Efficient One-Pot Three-Component Reaction for the Synthesis of (5-Aryl-1,3,4-Oxadiazol-2-Yl)(Pyridin-2-Yl)Methanol Derivatives

Abstract

(N-Isocyanimino)triphenylphosphorane, 2-pyridinecarbaldehyde and four halogenated aromatic carboxylic acids undergo a 1 : 1 : 1addition reaction under mild conditions in a one-pot reaction to afford four novel (5-aryl-1,3,4-oxadiazol-2-yl)(pyridin-2-yl)methanol derivatives in good yields.