene)amino]acetates and both racemic and enantioselective 2-iminochromene dimers were disclosed and characterised for the first time.
LiW., HuangJ., and WangJ., Org. Biomol. Chem., 2013, 11, 400.
14.
HauglandR. P., Handbook of fluorescent probes and research products, 9th edn, Molecular Probes, 2002.
15.
GreenG. R., EvansJ. M., and VongA. K., In Comprehensive heterocyclic chemistry II, eds KatritzkyA., ReesC. W., ScrivenE. F. V.Pyrans and their benzo derivatives: applications.Pergamon, Oxford, 1996, Vol. 5, Chap. 5.09, pp 469–500.
16.
BurkeT. R., LimB., MarquezV. E., LiZ. H., BolenJ. B., StefanovaI., and HorakI. D. J., J. Med. Chem., 1993, 36, 425.
17.
HuangC. K., WuF. Y., and AiY. X., Bioorg. Med. Chem. Lett., 1995, 5, 2423.
18.
DaiL., XuD., TangL., and ZhouZ.ChemCatChem (in press doi: 10.1002/cctc.201403048R1).
19.
VolmajerJ., ToplakR., LebanI., and Le MarechalA. M., Tetrahedron, 2005, 61, 7012.
20.
ShynkarenkoP. E., VlasovS. V., KovalenkoS. M., ShishkinaS. V., ShishkinO. V., and ChernykhV. P., J. Heterocycl. Chem., 2010, 47, 800.
